In vitro antioxidant actions of sulfur-containing amino acids

Kim, Ji-Han; Jang, Hohyoun; Cho, Won Yong; Yeon, Su‐Jung; Lee, Chi H.

doi:10.1016/j.arabjc.2017.12.036

Cited by 90 publications

(40 citation statements)

References 32 publications

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“…The reduction of Fe 3+ to generate residual Fe 2+ measures the degree ferric reducing antioxidant power (FRAP) (Kim, Jang, Cho, Yeon, & Lee, 2020; Nwachukwu & Aluko, 2019). FRAP is often used to evaluate the ability of an antioxidant to donate an electron or hydrogen, and some research have indicated that there is a direct correlation between antioxidant activities and reducing power of peptide (Tang et al., 2012).…”

Section: Resultsmentioning

confidence: 99%

Amino acid composition and antioxidant properties of the enzymatic hydrolysate of calabash nutmeg ( Monodora myristica ) and its membrane ultrafiltration peptide fractions

et al. 2020

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The aim of this work was to determine amino acid composition and in vitro antioxidant activities of Monodora myristica protein hydrolysate and its membrane ultrafiltration peptide fractions. The Alcalase hydrolysate was fractionated using ultrafiltration membranes to produce peptide sizes of <1, 1-3, 3-5, and 5-10 kDa. The results showed that sequential fractionation resulted in higher glycine and glutamic acid and glutamine contents. Analysis of in vitro antioxidant properties showed that fractionation of the M. myristica hydrolysate led to significant (p < .05) improvements in 2,2-diphenyl-1-picrylhydrazyl radical scavenging, metal chelation activity, ferric reducing antioxidant power (FRAP), and hydroxyl (OH) radical scavenging activity. Linoleic acid oxidation was significantly (p < .05) attenuated by the peptide fractions. We conclude that peptide antioxidant activities were significantly (p < .05) improved by membrane fractionation, especially the 3-5 kDa fraction. How to cite this article: Akinyede AI, Fagbemi TN, Osundahunsi OF, Aluko RE. Amino acid composition and antioxidant properties of the enzymatic hydrolysate of calabash nutmeg (Monodora myristica) and its membrane ultrafiltration peptide fractions.

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Section: Resultsmentioning

confidence: 99%

Amino acid composition and antioxidant properties of the enzymatic hydrolysate of calabash nutmeg ( Monodora myristica ) and its membrane ultrafiltration peptide fractions

et al. 2020

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“…In vitro taurine showed chelating activity against copper and zinc, but not iron. The ability was weaker than other sulphur-containing amino acids [57]. On the other hand, according to Harraki et al [58], the structure of taurine molecule is unlikely to indicate the possibility of zinc chelation.…”

Section: Discussionmentioning

confidence: 80%

The Influence of Taurine Supplementation on Serum and Tissular Fe, Zn and Cu Levels in Normal and Diet-Induced Insulin-Resistant Rats

Król

Okulicz

Kupsz

2020

Biol Trace Elem Res

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Taurine (Tau) is a β-sulphonated amino acid postulated to improve glucose homeostasis in insulin resistance and diabetes. Changes in carbohydrate metabolism are accompanied by oxidative stress, which may disturb the mineral balance. Therefore, the aim of this study was to assess the effect of Tau supplementation on the levels of trace elements in rats fed either a standard (AIN-93M, 4% fat) diet or a modified high-fat diet (30% fat). For 8 weeks, male Wistar rats were fed these diets supplemented with 3% Tau. Taurine supplementation normalized increased serum insulin concentration and insulin resistance index; however, it did not improve serum CRP concentration in high-fat diet fed rats. The high-fat diet supplemented with Tau decreased the renal and splenic Zn levels, but the tissular Fe content did not change. The effect of Tau supplementation on the mineral balance to some extent depended on the fat content in the rats' diet. The high-fat diet supplemented with Tau decreased the rats' splenic Zn levels but increased their femur levels. In the group fed the standard diet, Tau reduced the rats' femur Zn level, whereas their splenic Zn level was comparable. Tau supplementation decreased the renal Cu level and serum ceruloplasmin concentration in the rats fed the standard diet, but this effect was not observed in the rats fed the high-fat diet. In conclusion, supplementary taurine failed to ameliorate disturbances in mineral homeostasis caused by high-fat diet feeding and led to tissular redistribution of Zn and Cu in the rat.

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“…Such discrepancies could be due to some differences of the other nutrient contents as reported [ 20 ]. For example, proteins have been reported to display radical scavenging activity as determined by the DPPH assay due to the antioxidant activity of sulfur-containing amino acids such as methionines and cysteines [ 21 ]. Therefore, methanolic extracts of DCM, PCM, and LCM were also prepared by removing proteins using organic extraction with chloroform to assess the DPPH radical scavenging activity.…”

Section: Resultsmentioning

confidence: 99%

Antioxidant and Nutritional Properties of Domestic and Commercial Coconut Milk Preparations

Karunasiri

Gunawardane

Senanayake

et al. 2020

International Journal of Food Science

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The aqueous extract of scraped coconut kernel is known as coconut milk. Coconut milk preparations are also commercially available in the form of desiccated powders or liquids. While these various coconut milk preparations are heavily used in cooking in the Asian countries as a major source of dietary fat, limited studies have been conducted on their chemical and nutritional composition. In this study, we have determined the chemical composition and nutritional effects of both domestic preparations of coconut milk and the commercially available counterparts. The results indicate that the phenolic compounds of all coconut milk preparations provide protection against oxidative damage on lipids and inhibit oxidative damage of both proteins and DNA. The lipid profiles are not significantly affected by the consumption of the three coconut milk preparations despite their different fat contents.

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In vitro antioxidant actions of sulfur-containing amino acids

Cited by 90 publications

References 32 publications

Amino acid composition and antioxidant properties of the enzymatic hydrolysate of calabash nutmeg ( Monodora myristica ) and its membrane ultrafiltration peptide fractions

Amino acid composition and antioxidant properties of the enzymatic hydrolysate of calabash nutmeg ( Monodora myristica ) and its membrane ultrafiltration peptide fractions

The Influence of Taurine Supplementation on Serum and Tissular Fe, Zn and Cu Levels in Normal and Diet-Induced Insulin-Resistant Rats

Antioxidant and Nutritional Properties of Domestic and Commercial Coconut Milk Preparations

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