In vitro antioxidant and anti-inflammatory activities of Melipona beecheii honey protein fractions

Ruíz-Ruíz, Jorge Carlos; Acereto-Escoffié, Pablo; Campos, Maira Rubí Segura

doi:10.1007/s11694-018-9881-6

Cited by 2 publications

(4 citation statements)

References 17 publications

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“…On day 1, the inflammatory phase emerged, likely due to honey's content of phenolic compounds (26,27), glycopeptides (28), and low molecular weight proteins (29). These components stimulate monocytes and macrophages, enhancing the release of cytokines, chemokines, and enzymes that break down the extracellular matrix.…”

Section: Despitementioning

confidence: 99%

In Vivo Wound-Healing and Anti-Inflammatory Activities of Honey Produced by Melipona beecheii Bees

Ramírez Miranda,

Acevedo-Fernandez,

Negrete-Leon

et al. 2024

Jundishapur J Nat Pharm Prod

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Background: Honey produced by the Melipona beecheii bees has been highly prized in Mexico since pre-Hispanic times for its therapeutic properties, particularly in wound healing. Objectives: The aim of this study was to assess the in vivo wound-healing and anti-inflammatory effects of M. beecheii honey using an animal model. Methods: Honey samples were collected from the state of Yucatan, Mexico. Male albino mice were utilized to test the wound-healing and anti-inflammatory properties of the honey, with pirfenidone (KitosCell®) and indomethacin (1 and 30 mg/mL) serving as positive controls, respectively. Results: From day one, enhancements in wound healing, granulation tissue formation, and continuous contraction of the wound edges were observed. In terms of anti-inflammatory activity, the honey dose was capable of reducing edema comparably to the control group receiving 1 mg/mL of indomethacin. However, differences were noted when compared to the 30 mg/mL indomethacin control group in three of the groups. Conclusions: It can be concluded that M. beecheii honey exhibits wound-healing and anti-inflammatory effects comparable to those of the positive controls used in this study. Therefore, it offers a viable alternative for the topical treatment of wounds.

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Section: Despitementioning

confidence: 99%

In Vivo Wound-Healing and Anti-Inflammatory Activities of Honey Produced by Melipona beecheii Bees

Ramírez Miranda,

Acevedo-Fernandez,

Negrete-Leon

et al. 2024

Jundishapur J Nat Pharm Prod

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“…57 Additionally, proteins from Melipona beecheii honey were found to be partially related to the antioxidant and anti-inflammatory activity of honey by in vitro assays. 57…”

Section: Antioxidant Activitymentioning

confidence: 99%

“…Besides phenolics, proteins, carotenoids, ascorbic acid and Maillard reaction products also have antioxidant activities 34,68 . The antioxidant and anti‐inflammatory activities of proteins from beech honey were studied by in vitro assay 57 . The low‐molecular‐weight fraction, consisting of proteins with molecular weights of 7.04, 14.07 and 24.16 kDa, had high antioxidant activities with low IC 50 (concentration providing 50% of radical scavenging) values for free radical scavenging activity, chelating effect and reducing power 57 .…”

Section: Functional Characteristicsmentioning

confidence: 99%

“…The antioxidant and anti‐inflammatory activities of proteins from beech honey were studied by in vitro assay 57 . The low‐molecular‐weight fraction, consisting of proteins with molecular weights of 7.04, 14.07 and 24.16 kDa, had high antioxidant activities with low IC 50 (concentration providing 50% of radical scavenging) values for free radical scavenging activity, chelating effect and reducing power 57 . Additionally, proteins from Melipona beecheii honey were found to be partially related to the antioxidant and anti‐inflammatory activity of honey by in vitro assays 57 …”

Section: Functional Characteristicsmentioning

confidence: 99%

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Composition, functional properties and safety of honey: a review

Wang

Lin

et al. 2023

J Sci Food Agric

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Honey has been used not only as a food source but also for medicinal purposes. Recent studies have indicated that honey exhibits antioxidant, hepatoprotective, hypolipidemic, hypoglycemic and anti‐obesity properties, as well as anticancer, anti‐atherosclerotic, hypotensive, neuroprotective and immunomodulatory activities. These health benefits of honey could be attributed to its wide range of nutritional components, including polysaccharides and polyphenols, which have been proven to possess various beneficial properties. It is notable that the composition of honey can also be affected by nectar, season, geography and storage condition. Moreover, the safety of honey requires caution to avoid any potential safety incidents. Therefore, this review aims to provide recent research regarding the chemical composition, biological activities and safety of honey, which might be attributed to comprehensive utilization of honey. © 2023 Society of Chemical Industry.

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In vitro antioxidant and anti-inflammatory activities of Melipona beecheii honey protein fractions

Cited by 2 publications

References 17 publications

In Vivo Wound-Healing and Anti-Inflammatory Activities of Honey Produced by Melipona beecheii Bees

In Vivo Wound-Healing and Anti-Inflammatory Activities of Honey Produced by Melipona beecheii Bees

Composition, functional properties and safety of honey: a review

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