In Situ Generated Dye@MOF/COF Heterostructure for Fluorescence Detection of Chloroquine Phosphate and Folic Acid via Different Luminescent Channels

Abstract

Metal-organic framework (MOF) and covalentorganic framework (COF) hybrid materials can combine the unique properties of MOF and COF components, and their applications in fluorescence sensing have attracted more and more attention. Herein, ZIF-90 is grown on 3D-COF by a simple in situ growing method in which the 7-amino-4-methylcoumarin (AMC) is encapsulated in ZIF-90 to construct a fluorescent sensor. Chloroquine phosphate (CQP) can coordinate with Zn 2+ to decompose the ZIF-90 and release AMC. At 365 nm excitation, the ratiometric fluorescence signal AMC/3D-COF (I 430 /I 598 ) increases linearly with CQP in a linear range of 4 × 10 −5 to 4 × 10 −4 M in urine. Under 340 nm excitation, quantitative analysis of CQP in the serum (3 × 10 −6 to 4 × 10 −5 M) is based on the fluorescence intensity of Zn-CQP/3D-COF (I 384 /I 598 ). In addition, AMC@ZIF-90/3D-COF (1) exhibits high anti-interference and selectivity in sensing of FA with a "turn off" mode, with a correlation range of 1 × 10 −5 to 1 × 10 −3 M. The fluorescence color changes triggered by CQP under different excitation conditions, and the different fluorescence responses caused by CQP make it a highly secure anticounterfeiting platform. The synthesized dye@MOF/COF hybrids not only provide a new way to integrate multiple emission to design fluorescent probes for differentiation detection but also offer ideas for the design of anticounterfeiting platforms.

Multicolor Fluorescent Inks Based on Lanthanide Hybrid Organogels for Anticounterfeiting and Logic Circuit Design

“…Over the past few decades, a variety of technologies, such as hologram, watermarking, security code, , and fluorescent pattern, , have been developed for anticounterfeiting application. Among the existing anticounterfeiting technology, the fluorescent materials are widely used because of their color luminescence, good visibility, and simple design. − With the development of anticounterfeiting technology, the main manifestation is the continuous preparation of luminescent materials with highly designable properties, which include organic dyes, , nanoparticles and carbon dots, − and lanthanide luminescent materials, − enabling the fluorescent color diversity of anticounterfeit marks. Among them, lanthanide photoluminescent materials have unique luminescent properties such as high color purity, unique narrow emission, and long luminescence lifetime .…”

Efficient Multi-stimulus-Responsive Luminescent Eu(III)-Modified HOFs Materials: Detecting Thiram and Caffeic Acid and Constructing a Flexible Substrate Anti-counterfeiting Platform

“…Fluorescence sensors have gained attention from researchers due to their various advantages, such as low cost, ease of use, portability, and real-time monitoring. , Hydrogen-bonded organic frameworks (HOFs) are assembled based on hydrogen bonding, van der Waals forces, and π–π stacking, and benefiting from an abundance of hydrogen-bonded acceptor and donor sites, HOFs can be conjugated to lanthanide (Ln 3+ ) ions through postsynthetic modification (PSM) to generate Ln@HOFs. , Owing to the combination of the excellent optical properties of Ln 3+ ions with the inherent physicochemical properties of HOFs, Ln 3+ -functionalized HOFs (Ln@HOFs) differ from conventional Ln 3+ -hybridized materials . Ln@HOFs, as a novel type of luminescent material, has great potential in the field of fluorescence sensing and anti-counterfeiting, with the following merits.…”