In the shadow of the wrinkle: experimental models

Humbert, P.; Viennet, Céline; Legagneux, Kévin; Grandmottet, François; Robin, Sophie; Muret, Patrice

doi:10.1111/j.1473-2165.2011.00601.x

Cited by 12 publications

(6 citation statements)

References 34 publications

(58 reference statements)

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“…Knowledge on the biological process of skin chronological and photo‐aging is still increasing thanks to cross‐sectional results generated from human, animal and in vitro studies. However, as mouse skin is somehow different from human skin, the innovative model of wrinkling human skin xenograft on severe combined immunodeficiency mice seems to be really promising (Humbert et al ., ). Nevertheless, the cause and occurrence mechanism of the coarser lines on aging individual's skin are not yet fully understood (Humbert et al ., ).…”

Section: Anti‐aging Effectmentioning

confidence: 97%

Skin Health Promotion Effects of Natural Beta‐Glucan Derived from Cereals and Microorganisms: A Review

Bian

2013

Phytotherapy Research

161

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β-Glucans are natural cell wall polysaccharides found in yeast, fungi (including mushrooms), some bacteria, seaweeds and cereals. Natural β-glucans possess many health promotion effects on human health, such as anti-tumor, anti-diabetes, anti-infection, lowering blood cholesterol and immune-modulating properties. These effects have been reviewed previously. However, skin health promotion of β-glucan derived from cereals and microorganisms has received little attention. This review focuses on antioxidant activity, anti-wrinkle activity, anti-ultraviolet light, wound healing, and moisturizing effect and skin permeation absorption of β-glucan. Furthermore, applications of β-glucan in cosmetics are also discussed.

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Section: Anti‐aging Effectmentioning

confidence: 97%

Skin Health Promotion Effects of Natural Beta‐Glucan Derived from Cereals and Microorganisms: A Review

Bian

2013

Phytotherapy Research

161

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“…Dermal torqueometry and in vivo ultrasound imaging show there is rigidification of the stratum corneum with loss of echogenicity and weakening in the upper dermis that leads to wrinkles . Other causes of wrinkle formation include loss of retinaculum cutis and thinning of dermis , thickening of the stratum corneum and thinning of the stratum spongiosum , thinning of the epidermis and loss of collagens IV and VII at dermoepidermal junction at the base of the wrinkle . This suggests that changes in any one of the tissue properties of the fibrous lamellar components of the skin can result in the surface buckling.…”

Section: Age Differencesmentioning

confidence: 99%

The dynamic anatomy and patterning of skin

Wong

Geyer

Weninger

et al. 2015

Experimental Dermatology

307

201

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The skin is often viewed as a static barrier that protects the body from the outside world. Emphasis on studying the skin's architecture and biomechanics in the context of restoring skin movement and function is often ignored. It is fundamentally important that if skin is to be modelled or developed, we do not only focus on the biology of skin but also aim to understand its mechanical properties and structure in living dynamic tissue. In this review, we describe the architecture of skin and patterning seen in skin as viewed from a surgical perspective and highlight aspects of the microanatomy that have never fully been realized and provide evidence or concepts that support the importance of studying living skin's dynamic behaviour. We highlight how the structure of the skin has evolved to allow the body dynamic form and function, and how injury, disease or ageing results in a dramatic changes to the microarchitecture and changes physical characteristics of skin. Therefore, appreciating the dynamic microanatomy of skin from the deep fascia through to the skin surface is vitally important from a dermatological and surgical perspective. This focus provides an alternative perspective and approach to addressing skin pathologies and skin ageing.

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“…It is noteworthy that cosmetic dermatology is fighting against wrinkles as the most disliked signs of skin aging and preventing them is the major topic for contemporary cosmetic laboratories 20 . Research studies on the still unknown biophysical process of the progressively altered skin have a strong concern about avoiding dangerous products 21 …”

Section: Introductionmentioning

confidence: 99%

The Byzantine Empress Zoe Porphyrogenita and the quest for eternal youth

Πάνας

Poulakou‐Rebelakou²,

Kalfakis

et al. 2012

J of Cosmetic Dermatology

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The diachronically continuous struggle for eternal youth as represented by the Byzantine Empress Zoe Porphyrogenita (978-1050). The presentation of a beautiful empress, trying to keep her youth appearance until a prolonged age, applying on herself cosmetic essences and fragrances made in her personal laboratory into the imperial palace. The review of the relevant literature and the historical evidence derived from the historians and chroniclers of her era, as well as the surviving images of Zoe. The eye-witness chroniclers of the era describe her as blonde, with bright white skin, lack of wrinkles, and a very young girl appearance, preserving her beauty even into her 60s. All the historical sources agree that her main occupation was the manufacture of cosmetic essences, and for this purpose, she had installed a laboratory (myrepseion) in her private quarters, where she prepared various drugs and perfumes, spending much of her time for these activities. It is noteworthy that her first two husbands died under circumstances that aroused suspicions of Zoe's involvement in their deaths, as she had parallel love affairs. The best known image of Zoe is the mosaic panel in Saint Sophia, the cathedral Church of Constantinople and her representation has been long discussed, as she was 64 years old at the time of the scene apparently depicted in the panel, and maybe she took the opportunity of adding a more pleasing portrait of herself. The preservation of beauty is a timeless quest and cosmetic dermatology has its origins in antiquity and medieval times.

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In the shadow of the wrinkle: experimental models

Cited by 12 publications

References 34 publications

Skin Health Promotion Effects of Natural Beta‐Glucan Derived from Cereals and Microorganisms: A Review

Skin Health Promotion Effects of Natural Beta‐Glucan Derived from Cereals and Microorganisms: A Review

The dynamic anatomy and patterning of skin

The Byzantine Empress Zoe Porphyrogenita and the quest for eternal youth

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