2018
DOI: 10.1002/cptc.201800180
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In Situ Synthesis of Dicarboxylic Acid Functionalized Upconversion Nanoparticles for Bioimaging Applications

Abstract: We report a one‐step strategy to synthesize, in situ, highly water‐dispersible NaYF4 : Yb/Er upconversion nanoparticles (UCNPs) by employing dicarboxylic acids. The dicarboxylic acids serve as a type of dual‐purpose surface ligand for both controlling the growth and enabling the water dispersibility of the NaYF4 : Yb/Er UCNPs. It is found that the carbon chain length of the dicarboxylic acids has a marked effect on the size and morphology of the UCNPs. Among the dicarboxylic acids studied, adipic acid shows a … Show more

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Cited by 8 publications
(3 citation statements)
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“…There are many modified methods of molecular bioimaging systems such as MRI, optical imaging, ultrasound imaging, positron emission tomography, and many others. These have been adapted for in vitro and in vivo biological treatment (Chen et al, 2018;Ferenz and Zhang, 2018;Pratiwi et al, 2019;Wang M. et al, 2019). In the study of metallic nanoparticles, an upgraded bioimaging technology such as MRI and optical imaging has been introduced.…”
Section: Bioimaging Applicationmentioning
confidence: 99%
“…There are many modified methods of molecular bioimaging systems such as MRI, optical imaging, ultrasound imaging, positron emission tomography, and many others. These have been adapted for in vitro and in vivo biological treatment (Chen et al, 2018;Ferenz and Zhang, 2018;Pratiwi et al, 2019;Wang M. et al, 2019). In the study of metallic nanoparticles, an upgraded bioimaging technology such as MRI and optical imaging has been introduced.…”
Section: Bioimaging Applicationmentioning
confidence: 99%
“…As-synthesized silver nanoparticles either capped with hydrophilic ligands or carboxylic acids have also been reported to detect Hg+ at ppm levels [ 33 , 41 ]. The nanoparticles with different carboxylic acids on their surface have been characterized previously, where the NPs capped with adipic acid were comparatively more uniform and mono-disperse, hence suitable for biological applications [ 42 ]. Our research goal was to prepare AgNPs capped with adipic acid (AgNPs@AA).…”
Section: Introductionmentioning
confidence: 99%
“…Spectrally shifting, upconverting nanoparticles (UCNPs), based on NaYF 4 that show photoluminescence (PL) in the ultraviolet (UV), visible, and near-infrared (NIR) regions, have drawn considerable attention due to their potential for applications in photocatalysis, [1] bioimaging and sensing, [2][3][4][5][6] non-invasive luminescence thermometry, [7,8] drug delivery, [9][10][11] extending the absorption range of solar energy devices, [12][13][14][15] and use in other optical devices. [16][17][18] During upconversion with Yb 3+ and Er 3+ doped NaYF 4 UCNPs, the sensitizer ions (Yb 3+ ) absorb NIR photons and transfer the energy of two or more photons to an activator ion (Er 3+ ).…”
Section: Introductionmentioning
confidence: 99%