In vitro antimicrobial effects of grape seed extract on peri-implantitis microflora in craniofacial implants

Shrestha, Binit; Theerathavaj, M.L. Srithavaj; Thaweboon, Sroisiri; Thaweboon, Boonyanit

doi:10.1016/s2221-1691(12)60236-6

Cited by 28 publications

(22 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some studies that made use of P reported several MIC values against S. aureus such as 242 mg/mL (Nuamsetti, Dechayuenyong, & Tantipaibulvut, 2012), 2 mg/mL (Al-Zoreky, 2009) 15.6 mg/mL (Naziri, Rajaian, & Firouzi, 2012), and 50 mg/mL (Gullon, Pintado, Pérez-Alvarez, & Viuda-Martos, 2016). There are also some studies in which MIC values were reported as 0.625 mg/mL (Shrestha, Theerathavaj, Thaweboon, & Thaweboon, 2012) The differences in MIC values are thought to be caused by the characteristics of the materials used in extraction, extraction procedures and solvents, or differences in the resistance levels of the strains used (McCarrell et al, 2008). As a result, it has been found that all the extracts used in this study had significant antimicrobial activity on…”

Section: Discussionmentioning

confidence: 70%

“…Some studies that made use of P reported several MIC values against S. aureus such as 242 mg/mL (Nuamsetti, Dechayuenyong, & Tantipaibulvut, ), 2 mg/mL (Al‐Zoreky, ) 15.6 mg/mL (Naziri, Rajaian, & Firouzi, ), and 50 mg/mL (Gullon, Pintado, Pérez‐Álvarez, & Viuda‐Martos, ). There are also some studies in which MIC values were reported as 0.625 mg/mL (Shrestha, Theerathavaj, Thaweboon, & Thaweboon, ) and 1.156‐ ≤ 150 μL (Al‐Nimer, Rasheed, & Saadaldin, ) for GS extracts against S. aureus . Similarly, various MIC values such as 0.2–0.5 mg/mL (Hannan, Saleem, Chaudhary, & Barkaat, ) and 1,125 μg/mL (Alam, Yasmin, Nessa, & Ahsan, ) were reported for NS extract.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Investigation of different interactions between Staphylococcus aureus phages and pomegranate peel, grape seed, and black cumin extracts

Tayyarcan

Soykut

Yilmaz

et al. 2019

Journal of Food Safety

View full text Add to dashboard Cite

Today, antibiotic resistance is one of the most crucial problems so that researchers have begun to search for alternatives to antibiotics. Among these alternatives, phage therapy and phytotherapy became prominent. The present study aims to put forward a different approach by combining these two methods. For this purpose, Staphylococcus aureus phages were isolated from commercial mixtures. After that, extraction of phenolic compounds from pomegranate peels (Ps), grape seeds (GSs), and black cumin (NS) was carried out and antimicrobial activities were determined. Phage‐phenolic interactions were investigated by examining the effect of phenolic extracts on phage plaque sizes and then on phage titer and bacteria count. As a result, it was found that only the NS extract had a positive effect on phage activity and increased the size of phage plaques. However, no synergistic effect was observed in experiments performed in liquid media. It was also found that P and GS extracts inhibited phage activity. Practical Applications The present study was focused on effects of extracts obtained from pomegranate peel, grape seed, and black cumin on Staphylococcus aureus phage activity. It is known that antibiotic resistance constitutes a major obstacle to the pathogen elimination. In this study, phage therapy and phytotherapy, which are prominent methods in pathogen elimination, have been combined and the effect of phenolic compounds isolated from natural sources on phage activity and bacteria count have been examined. Given the results of the current study, it has been demonstrated that the combined use of phages and antimicrobial compounds could be an important alternative to combating pathogens. It is thought that this combined method should be taken into consideration both in the practice of phage therapy on humans and animals, and in applications in the food industry.

show abstract

Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

Investigation of different interactions between Staphylococcus aureus phages and pomegranate peel, grape seed, and black cumin extracts

Tayyarcan

Soykut

Yilmaz

et al. 2019

Journal of Food Safety

View full text Add to dashboard Cite

show abstract

“…According to Binith Shrestha and Srithavaj et al, the structure-activity correlation assays showed that the hydroxyl group of the phenolic compound was found to be effective against E.coli and the benzene ring was effective against S. aureus. 8 According to Al-Habeb A and Al-Saleh E et al the antibacterial effect of grape seed extract against MRSA is due to disruption of bacterial cell wall membrane in scanning and transmission electron microscopy which could be accounted to the presence of potent polyphenolics in grape seed extract. 9 Though the study produced moderate zones of inhibition which was comparable to that of the stated references; it can further be performed with better methodologies to improve the results and to increase the effectiveness of grape seed extract against virulent strains…”

Section: Discussionmentioning

confidence: 99%

A study on antibacterial effect of grape seed extracts in common clinical and drug resistant isolates

Kandasamy¹,

Nasimuddin²,

Malayan³

et al. 2016

Int J Clin Trials

View full text Add to dashboard Cite

Background: Grape seeds are proposed to have antimicrobial activity, antioxidant effect and various other benefits to mankind. A study was done to assess the antibacterial effect of grape seed extract against common clinical isolates and drug resistant pathogenic strains.Methods: Grape seed extract prepared was investigated for its antibacterial effect against 65 bacterial isolates obtained from clinical specimens by agar well diffusion assay and the results were compared with routinely used antibiotics namely, Gentamicin for the common clinical isolates, Vancomycin for MRSA strains and Amikacin for ESBL organisms respectively.Results: Grape seed extract produced moderate zone of inhibition ranging between 11-15 mm among the 35 test common clinical isolates namely Staphylococcus aureus, Escherichia coli, Klebsiella sp and Pseudomonas aeruginosa. E.coli showed the highest susceptibility with zone ranging from 12-14 mm with increasing concentration of the extract starting from2 mg/ml to the highest being 20 mg/ml. Among the 30 drug resistant pathogenic strains like MRSA and ESBL producing organisms, the grape seed extract was found to be effective against 3 out of the 10 of MRSA and 2 out of the 10 of ESBL-E.coli at the highest concentration of 20 mg/ml. However, ESBL producing Klebsiella species were found to be resistant even to the highest concentration of the extract. Conclusions: The results provide evidence that the grape seed extract could be a potential antibacterial agent and this effect can further be made evident with improved methodologies.

show abstract

“…Treating peri-implantitis involves antioxidant supplemention [4]. Sheresta et al stated that grape seed extract has positive effect on treating peri-implantitis [23]. For bone healing and bone formation, it was reported that caffeic acid phenethyl ester which can be found in propolis have significantly improved bone healing in rat models [24].…”

Section: Oral-maxillofacial Surgerymentioning

confidence: 99%

Antioxidants In Dentistry: Review Of Literature

Aksakalli¹

2013

Dentistry

View full text Add to dashboard Cite

An antioxidant is molecule that can inhibit oxidations and free radicals' harmful activities. There are many types of antioxidant products in the market and they can be produced from several sources including minerals, vitamins or food and herbal supplements. In developed countries, consumption of antioxidants has become widespread. As in every medical field, the usage of antioxidants is becoming more frequent. Antioxidants can help adjunct treating the progress of oral problems such as periodontitis or gingivitis. The properties of antioxidants have been studied to understand their mechanisms, to clarify their activities and the increasing evidences are raising hopes about antioxidants for human health.

show abstract

In vitro antimicrobial effects of grape seed extract on peri-implantitis microflora in craniofacial implants

Cited by 28 publications

References 10 publications

Investigation of different interactions between Staphylococcus aureus phages and pomegranate peel, grape seed, and black cumin extracts

Investigation of different interactions between Staphylococcus aureus phages and pomegranate peel, grape seed, and black cumin extracts

A study on antibacterial effect of grape seed extracts in common clinical and drug resistant isolates

Antioxidants In Dentistry: Review Of Literature

Contact Info

Product

Resources

About