In vitro anticancer, antimicrobial and antiradical properties and bioactive compounds of endemic Wiedemannia orientalis Fisch. & Mey. flowers

Abstract

W. orientalis is a one-year herbaceous plant, located in the Lamiaceae family, and is called Ballıbaba in Turkish. In the presented study, the antimicrobial and anticancer properties of flowers extracts of endemic W. orientalis were investigated for the first time. Also, it was investigated the antiradical activity and phytochemical contents of this plant extracts. According to our study results, endemic W. orientalis flowers extract show very high anticancer activity against MCF-7, HCT-116 and LNCaP cancer cell lines, high antiradical activity against ABTS radicals, and effective antimicrobial activity against some microorganism caused infection in humans. In conclusion, endemic W. orientalis can be used as an anticancer and antimicrobial agent and this plant can be the subject of further studies in the field of herbal medicine.

Effects of fermentation, boiling, and drying methods on bioactive properties, phenolic and nutrient profiles of aerial parts of purslane (Portulaca oleracea L.) plants

“…Results were found low when compared to the studies carried out byUddin et al, (2014),Keser et al, (2021) andYoussef & Mokhtar (2014). In addition, findings on total phenol in purslane were higher than those ofMercadante & Rodriguez-Amaya (1990) andDesta & Cherie (2018).…”

“…The aerial parts of purslane plants are rich in apigenin, kaempferol, luteolin, quercetin, myricetin, genistein, caffeic, chlorogenic, pcoumaric, ferulic and rosmariniz acids, lignins, stilbenes (Erkan, 2012;Yan et al, 2012;Zhou et al, 2015). The findings obtained showed partial differences in phenolic component values of purslane samples compared to the results of previous studies (Silva & Carvalho, 2014;Ai et al, 2015;Keser et al 2021). These differences can be likely due to extraction and solvent types, fermentation, boiling, drying systems and harvest time of purslane plants.…”

“…The total flavonoid and phenolic results of methanol extracts of P. oleraceae were determined as 1317.41 μgCE/g and 75.96 mgGAE/g extract, respectively (Keser et al ., 2021). Uddin et al ., (2014) and Keser et al ., (2021) reported that P. oleraceae methanol extracts have 76.71% and 47.13% DPPH radical scavenging capacity, respectively. Total phenolic, flavonoid and antioxidant capacity results of the fresh purslane leaves were 1447.59 mg GAE/100 g, 5011.87 mg QE/100 g (dw) and 53.23% DPPH radical scavenging capacity, respectively (Youssef & Mokhtar, 2014).…”

“…Desta & Cherie (2018) determined 4.9029 mg GAE/g total phenol and 1.357 mg QE/100 g total flavonoid in methanol extracts of Purslane quadrifida . The total flavonoid and phenolic results of methanol extracts of P. oleraceae were determined as 1317.41 μgCE/g and 75.96 mgGAE/g extract, respectively (Keser et al ., 2021). Uddin et al ., (2014) and Keser et al ., (2021) reported that P. oleraceae methanol extracts have 76.71% and 47.13% DPPH radical scavenging capacity, respectively.…”

“…Total phenolic, flavonoid and antioxidant capacity results of the fresh purslane leaves were 1447.59 mg GAE/100 g, 5011.87 mg QE/100 g (dw) and 53.23% DPPH radical scavenging capacity, respectively (Youssef & Mokhtar, 2014). Results were found low when compared to the studies carried out by Uddin et al ., (2014), Keser et al ., (2021) and Youssef & Mokhtar (2014). In addition, findings on total phenol in purslane were higher than those of Mercadante & Rodriguez‐Amaya (1990) and Desta & Cherie (2018).…”