2010
DOI: 10.1016/j.bmc.2010.07.073
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In vitro anti-rotavirus activity of polyphenol compounds isolated from the roots of Glycyrrhiza uralensis

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Cited by 85 publications
(45 citation statements)
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“…They are increasingly being recognised for their nutritional value, since they may help reduce the risk of chronic disease and in general, have a positive effect on health (Tucker & Robards, 2008). They act as antioxidants, scavenge free radicals that induce vascular relaxation (del Alamo, Casado, Hernandez, & Jimenez, 2004) and they have been reported to have anti-inflammatory (Terra et al, 2007), anti-carcinogenic (Nichenametla, Taruscio, Barney, & Exon, 2006), anti-atherogenic, anti-thrombotic (Erlund et al, 2008), antimutagenic (Ferguson, 2001), antiviral (Kwon et al, 2010) and antibacterial (Tosi, Re, Ortega, & Cazzoli, 2007) properties.…”
Section: Introductionmentioning
confidence: 97%
“…They are increasingly being recognised for their nutritional value, since they may help reduce the risk of chronic disease and in general, have a positive effect on health (Tucker & Robards, 2008). They act as antioxidants, scavenge free radicals that induce vascular relaxation (del Alamo, Casado, Hernandez, & Jimenez, 2004) and they have been reported to have anti-inflammatory (Terra et al, 2007), anti-carcinogenic (Nichenametla, Taruscio, Barney, & Exon, 2006), anti-atherogenic, anti-thrombotic (Erlund et al, 2008), antimutagenic (Ferguson, 2001), antiviral (Kwon et al, 2010) and antibacterial (Tosi, Re, Ortega, & Cazzoli, 2007) properties.…”
Section: Introductionmentioning
confidence: 97%
“…However, most of the time, antimicrobial activity is solely tested against bacteria, yeast, and molds. In contrast, reports on the antiviral effects of plant extracts are rather limited (16,26,31).…”
mentioning
confidence: 99%
“…Those fractions were purified by preparative TLC on silica gel or by preparative HPLC to give isolicoflavonol (7) [22], isoglycycoumarin (8) [23], licoarylcoumarin (9) [24], formononetin (10) [25], and 6"-O-acetylliquiritin (11) [26]. On the other hand, the remaining part of the ethyl acetate fraction was directly subjected to column chromatography on ODS-gel, and fractions from the column were further purified by column chromatography on MCI-gel CHP-20P, and by preparative HPLC or preparative TLC, to give liquiritin (12) [27], p-hydroxybenzoic acid (13), semilicoisoflavone B (14) [28], glycyrol (15) [29], glycyrin (16) [29], gancaonin I (17) [30], isoglycyrol (18) [31], liquiritigenin (19) [27], gancaonin G (20) [36], glicoricone (25) [37], glycycoumarin (26) [38], licocoumarone (27) [29], licoricone (28) [39], glyasperin D (29) [40], isoangustone A (30) [41], and two additional compounds temporarily named compounds A (31), and B (32). Since several phenolics from licorice display potent antibacterial effects against methicillin-resistant Staphylococcus aureus (MRSA), and also show suppressing effects on the oxacillin resistance of MRSA, as we have reported previously [11], we have also investigated the effect of these licorice phenolics on VRE.…”
Section: Resultsmentioning
confidence: 99%