In vitro anti-oxidant activity of Ruellia tuberosa root extracts

Chothani, Daya L.; Mishra, S.H.

doi:10.5530/ax.2012.4.7

Cited by 8 publications

(5 citation statements)

References 32 publications

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“…Hence, the attentions of investigators are turning to find out the natural antioxidants which are much safer and cheap. 3 Epidemiological studies have been reported that phytonutrients are beneficial in protecting human body against oxidative damage caused by free radicals. Therefore, increases the interest in isolation and characterization of plant-derived antioxidants.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Compound Quercetin-3-O-α-L-rhamnoside(1→6)- β-D-glucose (Rutin) isolated from ethyl acetate leaf extracts of Memecylon edule Roxb (Melastamataceae)

2015

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Introduction:The present study was aimed to isolate antioxidant principle from leaf ethyl acetate extract of Memecylon edule for the first time. M. edule belongs to melastomataceae family; possess various biological properties and folklore uses. Methods: Isolation of antioxidant compound was carried out by DPPH radicals scavenging activity guided method and employing chromatography techniques (TLC and column chromatography). The structure of isolated bioactive compound (Rutin) was confirmed by using various spectral data like UV, FT-IR, LC-MS, CHNS analysis, 1 H-NMR, 13 C-NMR, DEPT-135, HMBC and HSQC. In vitro antioxidant activity of isolated compound was evaluated by using DPPH radical, nitric oxide radical, superoxide radical, hydroxyl radical scavenging assays and ferric reducing antioxidant power assay (FRAP) with reference to ascorbic acid and butylated hydroxyanisole (BHA). One way analysis of variance (ANOVA) and Tukey's multiple comparison tests were performed. Results: DPPH activity guided isolation resulted isolation of Rutin. Isolated rutin exhibited remarkable scavenging capacity on all tested radicals in a concentration dependent manner. The results also showed that Rutin harbor strong reductive capacity on hydroxyl radicals with lowest IC 50 value (17.06 µg/ml) and strong ferric ion (Fe

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Section: Introductionmentioning

confidence: 99%

Antioxidant Compound Quercetin-3-O-α-L-rhamnoside(1→6)- β-D-glucose (Rutin) isolated from ethyl acetate leaf extracts of Memecylon edule Roxb (Melastamataceae)

2015

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“…Leaf extracts of R. tuberosa L. were reported to control lipid peroxide level and help strengthen antioxidant potential in diabetic rats (Manikandan et al, 2010). R. tuberosa root extracts displayed anti-oxidant activity, which were comparable with standards (Chothani and Mishra, 2012).…”

Section: Introductionmentioning

confidence: 59%

Composition of volatile oils from leaf, stem, root, fruit, and flower of Ruellia tuberosa L. (Acanthaceae) from Nigeria

Moronkola¹,

Aboaba²,

Choudhary³

2015

J. Med. Plants Res.

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We report composition of Ruellia tuberosa L. (Acanthaceae) leaf, stem, root, fruit, and flower volatile oils from Nigeria. The five volatile oils were obtained by hydro-distillation using all-glass Clevenger apparatus designed to British Pharmacoepia specifications and were procured in 0.09 to 0.36% yields. Each was separately examined using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) analysis. Our results revealed leaf oil contain 24 compounds, which make-up 86.95% of it; stem oil has 15 compounds (

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“…[156]. Many studies have verified that the extracts and compounds isolated from R. tuberosa exhibit a wide spectrum of pharmacological properties in vitro and in vivo, including cytotoxic [150,157], antioxidant [158][159][160][161], anticholinesterase [161], antimicrobial [162][163][164], insecticidal [164], antifertility [165], anthelmintic [166], antihyperlipidaemic, hepatoprotective [167], and antidiabetic activities [167][168]. Smilax zeylanica L.: S. zeylanica (Smilacaceae) is a medicinal plant widely growing in many parts of Myanmar.…”

Section: Millingtonia Hortensis Lf: M Hortensis a Member Of The Fmentioning

confidence: 99%

“…Sterculiaceae Whole plant cough, skin diseases, headache and as antihemorrhagic and antihypnotic [11] antihyperglycemic activity [146,148] 17. Ruellia tuberosa L. Acanthaceae Whole plant Antidote [15] Cytotoxicity [150,157], antioxidant [158][159][160][161], anticholinesterase [161], antimicrobial [162][163][164], insecticidal activity [164], antifertility [165], anthelmintic [166], antihyperlipidaemic, hepatoprotective [167], and antidiabetic activities [167][168]. 18.…”

Section: Stemona Burkilliimentioning

confidence: 99%

“…Moronkola et al studied the composition of volatile oils distilled from leaves, stems, roots, fruits, and flowers of R. tuberosa and reported that, among 109 identified constituents, (E)-phytol, tributylacetyl citrate, heptacosane, m-xylene, p-xylene, heptane, borneol, hexacosane, sexton, heneicosane, 2-methyl-2pentanol, and 1-methyl-1-cyclopentanol predominate [156]. Many studies have verified that the extracts and compounds isolated from R. tuberosa exhibit a wide spectrum of pharmacological properties in vitro and in vivo, including cytotoxic [150,157], antioxidant [158][159][160][161], anticholinesterase [161], antimicrobial [162][163][164], insecticidal [164], antifertility [165], anthelmintic [166], antihyperlipidaemic, hepatoprotective [167], and antidiabetic activities [167][168]. Smilax zeylanica L.: S. zeylanica (Smilacaceae) is a medicinal plant widely growing in many parts of Myanmar.…”

Section: Gaultheria Fragrantissimamentioning

confidence: 99%

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A Review of Common Medicinal Plants in Chin State, Myanmar

Thu¹,

Aye

Aung

et al. 2018

Natural Product Communications

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Promising sources of novel bioactive compounds include plants growing in several third-world countries where the local flora is still largely uninvestigated. A paradigmatic example is represented by medicinal plants growing in Myanmar, especially in Chin State, in northwestern Myanmar. This is one of the least developed areas of the country where the people still use natural remedies derived from a rich biodiversity. This review mainly covers the investigations done on phytochemical constituents and biological activities of 20 medicinal plants, namely Alangium chinense,

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In vitro anti-oxidant activity of Ruellia tuberosa root extracts

Cited by 8 publications

References 32 publications

Antioxidant Compound Quercetin-3-O-α-L-rhamnoside(1→6)- β-D-glucose (Rutin) isolated from ethyl acetate leaf extracts of Memecylon edule Roxb (Melastamataceae)

Antioxidant Compound Quercetin-3-O-α-L-rhamnoside(1→6)- β-D-glucose (Rutin) isolated from ethyl acetate leaf extracts of Memecylon edule Roxb (Melastamataceae)

Composition of volatile oils from leaf, stem, root, fruit, and flower of Ruellia tuberosa L. (Acanthaceae) from Nigeria

A Review of Common Medicinal Plants in Chin State, Myanmar

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