In vitro and in vivo anthelmintic effects of Sterospermum kunthianum (Cham-Holl) leaf extract against Ascaridia galli in experimentally infected broiler chickens

Kyari, Stephen; Ajanusi, O.J.; Сулейман, М. М.; Orakpoghenor, Ochuko; Ogwiji, Matthew

doi:10.1007/s12639-021-01426-6

Cited by 5 publications

(2 citation statements)

References 14 publications

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“…Plant extracts are secondary plant metabolites that typically belong to classes of glucosinolates, isoprene derivatives, and flavonoids [ 203 ]. These compounds exhibit antimicrobial [ 204 ], antioxidant [ 205 ], anti-inflammatory [ 206 ], immune modulation [ 207 ], and anti-parasitic properties [ 205 , 208 ]. Supplementation of plant extracts in chicken diets stimulates the endocrine system [ 209 ], improves small intestinal digestion, and maintains gut microbial homeostasis [ 210 ].…”

Section: Control Of Necrotic Enteritis In the Post-antibiotic Eramentioning

confidence: 99%

Necrotic Enteritis in Broiler Chickens: A Review on the Pathogen, Pathogenesis, and Prevention

et al. 2022

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Clostridium perfringens type A and C are the primary etiological agents associated with necrotic enteritis (NE) in poultry. The predisposing factors implicated in the incidence of NE changes in the physical properties of the gut, the immunological status of birds, and the disruption of the gut microbial homeostasis, causing an over-proliferation of C. perfringens. The principal virulence factors contributing to the pathogenesis of NE are the α-toxin, β-toxin, and NetB toxin. The immune response to NE in poultry is mediated by the Th1 pathway or cytotoxic T-lymphocytes. C. perfringens type A and C are also pathogenic in humans, and hence are of public health significance. C. perfringens intoxications are the third most common bacterial foodborne disease after Salmonella and Campylobacter. The restrictions on the use of antibiotics led to an increased incidence of NE in poultry. Hence, it is essential to develop alternative strategies to keep the prevalence of NE under check. The control strategies rely principally on the positive modulation of host immune response, nutritional manipulation, and pathogen reduction. Current knowledge on the etiology, pathogenesis, predisposing factors, immune response, effect on the gut microbial homeostasis, and preventative strategies of NE in this post-antibiotic era is addressed in this review.

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Section: Control Of Necrotic Enteritis In the Post-antibiotic Eramentioning

confidence: 99%

Necrotic Enteritis in Broiler Chickens: A Review on the Pathogen, Pathogenesis, and Prevention

et al. 2022

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“…A high efficiency of Aloe secundiflora crude extracts was demonstrated by inhibiting the development of A. galli eggs in vitro (Kaingu et al 2013 ). Stephen et al ( 2022 ) examined Sterospermum kunthianum (Cham-Holl) leaf extracts and their influence on in vitro A. galli egg development and found a concentration-dependency of the plant extract. Like ripleaf (Fayera et al 2018 ), Cham-Holl and A. secundiflora have tanniferous components which are known for their anthelmintic properties such as limiting the availability of nutrients for larvae, inhibiting oxidative phosphorylation in adults and larvae, binding to intestinal larval mucosae and causing thereby autolysis (Symeonidou et al 2018 ).…”

Section: Discussionmentioning

confidence: 99%

Pumpkin seeds, lemongrass essential oil and ripleaf leaves as feed additives for Ascaridia galli infected laying hens

et al. 2022

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The present study was performed to evaluate the in vivo efficiency of Curcurbita pepo (pumpkin) seeds, Cymbopogon citratus (lemongrass) essential oil and Plantago lanceolata (ripleaf) leaves against helminth infections in laying hens. In the first experiment, 75 Lohmann LSL Classic hens naturally infected with Ascaridia galli were assigned to groups of five; groups were randomly assigned to one of three treatments with five replicates each (untreated control; lemongrass oil: 1 g/bird/day; pumpkin seeds: 10 g/bird/day). Feed consumption and egg production were continuously recorded, individual faecal egg counts were determined weekly, and E. coli and Lactobacillus spp. three times during the experimental period of 29 days. After slaughter, intestinal worms were counted and sexed. Pumpkin improved feed conversion as compared to the control (p = 0.008) and to lemongrass (p = 0.021); no treatment effect on any other parameter was found. In the second experiment, 75 LSL pullets were artificially infected with 3 × 200 A. galli eggs, randomly divided into groups of five and assigned to one of three treatments (untreated control, lemongrass oil: 1 g/bird/day; ripleaf: 5% of ration). After 109 days of sampling as described above, hens were slaughtered and worm burdens determined. Performance of the animals did not change regardless of the treatment and none of the treatments resulted in changes of the microbiological and parasitological parameters. In conclusion, with the exception of improved feed conversion in the pumpkin group, no positive nor negative effects of the additives on performance, parasitological and microbiological parameters of naturally and artificially A. galli infected laying hens were observed.

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Evaluation of anthelmintic efficacy of ethanolic leaf extract of Juglans regia L. on Ascaridia galli: a comprehensive in vitro and in vivo study

Mir,

Tanveer,

Para

2024

Vet Res Commun

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In vitro and in vivo anthelmintic effects of Sterospermum kunthianum (Cham-Holl) leaf extract against Ascaridia galli in experimentally infected broiler chickens

Cited by 5 publications

References 14 publications

Necrotic Enteritis in Broiler Chickens: A Review on the Pathogen, Pathogenesis, and Prevention

Necrotic Enteritis in Broiler Chickens: A Review on the Pathogen, Pathogenesis, and Prevention

Pumpkin seeds, lemongrass essential oil and ripleaf leaves as feed additives for Ascaridia galli infected laying hens

Evaluation of anthelmintic efficacy of ethanolic leaf extract of Juglans regia L. on Ascaridia galli: a comprehensive in vitro and in vivo study

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