Article InfoThe present study has been carried out to investigate the presence of DPPH radical scavenging activity of ethanolic crude leaf extracts of Capparis sepiaria, Euphorbia heterophylla and Tamilnadia uliginosa. The leaves were collected, shade dried, powdered and extracted with ethanol. The crude form of the leaf extracts were taken for radical scavenging activity against free radical using a 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical activity. The results showed that in all the extracts, the DPPH activity was found to be concentration dependent. At the concentration of 75 μl/ml ethanol extract of Tamilnadia uliginosa yielded the highest radical scavenging activity of 77.6±4.5%. Ethanol leaf extract of Tamilnadia uliginosa was found to possess strong antioxidant activity assessed by means of DPPH activity.