In-the-bag intraocular lens dislocation

Late in-the-bag intraocular lens dislocation requiring explantation: risk factors and outcomes

“…In these studies, some features are detected as predisposing factors. Zonular weakness has been associated to PEX, [4][5][6][7]9 uveitis, 6 trauma, 6,10 high myopia, 11 vitreoretinal surgery, 12 retinitis pigmentosa, 13 and connective tissue disorders, such as Marfan's syndrome, homocystinuria, hyperlysinemia, Ehler-Danlos, scleroderma, and Weil-Marchesani. 14 In our study, the most prevalent risk factor was high myopia in 12 cases (19.7%).…”

“…This surprising result has also been found by other authors. 6,23,25 This is difficult to explain because more women than men undergo cataract surgery 26 and have PEX. 27 Thus, some investigators suggest that there may be a gender-related difference that results in weaker zonulae in men with PEX.…”

“…On the contrary, in the other case series published to date, PEX was the most important risk factor. 1,6,8,23 Lorente et al, 7 in a recent study also performed in Spain, showed that PEX was found in 66.6% of the cases (30 eyes), whereas high myopia was only detected in 1 case (2.22%). This emphasizes that PEX incidence depends highly on the geographical location, even within a small country such as Spain.…”

“…The risks factors for this condition include pseudoexfoliation (PEX), connective tissue disorders, uveitis, retinitis pigmentosa, high myopia, and patients who underwent vitreoretinal surgery. [4][5][6] Bag dislocation in these situations usually occurs a long time after cataract surgery, with a mean interval of 6.9-8.5 years. [5][6][7][8] Surgical management of this condition is usually complex and may be associated to new complications.…”

“…[4][5][6] Bag dislocation in these situations usually occurs a long time after cataract surgery, with a mean interval of 6.9-8.5 years. [5][6][7][8] Surgical management of this condition is usually complex and may be associated to new complications. Explantation of the whole capsular bag with implantation of a sulcus sutured IOL or an anterior chamber IOL is often required.…”