In-vial dried urine spot collection and processing for quantitative analyses

Dvorak, M.W.; Maršala, Richard; Kubáň, Pavel

doi:10.1016/j.aca.2023.341071

Cited by 4 publications

(1 citation statement)

References 44 publications

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“…This could help future epidemiological and medical research since web-based data collection can have advantages in collecting data from minority populations and from hard-to-reach populations [93][94][95][96]. This is not limited to self-report surveys such as ours since many aspects of data collection, including, for example, some biological assays [97][98][99][100], neurobehavioral and cognitive assessments [101][102][103], stress tests [104,105], and parent-child observations [106], have been successfully adapted to be conducted remotely. Finally, our data on social media advertisement costs and success will also be documented and could help inform recruitment budgets for future web-based studies on pregnant populations.…”

Section: Discussionmentioning

confidence: 99%

Phenotypic Environmental Sensitivity and Mental Health During Pregnancy and Post Partum: Protocol for the Experiences of Pregnancy Longitudinal Cohort Study

Rioux,

Fulp,

Haley

et al. 2023

JMIR Res Protoc

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Background Mental health problems during pregnancy and post partum are common and associated with negative short- and long-term impacts on pregnant individuals, obstetric outcomes, and child socioemotional development. Socio-environmental factors are important predictors of perinatal mental health, but the effects of the environment on mental health are heterogeneous. The differential susceptibility theory and the environmental sensitivity framework suggest that individuals differ in their degree of sensitivity to positive and negative environments, which can be captured by individual phenotypes such as temperament and personality. While there is strong evidence for these models in childhood, few studies examined them in adults, and they were not examined in pregnancy. Objective The primary objective of the Experiences of Pregnancy study is to explore whether childhood and current environments are associated with mental health and well-being in pregnancy and whether these effects depend on individual sensitivity phenotypes (personality). This study also aims to gather important psychosocial and health data for potential secondary data analyses and integrative data analyses. Methods We will conduct a longitudinal cohort study. The study was not registered elsewhere, other than this protocol. Participants will be recruited through social media advertisements linking to the study website, followed by an eligibility call on Zoom (Zoom Video Communications). Participants must be aged 18 years or older, currently residing in the United States as citizens or permanent residents, and currently planning to continue the pregnancy. A minimum of 512 participants will be recruited based on power analyses for the main objectives. Since the data will also be a resource for secondary analyses, up to 1000 participants will be recruited based on the available budget. Participants will be in their first trimester of pregnancy, and they will be followed at each trimester and once post partum. Data will be obtained through self-reported questionnaires assessing demographic factors; pregnancy-related factors; delivery, labor, and birth outcomes; early infant feeding; individual personality factors; childhood and current environments; mental health and well-being; attachment; and infant temperament. A series of measures were taken to safeguard the study from web robots and fraudulent participants, as well as to reduce legal and social risks for participants following Dobbs v. Jackson. Results The study received ethics approval in April 2023 from the University of Oklahoma-Norman Campus Institutional Review Board. Recruitment occurred from May to August 2023, with 3 follow-ups occurring over 10 months. Conclusions The Experiences of Pregnancy study will extend theories of environmental sensitivity, mainly applied in children to the perinatal period. This will help better understand individual sensitivity factors associated with risk, resilience, plasticity, and receptivity to negative and positive environmental influences during pregnancy for pregnant individuals. International Registered Report Identifier (IRRID) PRR1-10.2196/49243

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Section: Discussionmentioning

confidence: 99%

Phenotypic Environmental Sensitivity and Mental Health During Pregnancy and Post Partum: Protocol for the Experiences of Pregnancy Longitudinal Cohort Study

Rioux,

Fulp,

Haley

et al. 2023

JMIR Res Protoc

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Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

Hauser,

Kubáň

2024

Electrophoresis

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The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of the detector and complete electrophoresis instrumentation.

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Phenotypic Environmental Sensitivity and Mental Health During Pregnancy and Post Partum: Protocol for the Experiences of Pregnancy Longitudinal Cohort Study (Preprint)

Rioux,

Fulp,

Haley

et al. 2023

Preprint

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BACKGROUND Mental health problems during pregnancy and postpartum are common and associated with negative short- and long-term impacts on pregnant individuals, obstetric outcomes, and child socioemotional development. Socio-environmental factors are important predictors of perinatal mental health, but effects of the environment on mental health are heterogeneous. The differential susceptibility theory and the environmental sensitivity framework suggest that individuals differ in their degree of sensitivity to positive and negative environment. While there is strong evidence for these models in childhood, few studies examined them in adults, and they were not examined in pregnancy. OBJECTIVE The primary objective of the Experiences of Pregnancy study is to explore whether childhood and current environments are associated with mental health and well-being in pregnancy, and whether these effects depend on individual sensitivity phenotypes (personality). The present study also aimed to gather important psychosocial and health data for potential secondary data analyses and integrative data analyses. METHODS 512 to 1000 participants will be recruited via social media ads linking to the study website, followed by an eligibility call on Zoom. Participants must be 18+ years of age, currently residing in the United States, and currently planning to keep the pregnancy. Participants will be in their first trimester of pregnancy and will be followed at each trimester and once postpartum. Data will be obtained through self-reported questionnaires assessing demographic factors, pregnancy-related factors, delivery, labor, and birth outcomes, early infant feeding, individual personality factors, childhood and current environments, mental health and well-being, attachment, and infant temperament. A series of measures were taken to safeguard the study from web robots and fraudulent participants, as well as to reduce legal and social risks for participants following Dobbs v. Jackson. RESULTS The study received ethics approval in April 2023. Recruitment will occur over Spring-Summer 2023 with 3 follow-ups over 10 months. CONCLUSIONS The Experiences of Pregnancy study will allow extending theories of environmental sensitivity mainly applied in children to the perinatal period. This will help better understand individual sensitivity factors associated with risk, resilience, plasticity, and receptivity to negative and positive environmental influences during pregnancy. In turn, this can help determine the best individualized interventions and treatments as well as inform targeted prevention and psychoeducation initiatives.

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In-vial dried urine spot collection and processing for quantitative analyses

Cited by 4 publications

References 44 publications

Phenotypic Environmental Sensitivity and Mental Health During Pregnancy and Post Partum: Protocol for the Experiences of Pregnancy Longitudinal Cohort Study

Phenotypic Environmental Sensitivity and Mental Health During Pregnancy and Post Partum: Protocol for the Experiences of Pregnancy Longitudinal Cohort Study

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

Phenotypic Environmental Sensitivity and Mental Health During Pregnancy and Post Partum: Protocol for the Experiences of Pregnancy Longitudinal Cohort Study (Preprint)

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