In vitro antimicrobial mechanism of diacerein and potential to reverse MRSE resistance to β-lactams
Chunyan Fu,
Yi Xu,
Liping Mao
et al.
Abstract:Staphylococcus epidermidisis the most common pathogens causing ocular infection. With the increase of drug resistance rate, it poses a new challenge to anti-infection treatment. In this study, we analyzed the drug resistance ofS. epidermidisisolated from the eye in the past 5 years to guide empirical antibiotics treatment. Then, the MIC and MBC of diacerein against MRSE were detected, and continuous induced resistance experiments confirmed that MRSE not easily induce resistance to diacerein. In addition, it wa… Show more
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