In vitro antimicrobial activity of ethanol and water extracts of Cassia alata

Somchit, M. N.; ., I. Reezal; Nur, Indriyani; Mutalib, AR

doi:10.1016/s0378-8741(02)00146-0

Cited by 160 publications

(97 citation statements)

References 5 publications

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“…Other researchers have also assessed the antibacterial efficacy of ethanolic extract of A. indica. 25,26 Assessment has also been performed on the prophylactic activities of A. indica with several extracts such as methanol, acetone, chloroform, petroleum ether, and n-hexane. 27 Findings in this previous study were similar to those in the present study.…”

Section: Discussionmentioning

confidence: 99%

Insights into the in vitro germicidal activities of Acalypha indica

Rahman¹,

Hossain²,

Saikot³

et al. 2017

Analytical Science and Technology

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Background and purpose: This study was carried out to learn more about the potential prophylactic or antibacterial activity of the plant Acalypha indica against selective pathogenic bacteria. Experimental: The test organisms were Sarcina lutea IFO 3232, Bacillus subtilis IFO 3026, Pseudomonas denitrificans, Escherichia coli IFO 3007, Klebsiella pneumoniae ATTC 10031, Xanthomonas campestris IAM 1671, and Proteus vulgaris.Leaf, stem, and bud powder of Acalypha indica were dissolved in various solvents, and the extracts were tested for antimicrobial activity through the disc diffusion method. GC-MS profiling was performed to characterize active chemical compounds in the essential oil of Acalypha indica. Results: The ethanol extract showed the highest activity against all bacteria, while the petroleum ether extract yielded the highest zone of inhibition against Proteus vulgaris (11.83 ± 1.75 mm). The minimum inhibitory concentration (MIC) of the ethyl acetate extract against Bacillus subtilis was 16 µg/mL. Phytochemical screening by GC-MS revealed a total of 12 bioactive compounds. Conclusion:Extracts of Acalypha indica may be useful in formulating and synthesizing new antibacterial drugs.

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Section: Discussionmentioning

confidence: 99%

Insights into the in vitro germicidal activities of Acalypha indica

Rahman¹,

Hossain²,

Saikot³

et al. 2017

Analytical Science and Technology

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“…Viana et al (2008) enfatizam que atividade antifúngica de extratos de plantas pode estar influenciada pelo ambiente ao qual a planta foi submetida, a fatores genéticos, a utilização de diferentes métodos de extração, ao pH, a temperatura e ao uso de diferentes concentrações. Vários trabalhos mostram que o uso de diferentes concentrações pode interferir nos resultados obtidos em experimentos onde foram utilizadas as mesmas espécies vegetais (Ranganathan & Balajee, 2000;Somchit et al, 2003).…”

Section: Diâmetro Das Colôniasunclassified

“…A dermatofitose é, comparativamente, uma condição clínica comum tanto em animais de companhia como em animais de criação (Tortora et al, 2002;Hirsh & Zee, 2003;Quin et al, 2005). As dermatofitoses podem ser transmitidas de animal para animal, de animal para seres humanos, ou do solo para os animais e para os seres humanos (Minami, 2003).…”

Section: Introductionunclassified

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Avaliação in vitro da atividade antifúngica de extratos de plantas e óleo de eucalipto sobre Trichophyton mentagrophytes

Frias

D²

2009

Rev. bras. plantas med.

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RESUMO:O presente estudo teve como objetivo determinar a ação antifúngica de extratos de plantas medicinais e óleo de eucalipto frente ao dermatófito Trichophyton mentagropytes, visando a utilização da fitoterapia no controle. As plantas utilizadas na obtenção dos extratos foram arruda (Ruta graveolens), citronela (Cymbopogon nardus), cravo de defunto (Tagetes minuta), eucalipto (Eucalyptus spp), graviola (Annona muricata), fruta do conde (Annona spp), manga (Mangifera indica), romã (Punica granatum), flores e folhas de primavera (Bougainvillea spectabilis). Verificou-se que uso de 0,5% óleo de eucalipto no combate ao T. mentagropytes foi eficaz, já os extratos de citronela (4%) eucalipto (5%) e romã (8%) atuaram como fungistáticos e os restantes não devem ser usados contra este dermatófito porque não causaram nenhum efeito. Palavras-chave:Trichophyton mentagropytes, dermatófito, óleo de eucalipto, plantas medicinais ABSTRACT: In vitro evaluation of the antifungal activity of plant extracts and eucalyptus oil on Trichophyton mentagrophytes. The aim of this study was to assess the antifungal action of medicinal plant extracts and eucalyptus oil against the dermatophyte Trichophyton mentagrophytes in order to employ phytotherapy for its control. The plants used for extract production were common rue (Ruta graveolens), citronella (Cymbopogon nardus), wild marigold (Tagetes minuta), eucalyptus (Eucalyptus spp), sweetsop (Annona muricata), custard apple (Annona spp), mango (Mangifera indica), pomegranate (Punica granatum), besides flowers and leaves of bougainvillea (Bougainvillea spectabilis). The use of 0.5% eucalyptus oil was effective in controlling Trichophyton mentagrophytes; however, citronella (4%), eucalyptus (5%) and pomegranate (8%) extracts acted as fungistatic, and the remaining extracts should not be used against this dermatophyte since they did not have any effect.

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“…In Suriname, root extracts from C. alata are used for the treatment of uterus disorders [1]. Pharmacological investigations performed so far on C. alata have shown that this herb has several biological activities, such as antimicrobial [8,9], antifungal [2,10,11], purgative [4], anti-inflammatory [11,12], analgesic [1,11,13], antitumor [14], and hypoglycaemic [11] activities.…”

Section: Published In Final Edited Form Asmentioning

confidence: 99%

Determination of pharmacologically active compounds in root extracts of Cassia alata L. by use of high performance liquid chromatography

Fernand

Dinh

Washington

et al. 2008

Talanta

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A simple high performance liquid chromatography (HPLC) method was developed and validated for the determination of six phenolic compounds, five anthraquinones (rhein, aloe-emodin, emodin, chrysophanol and physcion) and a flavonoid (kaempferol), in root extracts from Cassia alata L. Solid-phase extraction, using C 18 cartridges, was used to remove interfering substances from the root extracts. The extracts were analyzed on a C 18 column using an isocratic mobile phase which consisted of acetonitrile, methanol, and 10 mM aqueous ammonium acetate (25: 55: 20, v/v). Identification of the analytes was performed by use of standards and on-line mass spectrometric detection using atmospheric pressure chemical ionization. The concentration of the phenolic compounds in the root extracts was determined using HPLC with ultraviolet detection at 260 nm. The limits of detection obtained for the anlytes were in the range of 0.23 -4.61 ppm. The overall R.S.D. precision values (intra and inter-day) for the retention times and peak-areas were lower than 0.16% and 2.10%, respectively. In addition, the recovery of the developed method for the analysis of these phenolic compounds was determined, and ranged from 81.2 ± 4.3% to 106 ± 2%.

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In vitro antimicrobial activity of ethanol and water extracts of Cassia alata

Cited by 160 publications

References 5 publications

Insights into the in vitro germicidal activities of Acalypha indica

Insights into the in vitro germicidal activities of Acalypha indica

Avaliação in vitro da atividade antifúngica de extratos de plantas e óleo de eucalipto sobre Trichophyton mentagrophytes

Determination of pharmacologically active compounds in root extracts of Cassia alata L. by use of high performance liquid chromatography

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