In Vitro and In Vivo Regulation of Erythropoiesis

Ganser, Arnold; Hoelzer, Dieter

doi:10.1007/978-3-642-83745-6_16

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1991

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“…Based on recent findings, it has been suggested that Epo can also affect target cells other than those of the erythroid lineage, such as megakaryocyte pre cursors (CFU-Meg), granulocyte-macrophage colony forming units (CFU-GM) and the pluripotent stem cell (CFU-GEMM) [26][27][28]; however, it is as yet un clear whether such a multilineage effect is direct or mediated by secondary factors.…”

Section: Introductionmentioning

confidence: 99%

Erythropoietin: Clinical Applications

Foa¹

1991

Acta Haematol

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The last few years have seen an enormous increase in our knowledge on the haematopoietic growth factor erythropoietin (Epo), firstly with its purification and determination of its primary amino acid sequence, and more recently with the isolation of the Epo gene and its expression in mammalian cell lines. This review article summarizes the crucial biological features of Epo and critically examines the main results obtained in clinical trials on humans.

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Section: Introductionmentioning

confidence: 99%

Erythropoietin: Clinical Applications

Foa¹

1991

Acta Haematol

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In Vitro and In Vivo Regulation of Erythropoiesis

Cited by 1 publication

References 53 publications

Erythropoietin: Clinical Applications

Erythropoietin: Clinical Applications

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