In-situ fabrication of zeolite imidazole framework@hydroxyapatite composite for dispersive solid-phase extraction of benzodiazepines and their determination with high-performance liquid chromatography-VWD detection

Benzodiazepines in complex biological matrices: Recent updates on pretreatment and detection methods

“…Li et al. [ 119 ] synthesized a chemically stable and reusable composite of zeolite imidazole framework@hydroxyapatite (ZIF-8@HAP) as the DSPE adsorbent for extracting three BDZs from urine. The surface area of the prepared composite was nearly 44 folds compared with that of single HAP, contributing to a high recovery of 88.7%–102.0%.…”

“…LC is a widely used analytical technique for separations based on the selectivity of components in the mixture for the stationary and mobile phases. The application of the LC method for BDZs is shown in Table S5 [ [21] , [22] , [23] , [24] , [27] , [28] , [29] , [30] , 32 , 34 , [39] , [40] , [41] , [42] , [44] , [45] , [46] , [47] , 49 , 51 , [58] , [59] , [60] , [61] , 63 , 65 , [69] , [70] , [71] , [73] , [74] , [75] , [76] , [77] , [78] , 81 , [87] , [88] , [89] , [90] , [91] , [92] , [93] , [95] , [96] , [97] , [98] , [99] , [100] , [101] , [102] , [104] , [105] , [106] , [107] , [109] , [110] , [111] , [112] , 115 , [119] , [120] , [121] , …”