In vitro and in vivo corrosion, mechanical properties and biocompatibility evaluation of MgF 2 -coated Mg-Zn-Zr alloy as cancellous screws

Li, Zhen; Shizhao, Sun; Chen, Minfang; Fahlman, Bradley D.; Liu, Debao; Bi, Hongwei

doi:10.1016/j.msec.2017.02.168

Cited by 74 publications

(47 citation statements)

References 41 publications

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“…The binding energy of Mg1s peak is typical of magnesium in its oxidized form Mg 2+ [ 35 ]. The binding energies of F1s peak at 685.17eV (CG-MAO coating) and 685.07 eV (FG-MAO coating) demonstrate the presence of MgF 2 (685.4 eV) [ 36 , 37 ]. The Si2p peak at 102.07 eV (CG-MAO coating) and 102.27 eV (FG-MAO coating) are corresponding to MgSiO 3 (102.3 eV) [ 38 ].…”

Section: Resultsmentioning

confidence: 99%

Microstructure and Corrosion Behavior of Composite Coating on Pure Mg Acquired by Sliding Friction Treatment and Micro-Arc Oxidation

Cao

Huo

et al. 2018

Materials

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For the purpose of detecting the influence of grain structure of a Mg matrix on the microstructure and corrosion resistance of micro-arc oxidation (MAO) coating, prior to MAO processing, sliding friction treatment (SFT) was adopted to generate a fine-grained (FG) layer on coarse-grained (CG) pure Mg surface. It showed that the FG layer had superior corrosion resistance, as compared to the CG matrix, owing to the grain refinement; furthermore, it successfully survived after MAO treatment. Thus, an excellent FG-MAO coating was gained by combining SFT and MAO. The surface morphology and element composition of FG-MAO and CG-MAO samples did not show significant changes. However, the FG layer favorably facilitated the formation of an excellent MAO coating, which possessed a superior bonding property and greater thickness. Consequently, the modified FG-MAO sample possessed enhanced corrosion resistance, since a lower hydrogen evolution rate, a larger impedance modulus and a lower corrosion current were observed on the FG-MAO sample.

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Section: Resultsmentioning

confidence: 99%

Microstructure and Corrosion Behavior of Composite Coating on Pure Mg Acquired by Sliding Friction Treatment and Micro-Arc Oxidation

Cao

Huo

et al. 2018

Materials

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“…Following the ISO 10993-12 standard [35], the extraction medium of the samples was prepared by immersing the materials in the complete culture medium. After 24 h in the environment at 37 • C and 5% CO 2 , the solution was obtained and stored at 4 • C. Meanwhile, the L-929 cells were seeded on a 12-well culture plate with a density of 5 × 10 4 cells/mL to test their cytotoxicity [36]. These cells were cultured for 24 h and sufficiently adhered to the walls.…”

Section: In Vitro Cytocompatibility Evaluationmentioning

confidence: 99%

Preparation and Characterization of Fluoride-Incorporated Plasma Electrolytic Oxidation Coatings on the AZ31 Magnesium Alloy

Yang

Zhang

et al. 2019

Coatings

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In this study, films with different fluorine contents were prepared on an AZ31 magnesium alloy by using plasma electrolytic oxidation to study the corrosion resistance and cytocompatibility of the alloy. The morphology of the coating surface, phase, and chemical elements were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), and energy-dispersive X-ray spectrometry (EDS). The changes in the corrosion resistance with different fluorine contents were investigated by electrochemical experiments, hydrogen evolution, and long-term immersion tests. In addition, murine fibroblast L-929 cells were adopted for in vitro cytotoxicity tests using the cell counting kit (CCK)-8 assay, and the morphology of the cells was observed simultaneously by inverted microscopy. The results showed that the main form of the fluorine ions in the plasma electrolytic oxidation coatings was magnesium fluoride (MgF2). In addition, the corrosion resistance and cytocompatibilities of the coatings were improved by the addition of fluoride ions. When the content of potassium fluoride reached 10 g/L, the cell compatibility and corrosion resistance were the best, a finding which provides a basis for the clinical applications of the AZ31 magnesium alloy in the biomedical field.

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“…In this present work, Ca, Zr, Sr and Ag elements were added to the Mg-3Zn alloy to enhance its comprehensive properties on the basis of previous work [29][30][31], and the effects of these elements on the microstructure, mechanical properties and corrosion behavior of Mg-3Zn alloys were further investigated. The purpose of this study is to select an internal fracture fixation material with high biological safety and reliable performance and provide more experimental evidence for the development of new medical devices.…”

Section: Introductionmentioning

confidence: 99%

The Mechanical Properties and Corrosion Resistance of Magnesium Alloys with Different Alloying Elements for Bone Repair

et al. 2018

Self Cite

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In order to make a rational design of magnesium alloys for bone repair, four kinds of Mg alloy ingots were prepared by vacuum induction furnace, namely Mg-3Zn-0.2Ca (wt.%) (ZX30), Mg-3Zn-0.8Zr (wt.%) (ZK30), Mg-3Zn-0.8Zr-0.3Sr (wt.%) (ZKJ300) and Mg-3Zn-0.8Zr-0.3Ca-0.3Ag (wt.%) (ZKXQ3000) alloys. The four ingots were extruded into bar materials through a hot-extrusion process under different temperatures with different extrusion ratios, the mechanical performances and the corrosion behaviors in the simulated body fluid (SBF) of the four alloys were investigated, and the mechanism of fracture and corrosion was characterized by scanning electron microscopy (SEM). The results showed the ultimate compressive strength (UCS) of all the alloys were found to be around 360 MPa, while ultimate tensile strengths (UTS) of ZKJ300 (334.61 ± 2.92 MPa) and ZKXQ3000 (337.56 ± 2.19 MPa) alloys were much higher than those of ZX30 (298.17 ± 0.93 MPa) and ZK30 (293.26 ± 2.71 MPa) alloys. The electrochemical noise and immersion tests in the SBF indicated that ZK30 alloy performed better in corrosion resistance.

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In vitro and in vivo corrosion, mechanical properties and biocompatibility evaluation of MgF 2 -coated Mg-Zn-Zr alloy as cancellous screws

Cited by 74 publications

References 41 publications

Microstructure and Corrosion Behavior of Composite Coating on Pure Mg Acquired by Sliding Friction Treatment and Micro-Arc Oxidation

Microstructure and Corrosion Behavior of Composite Coating on Pure Mg Acquired by Sliding Friction Treatment and Micro-Arc Oxidation

Preparation and Characterization of Fluoride-Incorporated Plasma Electrolytic Oxidation Coatings on the AZ31 Magnesium Alloy

The Mechanical Properties and Corrosion Resistance of Magnesium Alloys with Different Alloying Elements for Bone Repair

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