In vitro antimicrobial effect of different root canal sealers against oral pathogens

Monajemzadeh, Ali; Ahmadi, Sina; Aslani, Sajad; Sadeghi-Nejad, Batool

doi:10.29252/cmm.3.2.7

Cited by 14 publications

(10 citation statements)

References 37 publications

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“…(EndoREZ) con medidas muy inferiores. Monajemzadeh et al (2017), encontraron que el cemento a base de resina (AH 26) fue el de mejor actividad antimicrobiana contra C. albicans (26 mm) mientras que el de ZnO + Eugenolno fue capaz de inhibir su crecimiento; en el caso de S. mutans obtuvo resultados iguales entre ambos cementos (20 mm). En nuestro estudio se observaron resultados similares a los de Bhargava et al contra C. albicans, siendo el cemento a base de ZnO + Eugenol (Endofill) en cemento con mayor poder de inhibición del crecimiento fúngico (21,965 mm).…”

Section: Discussionunclassified

Efecto Antimicrobiano de Tres Cementos Selladores Endodónticos frente a Streptococcus mutans, Enterococcus faecalis y Candida albicans

Chambilla-Torres

Sánchez-Tito

2021

Int. J. Odontostomat.

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RESUMEN:El objetivo del estudio fue evaluar el efecto antimicrobiano de tres cementos selladores endodónticos frente a Streptococcus mutans, Enterococcus faecalis y Candida albicans. Se usó el método de difusión en agar, realizando pozos de 5 mm de diámetro por 4 mm de profundidad, en donde se colocaron los diferentes cementos que fueron preparados según las indicaciones del fabricante. Para S. mutans y E. faecalis se empleó agar cerebro-corazón, mientras que para C. albicans se empleó agar tripticasa soya como medios de cultivo. Las placas fueron incubadas por 48 horas a 37 ºC. Los halos de inhibición de crecimiento microbiano se midieron con un compás Vernier. Los resultados mostraron diferencias significativas entre todos los grupos p < 0,05. El cemento a base de óxido de zinc y eugenol (Endofill) mostró el mejor efecto antimicrobiano contra las tres cepas con halos de inhibición de 23,283 ± 5,497 mm para S. mutans, 8,468 ± 0,755 mm para E. faecalis y 21,965 ± 1,187 mm para C. albicans. Mientras que el cemento a base de resina (Vioseal) tuvo una actividad similar a Endofill solo para S. mutans (21,262 ± 2,602 mm) (p > 0,05), siendo bastante inferior para E. faecalis (6,642 ± 0,659 mm) y C. albicans (8,781 ± 0,735 mm). El cemento a base de hidróxido de calcio (Sealer 26) fue más efectivo frente a S. mutans (13,010 ± 2,006 mm) que ante E. faecalis (6,165 ± 0,978 mm) y C. albicans (5,640 ± 0,280 mm). Como conclusión, el cemento a base de óxido de zinc y eugenol (Endofill) mostró el mejor efecto antimicrobiano contra las tres cepas, seguido de los cementos a base de resina (Vioseal) y finalmente hidróxido de calcio (Sealer 26).

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Section: Discussionunclassified

Efecto Antimicrobiano de Tres Cementos Selladores Endodónticos frente a Streptococcus mutans, Enterococcus faecalis y Candida albicans

Chambilla-Torres

Sánchez-Tito

2021

Int. J. Odontostomat.

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“…The EndoVac irrigation/aspiration system associated with chemomechanical debridement was the most effective therapeutic protocol for reducing intra-canal levels of C. albicans [47] . AH 26 exhibited strong activity against this pathogen with the minimum inhibitory concentration of 12.5 mg.ml [48] . In order to eliminate C. albicans, the literature mentions that if it comes in direct contact with calcium hydroxide, it can be completely inhibited after 48 hours.…”

Section: Treatmentmentioning

confidence: 99%

Candida albicans, from endodontic point of view

Perez¹,

Treviño-Tijerina²,

Leal-Camarillo³

et al. 2021

Int. J. Appl. Dent. Sci.

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Introduction: Candida albicans is a ubiquitous commensal organism that commonly colonizes the oral mucosa. In fact, up to 80% of the general population are carriers. Objective: To analyze the literature about C. albicans, its epidemiology, diagnosis, clinical manifestations, antimicrobial resistance and treatment in relation to endodontics. Methodology: Using the keywords Candida albicans in conjunction with epidemiology, diagnosis, clinical manifestations, antimicrobial resistance and treatment, the main public databases were searched, with emphasis on the last 5 years. It was evaluated with the PRISMA and AMSTAR-2 guidelines. Results: C. albicans is the fungus most frequently isolated in root canal infections, it binds to the dentin to form biofilms within the dentin tubules. C. albicans can be detected by different diagnostic methods, the most used is cultivation. This microorganism is increasingly found in the oral cavity, it is responsible for endodontic failure, its biofilms are inherently resistant to antifungal drugs, the host's immune system, environmental stresses and biomechanical treatment. The most favourable method to eliminate is using Qmi X irritant and Endo Vac as a suction system, together with chemo mechanical debridement. Conclusions: C. albicans is a pathogen which has been presenting itself more frequently in the oral cavity, in the endodontic area, it is the fungus that is most frequently found in the root canals, either due to primary or secondary infection.

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“…[17][18][19][20] The agar diffusion test has been widely used for this purpose. 3,6,15,16,21,22 As an in vitro method, it requires the investigated material to diffuse into the agar, and the inhibitory effects are a combination of diffusion potential and antimicrobial activity. 23 The root canal filling materials used in deciduous dentition are divided into several groups according to their active ingredients (Table 1).…”

Section: Aimmentioning

confidence: 99%

Root canal filling materials in primary teeth - review

Shindova¹

2021

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Inadequate treatment of endodontic infections in primary teeth results in a loss of а deciduous tooth or abnormality in the development of hard dental tissues of the permanent successor. The main goal is to maintain the integrity and health of the primary tooth until their physiological exfoliation. The success of the endodontic treatment depends on the antimicrobial activity of the root canal filling material that contributes to the elimination or reduction of the microbial infection of the root canal system. The aim of this article is to systematically review the contemporary scientific literature concerning the root canal filling materials used in primary teeth. A critical evaluation of the antimicrobial activity, as well as the advantages and disadvantages of the investigated materials, has been made. Knowledge of the composition and characteristics of the available obturating materials is a useful advantage to dentists to address the functional problems associated with endodontic infections in very young patients. Future studies should also seek and compare the long-term effects of the use of traditional and alternative intracanal materials.

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In vitro antimicrobial effect of different root canal sealers against oral pathogens

Cited by 14 publications

References 37 publications

Efecto Antimicrobiano de Tres Cementos Selladores Endodónticos frente a Streptococcus mutans, Enterococcus faecalis y Candida albicans

Efecto Antimicrobiano de Tres Cementos Selladores Endodónticos frente a Streptococcus mutans, Enterococcus faecalis y Candida albicans

Candida albicans, from endodontic point of view

Root canal filling materials in primary teeth - review

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