In situ decoration of TiO2 nanowire microspheres with silk fibroin for enhanced biocompatibility

Zhang, Cunfang; Zhang, Xinyan; Chen, Song; Zhang, Jialan; Li, Shuaishuai; Li, Xiaona; Ikoma, Toshiyuki; Chen, Weiyi

doi:10.1016/j.matlet.2022.132688

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…Meinel [ 58 ] verified that the inflammatory response in vivo caused by silk fibroin film was equal to or smaller than that observed on collagen film and far smaller than that of polylactic acid film. TiO 2 microspheres decorated with silk fibroin in situ showed enhanced biocompatibility compared with TiO 2 microspheres [ 59 ].…”

Section: Structure and Properties Of Silk Fibroinmentioning

confidence: 99%

Silk Fibroin Microneedles for Transdermal Drug Delivery: Where Do We Stand and How Far Can We Proceed?

Yan

Tan

et al. 2023

Pharmaceutics

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Microneedles are a patient-friendly technique for delivering drugs to the site of action in place of traditional oral and injectable administration. Silk fibroin represents an interesting polymeric biomaterial because of its mechanical properties, thermal stability, biocompatibility and possibility of control via genetic engineering. This review focuses on the critical research progress of silk fibroin microneedles since their inception, analyzes in detail the structure and properties of silk fibroin, the types of silk fibroin microneedles, drug delivery applications and clinical trials, and summarizes the future development trend in this field. It also proposes the future research direction of silk fibroin microneedles, including increasing drug loading doses and enriching drug loading types as well as exploring silk fibroin microneedles with stimulation-responsive drug release functions. The safety and effectiveness of silk fibroin microneedles should be further verified in clinical trials at different stages.

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Section: Structure and Properties Of Silk Fibroinmentioning

confidence: 99%

Silk Fibroin Microneedles for Transdermal Drug Delivery: Where Do We Stand and How Far Can We Proceed?

Yan

Tan

et al. 2023

Pharmaceutics

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Biocompatibility of biomaterials and test methods: a review

2023

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Biomaterials research has gained considerable momentum recently. The development of technology and the changing human lifestyles have also changed human health needs. The developed materials for use in different areas like in medical products and living bodies have necessitated adding biocompatibility to the mechanical, physical, and chemical properties of these materials. This article is a review of the concept and evaluation of biocompatibility. It explains how biomaterials change with the development of technology, human changing lifestyles, and needs, and how these materials are developed with the same technology. It contains what biocompatibility is, the factors that affect biocompatibility, what can happen in case of low biocompatibility, and the standards and work plans required for tests such as hemocompatibility, genotoxicity, toxicokinetic, and immunotoxicology for biocompatibility..

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In situ decoration of TiO2 nanowire microspheres with silk fibroin for enhanced biocompatibility

Cited by 2 publications

References 12 publications

Silk Fibroin Microneedles for Transdermal Drug Delivery: Where Do We Stand and How Far Can We Proceed?

Silk Fibroin Microneedles for Transdermal Drug Delivery: Where Do We Stand and How Far Can We Proceed?

Biocompatibility of biomaterials and test methods: a review

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