In Vitro Action of Meconium on Bronochomotor Tonus of Newborns with Meconium Aspiration Syndrome

Haliti, Arsim; Mustafa, Lirim; Bexheti, Sadi; Islami, Drita; Bozalija, Adnan; Shabani, Ragip; Islami, Hilmi

doi:10.3889/oamjms.2018.244

Cited by 4 publications

(2 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Consequently, it leads to hypercapnia, hypoxemia, vasoconstriction, increased peripheral vascular resistance, and difficulty obtaining intravenous access. 60, 61 Additionally, MAS may also lead to fluid extravasation during fluid administration.…”

Section: Extravasation Of Fluids Caused By Aspiration Pneumonia Due T...mentioning

confidence: 99%

Factors Influencing Extravasation of Newborn Intravenous Infusions: A Review

Huang,

Liao

et al. 2023

Explor Res Hypothesis Med

View full text Add to dashboard Cite

Newborns, with their low immune system, lack of self-care ability, and inability to express discomfort through language, face challenges during the treatment of diseases, especially during intravenous infusion treatments where extravasation can occur. The inability of nurses to immediately detect extravasation often leads to severe consequences, including disability and even death. This increases the pain and treatment costs for children and places a heavy burden on healthcare professionals, hospitals, and society. Neonatal infusion extravasation is widespread during intravenous infusion and is influenced by various factors. Therefore, this article aims to review the research progress on relevant influencing factors that cause neonatal infusion extravasation.

show abstract

Section: Extravasation Of Fluids Caused By Aspiration Pneumonia Due T...mentioning

confidence: 99%

Factors Influencing Extravasation of Newborn Intravenous Infusions: A Review

Huang,

Liao

et al. 2023

Explor Res Hypothesis Med

View full text Add to dashboard Cite

show abstract

“…К важным маркерам неблагоприятного течения интранатального периода относятся удлинение безводного периода (более 18 ч), характер околоплодных вод, обвитие пуповиной, стимуляция окситоцином [18]. Срав нительный анализ групп показал следующее (рис.…”

Section: таблица 2 возраст матерей в исследуемых группахunclassified

Risk factors for birth asphyxia

et al. 2022

View full text Add to dashboard Cite

Introduction. Intrauterine hypoxia and asphyxia during childbirth are the leading causes of infant mortality in the structure of certain conditions arising in the perinatal period.Purpose. To study the involvement of negative events for the fetus in the ante- and intranatal periods in the occurrence of perinatal asphyxia in newborns and identify the main modifiable risk factors that will allow formulating preventive strategies in the development of child hypoxia.Materials and methods. A retrospective assessment of the course of the ante- and intranatal period was carried out according to 50 case histories. Nominal data are presented with indication of absolute and relative values. Sets of quantitative indicators are described by the values of the median (Me) and the lower and upper quartiles (Q1–Q3). The χ2 test was used to compare unrelated samples. Differences were considered statistically significant at p < 0.05. Statistical data processing was carried out using the Microsoft Office 2021 software package.Results: In the group of children with moderate and severe asphyxia at birth, the median gestational age was 36 and 33 weeks. The main ante- and intranatal risk factors for asphyxia of newborns were established in the following percentage: fetoplacental insufficiency – 32%; premature rupture of membranes and medical abortions in history, 30% each; first pregnancy, anemia, obesity, hypertension, smoking, maternal age > 35 years, 18% each; isthmic-cervical insufficiency – 16%; history of antenatal death, threatened miscarriage, vaginitis, 14% each; acute respiratory infections during pregnancy, assisted reproductive technologies (IVF), uterine fibroids – 12% each; oligohydramnios – 8%; polyhydramnios – 6%.Conclusion. The structure of factors that can contribute to the development of asphyxia in newborns is diverse. Understanding the involvement of modifiable risk factors determines the need to build a strategy and tactics to reduce their impact on the development of the pathology under consideration.

show abstract

Surfactant lavage for neonatal meconium aspiration syndrome—An updated meta-analysis

Hui

Pan

Zou

et al. 2020

Journal of the Chinese Medical Association

View full text Add to dashboard Cite

Background: Surfactant lavage seems to have a good application prospect both in experimental models and patients with meconium aspiration syndrome (MAS). Data regarding the effect of surfactant lavage on pulmonary complications of MAS are conflicting. In view of these uncertainties, an updated meta-analysis including the latest literatures is performed. Methods: A search was conducted by two investigators involved in this research in PubMed, Embase, and Cochrane databases for studies in English and other languages, in Wanfang, VIP, and Cnki databases for Chinese studies (all last launched on December 18, 2018). Ultimately, we identified 11 original studies, including the surfactant lavage group (n = 189) and the control group (n = 204). Odds ratio and weighted mean difference were calculated using a random effects or fixed effects model, depending on the data type and heterogeneity of the included studies. Results: The comparison of effectiveness on MAS: (1) With respect to oxygen index at 48 hours stage and 72 hours stage, data showed significant difference between surfactant lavage/control groups (we/ighted mean difference [WMD] = −3.37, 95% confidence interval [CI], −5.68 ~ −1.06; p = 0.004 and 95% CI, −5.03 ~ −2.37; p < 0.00001). (2) With respect to days on mechanical ventilation, the analysis showed that there was significant difference between surfactant lavage group and control group (WMD = −1.12, 95% CI, −1.40 ~ −0.84; p < 0.00001). (3) Regarding the need for extracorporeal membrane oxygenation, days of oxygen therapy, and hospital stay, no significant differences were found. The comparison of possible complications of MAS: (1) Regarding pneumothorax, the analysis showed there was significant difference between surfactant lavage and control groups (odds ratio [OR] = 0.46, 95% CI, 0.24 ~ 0.85; p = 0.01). (2) With respect to mortality, persist pulmonary hypertension and pulmonary hemorrhage, the results showed no difference between the two groups. Conclusion: With respect to oxygen index and days on mechanical ventilation, surfactant lavage is significantly effective compared with control group, though didn’t eventually shorten days of oxygen therapy and hospital stay. In addition, our meta-analysis showed that surfactant lavage does not increase the risk of complications.

show abstract

In Vitro Action of Meconium on Bronochomotor Tonus of Newborns with Meconium Aspiration Syndrome

Cited by 4 publications

References 17 publications

Factors Influencing Extravasation of Newborn Intravenous Infusions: A Review

Factors Influencing Extravasation of Newborn Intravenous Infusions: A Review

Risk factors for birth asphyxia

Surfactant lavage for neonatal meconium aspiration syndrome—An updated meta-analysis

Contact Info

Product

Resources

About