In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus

Cho, William C.; Leung, Kwok Nam

doi:10.1016/j.jep.2007.05.020

Cited by 216 publications

(119 citation statements)

References 24 publications

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“…This cure rate almost equaled 77.78% (14/18) rate reported by Martins-Carvalho et al (2010) who applied sialendoscopy to JRP by means of general anesthesia. Bear bile had a positive effect on smooth muscle contraction while Huangqi promoted secretions from the gland tissue as well as stimulated the immune system (Cho and Leung, 2007a;2007b;Liu et al, 2011). The cooperative use of bear bile and Huangqi, which unblocked the salivary duct and increased the secretions of saliva, can reconstruct the self-cleaning effect of the parotid gland.…”

Section: Rate (%)mentioning

confidence: 99%

“…Modern pharmacological research has shown that Huangqi preparation can enhance myocardial contractility, improve circulation, protect myocardial cells, and regulate immunity (Cho and Leung, 2007a;2007b;Fu et al, 2011;Liu et al, 2011). Bear bile, with its main pharmacological component ursodeoxycholic acid (UDCA, 3α,7β-dihydroxy-5β-cholan-24-oic acid), has been used in TCM for thousands of years.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach

Ruan

Huang

et al. 2013

J. Zhejiang Univ. Sci. B

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Abstract:Objective: To evaluate the pharmacological effects of traditional Chinese medicine, bear bile capsule and Huangqi granule, on recurrent parotitis in children. Methods: In this prospective, controlled, and randomized study, a total of 151 young children were divided into three groups: Group A included massaging the children's parotid region and melting vitamin C in their mouth daily; Group B included swallowing bear bile capsule and Huangqi granule daily; and Group C included massages and vitamin C as prescribed in Group A, and traditional Chinese medicine as prescribed in Group B. Children were treated individually for one month and then a follow-up study was conducted for 1 to 3.5 years. Analysis of variance (ANOVA) and Ridit analysis were employed for statistical analysis. Results: The recurrence rate decreased in every group, but was significantly more in Groups B and C when compared to Group A. The recurrences significantly decreased (P<0.01) in Group B and their recovery rate was as high as 63%, significantly better than those of the other groups (P<0.01). Conclusions: Huangqi and bear bile could be a novel clinical approach for treating recurrent parotitis in children.

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Section: Rate (%)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach

Ruan

Huang

et al. 2013

J. Zhejiang Univ. Sci. B

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“…Myelophil is a mixture of Astragali Radix and Salviae Radix extract representing Qi and blood, respectively, which support the liver and gastrointestinal system according to theories of Oriental medicine. Astragali Radix displays immunomodulating, hematopoietic, and anti-fibrotic properties [12][13][14] . Salviae Radix exhibits antioxidant, antiatherosclerosis, and antiplatelet aggregation pharmaceutical effects [15][16][17] .…”

Section: Introductionmentioning

confidence: 99%

Myelophil, a mixture of Astragali Radix and Salviae Radix extract, moderates toxic side effects of fluorouracil in mice

Shin¹,

Lee²,

Son³

et al. 2008

WJG

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“…mongholicus (Bunge) P.K.Hsiao, known as Meng Gu Huang Qi in Chinese, is a medicinal plant that has been widely used in China for thousands of years (Lui et al 2015). Currently, a. mongholicus is extensively utilised worldwide for its numerous medicinal properties, such as immune stimulant, tonic, antioxidant, hepatoprotectant, diuretic, antidiabetic, anticancer, and expectorant (Cho & Leung 2007;Agyemang et al 2013;Hong et al 2013;Shahzad et al 2016). Daodi herbs prove that herbs grown in some regions possess better quality and efficacy than those grown in other regions under certain natural, ecological, and environmental conditions.…”

mentioning

confidence: 99%

Discrimination of producing areas of Astragalus membranaceus using electronic nose and UHPLC-PDA combined with chemometrics

Wen-Long¹,

Li²,

Huang³

2017

Czech J. Food Sci.

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Wei W., Li J., Huang L. (2017): Discrimination of producing areas of astragalus membranaceus using electronic nose and UHPLC-PDA combined with chemometrics. Czech J. Food Sci., 35: 40-47.Electronic nose (E-nose) and ultra-high-performance liquid chromatography (UHPLC) were simultaneously developed for quality evaluation and diversity research of a. mongholicus. Instrumental data were subjected to principal component analysis (PCA) and discriminant factor analysis (DFA) to rapidly distinguish a. mongholicus derived from different main producing regions in China. E-nose results showed that a. mongholicus that originated from main producing areas (Gansu, Shanxi, and Inner Mongolia in China) could be accurately classified into three groups through PCA and DFA. The response values of samples from Inner Mongolia and Shanxi were similar, and better than those of the samples from Gansu. Identification by the E-nose was verified through UHPLC analysis, and the content of the main ingredient was consistent with the response value of a. mongholicus. In conclusion, E-nose and UHPLC combined with chemometrics can be used as reliable techniques to distinguish the geographic origins of a. mongholicus effectively, and evaluate the quality of traditional Chinese herbs.

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In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus

Cited by 216 publications

References 24 publications

Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach

Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach

Myelophil, a mixture of Astragali Radix and Salviae Radix extract, moderates toxic side effects of fluorouracil in mice

Discrimination of producing areas of Astragalus membranaceus using electronic nose and UHPLC-PDA combined with chemometrics

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