In vitro Antimicrobial Activity of Some Commercial Toothpastes

Teke, Gerald Ngo; Enongene, Ngolle Godwill; Tiagha, Akah Roland

doi:10.20546/ijcmas.2017.601.052

Cited by 6 publications

(6 citation statements)

References 22 publications

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“…The mixtures were then filtered and subsequently oven dried at 60 degrees for three hours. Six sample groups were used in this experiment, five containing eggshell powder and dissolved toothpaste (test groups), while the sixth, eggshell powder dissolved in 100 cm 3 deionised water, was used as the control group. Energy dispersive x-ray spectroscopy in conjunction with a scanning electron microscope (Field Emission-Carl Zeiss), operating at controlled atmospheric conditions at 20 kV, were used to determine the elemental composition of the samples and to examine the surface morphology.…”

Section: Glaxosmithklinementioning

confidence: 99%

“…Dental caries, also known as tooth decay, is a common bacterial disease characterised by demineralisation and destruction of hard tissues, usually by the production of acid by bacterial fermentation of undisturbed food debris which has accumulated on the tooth surface. [1][2][3] Despite the global improvement in oral health status, Inetianbor et al 4 point out that dental caries remains one of the most chronic and prevalent infectious diseases in the world. 1,5,6 Although dental caries has multifactorial causes, 1 the dietary lifestyles of the individual 2 as well as sub-optimal oral hygiene habits 7 help facilitate the onset of this disease.…”

Section: Introductionmentioning

confidence: 99%

“…But just how effective they actually are remains a question since the continued prevalence of dental caries is still a public health concern. 3 Thus, it is desirable to evaluate the claims that these commercial toothpastes completely prevent the acid attacks that result in caries.…”

Section: Introductionmentioning

confidence: 99%

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An in vitro examination on the effectiveness of commercial toothpastes in the prevention of tooth decay, using eggshell as a substitute for human tooth material

et al. 2018

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Background: Despite improvements in oral health status, dental caries remains a public concern. This study examines the effectiveness of commercial toothpastes in the prevention of tooth decay, using eggshell powder as a substitute for human tooth material. Methods: Colgate, Aquafresh, Colgate Sensitive, Sensodyne, and Oralwise were tested. An enamel model was simulated by adding eggshell powder to beakers containing dissolved toothpastes. The contents were agitated for eight hours at 800rpm, filtered and oven dried. Scanning Electron Microscope (SEM) and Energy Dispersive Spectroscopy (EDX) were used to characterise the surface morphology and the calcium and phosphate composition of the toothpastes pre-and post-agitation with eggshell powder. Gas-displacement and pressure sensor tests evaluated the rate of reaction between the substitute "tooth enamel" and acids. results: EDX analysis confirmed the presence of calcium phosphate ions, while SEM revealed the formation of an enamel-like layer after agitation. Pressure sensor tests confirmed Colgate Sensitive as most effective in protection against acid attacks, with Oralwise least effective. conclusions: Eggshell can be used as a substitute for the human tooth in an in vitro experiment. All the tested brands of toothpaste effectively reduced the acid reaction, which would contribute to the prevention of tooth decay.

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Section: Glaxosmithklinementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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An in vitro examination on the effectiveness of commercial toothpastes in the prevention of tooth decay, using eggshell as a substitute for human tooth material

et al. 2018

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“…Our results using 0.12% chlorhexidine demonstrated an inhibition zone with an average size of 20.2 mm, which is in the range observed in these studies. Many commercial toothpastes have demonstrated inhibitory effects against P.gingivalis, which is a common pathogen for oral diseases [ 22 , 23 ]. Similarly, the herbal toothpaste formulae demonstrated an inhibition zone.…”

Section: Discussionmentioning

confidence: 99%

The efficiency of natural wound healing and bacterial biofilm inhibition of Aloe vera and Sodium Chloride toothpaste preparation

Vajrabhaya

Korsuwannawong

Ruangsawasdi

et al. 2022

BMC Complement Med Ther

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Background Prevention is a preliminary focus of periodontitis treatment. Rather than giving complicated treatment to a periodontitis patient, a variety of toothpastes have been suggested to prevent periodontal disease progression. Herbal toothpastes containing natural plant components for maintaining or increasing healing might be a treatment modality for improving oral hygiene. Aloe vera is a medicinal plant with active ingredients that have antioxidant and anti-inflammatory effects. Additionally, increased sodium in the environment inhibits microorganism growth. A toothpaste containing salt and aloe vera may be an option to provide good oral hygiene. Aim To assess the in vitro cell migration of human gingival fibroblasts and antimicrobial effects of an herbal toothpaste containing A. vera and Sodium chloride. Methods The cytotoxicity of 0.02% or 0.2% toothpaste solution on human gingival fibroblast cell line was evaluated using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. The cell migration after treatment with 0.2% (v/v) toothpaste was determined using a Boyden Chamber assay. The effect of the toothpaste on inhibiting Porphylomonas gingivalis planktonic and biofilm growth was compared with Chlohexidine (CHX) using a Disk Diffusion and Biofilm susceptibility test, respectively. The results of the cytotoxicity assay, inhibition zone and percentage of live cells in the biofilm were statistically analyzed with One-way analysis of variance. Cell migration and biofilm inhibition were evaluated using the independent sample t-test and multiple t-test, respectively (p = 0.05). Results Neither test concentration of the toothpaste solution was toxic to the target cells. The 0.2% concentration was selected for the cell migration experiment. The herbal toothpaste formulation significantly increased cell migration compared with the control group (culture medium) (p = .02) The antimicrobial effect of this formulation on the P. gingivalis planktonic form was lower compared with 0.12% CHX (positive control group), however, it demonstrated greater P. gingivalis biofilm formation inhibition compared with the 0.12% CHX group. Conclusions The alternative use of an herbal toothpaste instead of a non-herbal toothpaste formulation should be considered for promoting oral health care. However, further clinical studies are necessary before it can be considered for patient use.

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“…Recently published study reported that after the five years use of triclosan containing toothpaste did not develop triclosan-resistant bacteria [17,18] Therefore purpose behind this study was to evaluate the, comparative effect between two ingredient triclosan and sodium monofluorophosphate on plaque reduction.…”

Section: Broad-spectrum Phenolic Biocides Triclosanmentioning

confidence: 99%

Effect of Triclosan and Sodium Monofluorophosphate on Plaque Reduction

Soomro

Banglani

Memon

et al. 2021

JPRI

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Objective: The aim of the study is to compare the clinical efficacy between two ingredient Triclosan and sodium monofluorophosphate on plaque accumulation. Material and Methodology: This cross section study was carried out in school (Govt Girls High School Kotri). Total 100 school children were selected, between age ranges 13–16 years, which were divided in to two groups (group A & B) according to dentifrice given. Group A: Toothpaste containing the active ingredient 0.3% Triclosan. Group B: Toothpaste containing 0.8% sodium monofluorophosphate. All patients were examined clinically for assessment using the Plaque index (PI) at follow up periods every week. Plaque was evaluated by using the silness-loe index. Oral examination for dental plaque assessment was carried out at the start of the study and the children were follow up to 10 weeks. Data were analyzed by SPSS 16 version and one-way ANOVA test. Result: Triclosan toothpaste users experienced significant reduction in plaque accumulation as compared to the sodium monofluorophosphate toothpaste users. Conclusion: At 3-weeks, Triclosan provided statistically signiﬁcantly greater reductions than sodium monofluorophosphate in plaque reduction.

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In vitro Antimicrobial Activity of Some Commercial Toothpastes

Cited by 6 publications

References 22 publications

An in vitro examination on the effectiveness of commercial toothpastes in the prevention of tooth decay, using eggshell as a substitute for human tooth material

An in vitro examination on the effectiveness of commercial toothpastes in the prevention of tooth decay, using eggshell as a substitute for human tooth material

The efficiency of natural wound healing and bacterial biofilm inhibition of Aloe vera and Sodium Chloride toothpaste preparation

Effect of Triclosan and Sodium Monofluorophosphate on Plaque Reduction

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