2024
DOI: 10.3390/foods13131973
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In Silico Screening of Bioactive Peptides in Stout Beer and Analysis of ACE Inhibitory Activity

Wenhui Tian,
Cui Zhang,
Qi Zheng
et al.

Abstract: Stout beer was selected as the research object to screen angiotensin-converting enzyme (ACE) inhibitory peptides. The peptide sequences of stout beer were identified using ultra-performance liquid chromatography-quadrupole-Orbitrap mass spectrometry with de novo, and 41 peptides were identified with high confidence. Peptide Ranker was used to score the biological activity and six peptides with a score ≥ 0.5 were screened to predict their potential ACE inhibitory (ACEI) activity. The toxicity, hydrophilicity, a… Show more

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