In vitro Antimicrobial Activity of Fruit Pulp Extracts of Azanza garckeana (F. Hoffm.) Exell &amp; Hillc. and Isolation of One of its Active Principles, Betulinic Acid

Dikko, Y; Khan, Muluh Emmanuel; Tor-Anyiin, T. A.; Anyam, J.V.; Linus, U

doi:10.9734/bjpr/2016/30152

Cited by 26 publications

(25 citation statements)

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“…It has been reported earlier that ethyl acetate has high extraction capacity for flavonoids, tannins, alkaloids and saponins which had been adjudged to have high antimicrobial activities. 31 In a related study, Dikko et al 32 further observed that the ethyl acetate fraction of their endophytic metabolites showed higher antimicrobial activities against their test 1, clearly depicts susceptibility of the test bacteria to the endophytic fungal metabolites. In figure 1 A-C, the RT1 and MR1 extracts produced more inhibition against ESβL than VRSA.…”

Section: Resultsmentioning

confidence: 94%

Susceptibility Studies of Vancomycin Resistant Staphylococcus aureus (VRSA), Extended ?-lactamase Producing Escherichia coli and P. falciparum to Ethylacetate Extract of Endophytic Fungal Metabolites from Annona senegalensis

2021

TJNPR

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Section: Resultsmentioning

confidence: 94%

Susceptibility Studies of Vancomycin Resistant Staphylococcus aureus (VRSA), Extended ?-lactamase Producing Escherichia coli and P. falciparum to Ethylacetate Extract of Endophytic Fungal Metabolites from Annona senegalensis

2021

TJNPR

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“…This could be due to ethylacetate's greater extraction capacity, enabling it to extract more bioactive compounds responsible for the observed antimicrobial activity. Dikko et al, 26 and Okokon et al, 27 had also reported that ethyl-acetate fractions exhibit more excellent antimicrobial activity compared to other fractions. However, despite the higher zone of inhibition demonstrated by the ethyl-acetate fraction of Sarcocephalus latifolius, the zones of inhibitions were lower on all test organisms compared to the zone of inhibitions demonstrated by standard antimicrobial drug (ciprofloxacin/fluconazole) used as a positive control in this study.…”

Section: Resultsmentioning

confidence: 96%

Antimicrobial Activity, Phytochemistry and Acute Toxicity Profile of Sarcocephalius latifolius Root Bark

2021

TJNPR

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Medicinal plants have been a source of medicinal agents for many years, and many chemotherapeutic drugs have their origin from plants. 1 The world health Organization (WHO) stated that medicinal plants are the best precursors for synthesizing new drugs. 2 In recent times, there is an increase in plant-based therapeutic products in both developed and developing countries because they are mostly nontoxic, have fewer side effects, and are available at affordable prices. 3 Medicinal plants are used widely in many parts of the world, especially in rural areas with limited access to modern medical and health facilities. 4 Even though orthodox medicines are now available for many debilitating ailments and disease conditions, there is a need to develop new therapeutic antimicrobial agents from medicinal plants due to the increasing toxicity and failure of many chemotherapeutics and antibiotics resistance exhibited by pathogenic microorganisms. [5][6][7] Medicinal plants have also been reported to have minimal or no side effects and have been found useful for practically almost every known ailment. Sarcocephalus latifolius (Smith), also called African peach, is a member of the plant family Rubiaceae. The plant is a small multistemmed tree with rounded-ovate leaves and bears red ball-like fruits. 8 The plant is widely distributed in several African countries, including, but not limited to,

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“…The test-tubes were incubated for 18hours at 37 0 C for bacteria and for 48 hours at 30 0 c for the fungi. The obtained microorganisms in the broth were standardized using normal saline to obtain a population density of 100cfu/mL for the bacteria, [23].…”

Section: Preparation Of Inoculummentioning

confidence: 99%

Synthesis, Spectroscopic Characterization and Biological Studies of 2-{[(2-Hydroxy-5-Methoxyphenyl) Methylidene] Amino} Nicotinic Acid and Its Manganese (Ii) Complexes

Osigbemhe¹,

Khan²,

Oviawe³

et al. 2021

JCSN

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Manganese(II) complexes of 2-{[(2-hydroxy-5-nitrophenyl) methylidene]amino} nicotinic acid derived from o-phenylenediamine and 5- nitrosalicaldehyde were synthesized and characterized by elemental analysis, using IR, 1HNMR, 13CNMR, and GCMS. They were screened against known disease causative microbes to establish their potentials as antimicrobial agents compared with national standards drugs. Results showed that, a Schiff base exhibited antimicrobial action against all the bacteria and most of the fungi with exception of Candidas. albicans isolate, which exhibited zero diameter zone of inhibition. It was also found that the synthesized Schiff base exhibited two digits purity range, implying that it was relatively stable. The metal complex was found to be more susceptible in overall biological activity due to the structural stability, showing their potency in pharmacognocy.

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In vitro Antimicrobial Activity of Fruit Pulp Extracts of Azanza garckeana (F. Hoffm.) Exell & Hillc. and Isolation of One of its Active Principles, Betulinic Acid

Cited by 26 publications

References 0 publications

Susceptibility Studies of Vancomycin Resistant Staphylococcus aureus (VRSA), Extended ?-lactamase Producing Escherichia coli and P. falciparum to Ethylacetate Extract of Endophytic Fungal Metabolites from Annona senegalensis

Susceptibility Studies of Vancomycin Resistant Staphylococcus aureus (VRSA), Extended ?-lactamase Producing Escherichia coli and P. falciparum to Ethylacetate Extract of Endophytic Fungal Metabolites from Annona senegalensis

Antimicrobial Activity, Phytochemistry and Acute Toxicity Profile of Sarcocephalius latifolius Root Bark

Synthesis, Spectroscopic Characterization and Biological Studies of 2-{[(2-Hydroxy-5-Methoxyphenyl) Methylidene] Amino} Nicotinic Acid and Its Manganese (Ii) Complexes

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