In situ electrogeneration of o-benzoquinone and high yield reaction with benzenethiols in a microflow system

Abstract

We have successfully demonstrated that a microflow reactor is extremely useful in controlling reactions involving an unstable o-benzoquinone. The key features of the method are an effective o-benzoquinone generation and its rapid use for the following reaction without decomposition in a microflow system.

Moderne Aspekte der Elektrochemie zur Synthese hochwertiger organischer Produkte

“…[135] Der Prozess wurde später optimiert [136] und auf weitere elektrochemische Umsetzungen ausgeweitet, wie die Bildung von Ketalen aus Chinonen, Fluorierung,C e IV -Generierung und die Synthese von Estern und Amiden aus Aldehyden. [138] Hierbei ist anzumerken, dass die erhaltenen Ausbeuten fürd en kontinuierlichen Prozess deutlich hçher waren als fürd en nicht kontinuierlichen Prozess im Kolben. [138] Hierbei ist anzumerken, dass die erhaltenen Ausbeuten fürd en kontinuierlichen Prozess deutlich hçher waren als fürd en nicht kontinuierlichen Prozess im Kolben.…”

Carbon Electrodes in Electrochemical Technology

“…The ability to achieve this as well as minimizing the use of electrolyte makes the technique of greater interest to synthetic organic chemists and also aids the isolation of pure product. Several designs have been reported [65][66][67][68][69] and some are making use of carbon-filled polymer composites as ideal electrode materials; they combine chemical inertness and flatness with acceptable conductivity and they are less brittle than vitreous carbon or graphite, making them easier to fabricate and handle. For example, one design [69] uses a flat anode plate made from carbon-filled polyvinylidene fluoride (PVDF).…”

Electrochemical Reactions in Microreactors

“…The anodic oxidation of catechols in an electrochemical flow microreactor gave o-benzoquinones, which were reacted with benzenethiols to obtain the coupled products [29]. [24] Reaction Anodic methoxylation of p-methoxytoluene.…”