In vitro anti-ageing activities of ethanolic extracts from Pink rambutan (Nephelium lappaceum Linn.) for skin applications

Boonpisuttinant, Korawinwich; Srisuttee, Ratakorn; Khongc, Heng Yen; Chutoprapat, Romchat; Ruksiriwanich, Warintorn; Udompong, Sarinporn; Chompoo, Wirinda; Boonbai, Rattiya; Rakkaew, Rattikarl; Sangsee, Jinapa; Sriprasert, Ketsani; Malilas, Waraporn

doi:10.1016/j.jsps.2023.02.006

Cited by 10 publications

(6 citation statements)

References 52 publications

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“…Several natural compounds abundantly found in vegetables and fruits that contain polyphenols (resveratrol, quercetin, curcumin, fisetin, apigenin, and luteolin) and non-polyphenols (berberine) have the potential to up-regulate SIRT1 and FOXO1 mRNA expression and activity, and to be considered for the prevention and treatment of stress-related oxidative diseases 12 , 13 , 47 . In comparison to my previous study, the GIG-S-M extract showed higher activation of SIRT1 mRNA, activation of FOXO1 mRNA than the pink rambutan seed extract prepared by maceration in 95% ethanol 31 . Studies have shown that flavonoids including quercetin can regulate a wide range of pathways by targeting the activity of SIRT1.…”

Section: Discussioncontrasting

confidence: 92%

“…All GIG extracts exhibited the highest dose-dependent levels of mushroom tyrosinase inhibition and also anti-melanogenesis on B 16 F 10 cells. These results are similar to the extract from Pink rambutan seeds from our the previous report 31 . The quercetin content of the GIG extracts may be responsible for inhibiting mushroom tyrosinase activity by binding to the active site of tyrosinase by hydrophobic interaction and chelating to copper ions with the 3′, 4′-dihydroxy groups, resulting in inhibition of the catalytic activity 34 .…”

Section: Discussionsupporting

confidence: 92%

“…Khan et al 30 reported that the P. emblica L. fruit extracts, which contain phenolic and flavonoid compounds, showed the free radical scavenging activity, lipid peroxidation and reducing power activity. In comparison to my previous study, the GIG-S-M extract showed higher free radical scavenging and lipid peroxidation activities, but lower metal chelating activity than the pink rambutan seed extract prepared by maceration in 95% ethanol 31 . Quercetin contents in the GIG extracts might also be responsible for the three anti-oxidative activities since they have the potential to prevent many oxidation reactions that relate to age-related dermatological ailments 23 , 32 .…”

Section: Discussioncontrasting

confidence: 88%

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Assessment of in vitro anti-skin aging activities of Phyllanthus indofischeri Bennet extracts for dermatological and aesthetic applications

Boonpisuttinant,

Taka,

Ruksiriwanich

et al. 2023

Sci Rep

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Giant Indian Gooseberry (GIG) or Phyllanthus indofischeri Bennet are commercially cultivated and commonly used herbs in Traditional medicine, especially in Thailand. The aim of this study was to assess the potential of the GIG extracts in anti-aging activities to be a dermatological application. The juice, meat residues, and seeds of GIG collected from Sra Kaeo Province, Thailand, were extracted by the Boiling method (B) and the Maceration process (M) by using 95% ethanol as a solvent. The GIG extracts gave the total phenolic, total flavonoid contents and quercetin contents, as well as exhibited anti-oxidative activities. The GIG-R-B extract inhibited tyrosinase activity and had the highest anti-melanogenesis activity on B16F10 cells at 31.63 ± 0.70%. The GIG-S-B, GIG-S-M, and GIG-R-M extracts demonstrated the highest collagen biosynthesis, which was comparable to vitamin C (p < 0.05), whereas the GIG-R-B extracts gave the highest stimulation of anti-aging genes (SIRT1 and FOXO1). All extracts at the concentration of 0.1 mg/mL showed no cytotoxicity on human skin fibroblasts. Therefore, the GIG-S-B extract was discovered to be a promising natural anti-aging agent for dermatological health and aesthetic applications that can be further developed in cosmetic, functional food and food supplement industries.

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Section: Discussioncontrasting

confidence: 92%

Section: Discussionsupporting

confidence: 92%

Section: Discussioncontrasting

confidence: 88%

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Assessment of in vitro anti-skin aging activities of Phyllanthus indofischeri Bennet extracts for dermatological and aesthetic applications

Boonpisuttinant,

Taka,

Ruksiriwanich

et al. 2023

Sci Rep

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“…Jantapaso and Mittraparp-Arthorn [70], evaluating aqueous extracts of fruit peels of Nephelium lappaceum L., another species of Sapindaceae, described an EC50 of 494.25 µg/mL for the DPPH assay, a value much higher than observed with T. esculenta. In addition [71], the EC50 values observed for the leaf and fruit peel extracts of Nephelium lappaceum concerning DPPH were 320 µg/mL and 35 µg/mL, respectively. These differences might be associated with the specific extraction methods, solvents used, and time of extraction [64,72].…”

Section: Discussionmentioning

confidence: 90%

“…Additionally, the study by [75] with Litchi chinensis Sonn (Sapindaceae) supported our results. However, the authors of [71] observed a cytotoxicity effect from the extracts obtained with Nephelium lappaceum leaves and fruit peels on human skin fibroblasts.…”

Section: Discussionmentioning

confidence: 99%

Exploring the Antioxidant Potential of Talisia esculenta Using In Vitro and In Vivo Approaches

da Silva Cordeiro,

de Queiroz Aquino-Martins,

da Silva

et al. 2023

Nutrients

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Medicinal plants, such as Talisia esculenta, are rich in antioxidant biomolecules, which are used in the treatment and prevention of many diseases. The antioxidant potential of T. esculenta extracts obtained from leaves and fruit peels was investigated using biochemical and 3T3 cell line assays as well as in vivo assays using an organism model Tenebrio molitor. Four extracts were tested: hydroethanolic extracts from leaves (HF) and from fruit peels (HC), and infusion extracts from leaves (IF) and from fruit peels (IC). The biochemical assays demonstrated an antioxidant capacity verified by TAC, reducing power, DPPH, and copper chelating assays. None of the extracts exhibited cytotoxicity against 3T3 cells, instead offering a protection against CuSO4-induced oxidative stress. The antioxidant activity observed in the extracts, including their role as free radical scavengers, copper chelators, and stress protectors, was further confirmed by T. molitor assays. The CLAE-DAD analysis detected phenolic compounds, including gallic acid, rutin, and quercitrin, as the main constituents of the samples. This study highlights that leaf and fruit peels extracts of T. esculenta could be effective protectors against ROS and copper-induced stress in cellular and invertebrate models, and they should be considered as coadjutants in the treatment and prevention of diseases related to oxidative stress and for the development of natural nutraceutical products.

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Biomass as Whitening Agents Derived from Plants

Ramadhan,

Maharani,

Devi

et al. 2024

Biomass-Based Cosmetics

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In vitro anti-ageing activities of ethanolic extracts from Pink rambutan (Nephelium lappaceum Linn.) for skin applications

Cited by 10 publications

References 52 publications

Assessment of in vitro anti-skin aging activities of Phyllanthus indofischeri Bennet extracts for dermatological and aesthetic applications

Assessment of in vitro anti-skin aging activities of Phyllanthus indofischeri Bennet extracts for dermatological and aesthetic applications

Exploring the Antioxidant Potential of Talisia esculenta Using In Vitro and In Vivo Approaches

Biomass as Whitening Agents Derived from Plants

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