In vitro anticancer activity of Pd(II) complexes with pyridine scaffold: Their bioactivity, role in cell cycle arrest, and computational study

Transition Metal-Decorated B12N12–X (X = Au, Cu, Ni, Os, Pt, and Zn) Nanoclusters as Biosensors for Carboplatin

“…It is the difference observed between the reactant and product of the reaction. Generally, according to literature reviews, when Δ H > 0, the reaction is termed endothermic, meaning that the heat is absorbed from the surrounding to form the product . Meanwhile, when Δ H < 0, it is termed exothermic, which is when heat or energy is released to the surrounding. , Utilizing the data obtained after optimization, the enthalpy of all the reactions was being calculated in these studies using eqs and . normalΔ H * .25em ( 298 K ) = prefix∑ normalΔ normalf H * normalp normalr normalo normald false( 298 normalK false) − prefix∑ normalΔ normalf H * normalr normale normala normalc normalt false( 298 normalK false) normalΔ normalf H * .25em ( 298 K ) = prefix∑ false( ε 0 + H normalc normalo normalr normalr false) normalp normalr normalo normald normalu normalc normalt − prefix∑ false( ε 0 + H normalc normalo normalr normalr false) normalr normale…”

“…Generally, according to literature reviews, when Δ H > 0, the reaction is termed endothermic, meaning that the heat is absorbed from the surrounding to form the product. 72 Meanwhile, when Δ H < 0, it is termed exothermic, which is when heat or energy is released to the surrounding. 73 , 74 Utilizing the data obtained after optimization, the enthalpy of all the reactions was being calculated in these studies using eqs 19 and 20 .…”

“…It is the difference observed between the reactant and product of the reaction. Generally, according to literature reviews, when Δ H > 0, the reaction is termed endothermic, meaning that the heat is absorbed from the surrounding to form the product . Meanwhile, when Δ H < 0, it is termed exothermic, which is when heat or energy is released to the surrounding. , Utilizing the data obtained after optimization, the enthalpy of all the reactions was being calculated in these studies using eqs and . where ε 0 represents electronic energy and H corr is the sum of electronic energy and thermal correction to H .…”

Synthesis, Characterization, Photoluminescence Properties and Antiproliferative Activity of New Pd(II), Ni(II) and Cu(II) Mixed Complexes Bearing Schiff Base Ligand and 1,10‐phenanthroline

“…[29,30] Pd(II) complexes' ability to inhibit cellular target DNA's fast replication and ultimately lead to cell death is what underlies their anticancer effect. [31,32] Recently, the mixed ligand Ni(II) complexes have displayed a variety of biological activities, such as antiproliferative and anticancer properties. [33] Previous studies have concluded that the capacity of certain Ni compounds to interact with DNA and generate DNA damage resulted in a reduction in the growth of cancer cells.…”

“…Compounds with a wider range of bioactivity may be produced by systematic structural modification of the carrier ligands with the heteroaromatic π‐electron system, tailoring groups with labile sulfur‐containing amino acids, or oxygen donor scaffolds connected to Pd(II) metal [29,30] . Pd(II) complexes′ ability to inhibit cellular target DNA′s fast replication and ultimately lead to cell death is what underlies their anticancer effect [31,32] . Recently, the mixed ligand Ni(II) complexes have displayed a variety of biological activities, such as antiproliferative and anticancer properties [33] .…”