In-Situ Preparation of Poly(butylene succinate-co-butylene fumarate)/Hydroxyapatite Nanocomposite

Abstract

A three-step in situ polymerzition method was used to synthesize short-segmented block copolymers of poly­(butylene succinate-co-butylene fumarate)/nano hydroxyapatite nanocomposites. The nanocomposites were characterized by 1H NMR and Fourier transform infrared spectroscopy. The bond formed between nanohydroxyapatite and polymer led to a good particle dispersion which was studied using scanning electron microscopy (SEM). The thermal and crystallization properties of nanocomposites were calculated via differential scanning calorimetry and X-ray diffraction, indicating the formation of the complete crystals with two different sizes. Producing nanofiber from nanocomposites was done using the electrospinning method. According to SEM results, nanofibers were continuous and bead-free and those produced from nanocomposites had larger fiber diameter compared to the neat copolyester. In contrast to tensile strength, elastic modulus, hydrolytic degradability, and hydrophilicity of the resulted nanofiber which were increased with the nanoparticle, the elongation at break was slightly decreased.

LAPONITE® nanorods regulating degradability, acidic-alkaline microenvironment, apatite mineralization and MC3T3-E1 cells responses to poly(butylene succinate) based bio-nanocomposite scaffolds

“…[10][11][12][13] The great research efforts for designing the ideal bio-nanocomposite scaffolds for repair and regeneration of damaged/diseased tissues have revealed the promise of polymer based bio-nanocomposite scaffolds, which exhibited superior biological properties for bone tissue engineering because allowed tailoring the desired bioactivity, degradation and resorption kinetics of the scaffolds. [14][15][16] Moreover, nanosized bioactive llers incorporated in the polymeric scaffolds offer the required osteoconductivity and biocompatibility features that are able to improve the cell adhesion, proliferation and differentiation, as well as, new bone tissue ingrowth into the scaffolds, and ultimately repair bone defects. 12,17 Furthermore, the bio-nanocomposite scaffolds containing polymers and bioactive nanoparticles hold nanofeatured structures with improved properties, such as high surface area, fast degradation rate, enhanced hydrophilicity, bioactivity and mechanical properties that are a must for the appropriate cellular adhesion, proliferation and differentiation, and bone defects repair.…”

Flame retardancy and thermal properties of poly(butylene succinate)/ nano‐boehmite composites prepared via in situ polymerization

“…[21] PBS, as a promising biodegradable polyester, and its nanocomposites have been intensively studied in our group. [22][23][24] Flame retardancy of PBS was improved by adding ammonium polyphosphate (APP), melamine (MA), pentaerythritol (PER), and halloysite nanotubes (HNTs) via melt blending. Then, flame retardancy, thermal, and mechanical properties of IFR-PBS composites were investigated.…”