In situ antibiofilm effect of glass-ionomer cement containing dimethylaminododecyl methacrylate

A novel coping metal material CoCrCu alloy fabricated by selective laser melting with antimicrobial and antibiofilm properties

“…Among the bio-active functions proposed for dental materials, antibacterial activity seems the most promising [17,29]. The use of CoCr based alloys has become popular in recent years as a coping material for use in restorative dentistry [6,7].…”

“…Hence, a dental biomaterial that creates a sustained antimicrobial environment around the restoration and is able to discourage biofilm formation would be of considerable clinical benefit [17]. To this end, several antimicrobial agents have been incorporated within restorative materials and bonding systems [16].…”

“…Christian Apel et al developed composite materials containing the biomolecule carolacton, which could inhibit the biofilm growth of Streptococcus mutans UA159 and is therefore potentially able to prevent secondary caries formation[28]. Jin Feng et al recently developed a glass ionomer cement (GIC) containing dimethylaminododecyl methacrylate (DMADDM), which has antibiofilm effects as shown by bacterial morphological changes and decreased biofilm accumulation under oral conditions[17].Ideally, the antimicrobial activity of dental materials should be addressed as regards to their biofilm inhibitory effects.The excellent antibacterial effect of SLM CoCrCu is likely to be attributed to the copper ions releasing from its surface. Some studies concerning Cu-bearing biomaterials suggest that their antibacterial effects are due to the copper ions leaching from the material's surface.…”

Heat-Polymerized Resin Containing Dimethylaminododecyl Methacrylate Inhibits Candida albicans Biofilm

“…Several other non-released antibacterial materials were recently reported, such as methacryloxylethylcetyl dimethylammoniumchloride (DMAE-CB) containing adhesive, antibacterial glass ionomer cements, antibacterial nanocomposites, and bonding agents using a quaternary ammoniumdimethacrylate (QADM). Dimethylaminododecyl methacrylate (DMADDM), a new kind of QAMs, was also added to composite resin, bonding agent, and glass-ionomer cement as a non-releasing agent, which has witnessed an antibacterial effect [25,26,27,28]. However, only a few articles described the QAMs (MDPB) as additives in acrylic resin to study the antibacterial activity of the new materials [29,30] and no antifungal investigation of the QAM-modified acrylic resin has been reported.…”

Adsorption and desorption behaviors of cetylpyridinium chloride on hydroxyapatite nanoparticles with different morphologies

“…Direct restorative materials (such as composite resins and glass ionomer cements) with antibacterial properties have been developed [8][9][10][11][12] to avoid secondary caries resulting from plaque formation on restorative materials, which has been reported as the main cause of restoration failure 13) . Thus, the incorporation of antibacterial properties into nanoparticulate repair agents should be an effective method to restore the damaged enamel and prevent the formation of secondary caries; however, there have been few reports on the subject to date.…”