In vitro Antisalmonellal and Antioxidant Activities of Extracts and Fractions of Curcuma longa L. Rhizomes (Zingiberaceae)

Kodjio, Norbert; Atsafack, Serge Secco; Fodouop, Siméon P. C.; Kuiaté, Jules-Roger; Gatsing, Donatien

doi:10.9734/ijbcrr/2016/25106

Cited by 6 publications

(2 citation statements)

References 24 publications

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“…These results are in agreement with those of Kushwah, et al [34], Prakash, et al [23] who had obtained similar antioxidant activities with methanol extracts of T. grandis. However, these studies are in agreement with those of Kodjio, et al [35], Djoueudam, et al [36 ] and Sokoudjou, et al [2] who showed the mixed anti-salmonellal and antioxidant activity of some medicinal plants.…”

Section: In Vitro Antioxidant Activitiessupporting

confidence: 92%

In vitro Antisalmonellal and Antioxidant Activities of Leaves Extracts of Tectona grandis L. F. (Verbenaceae)

Kamsu

Tagne

Fodouop

et al. 2019

EJMP

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Aim: Study aimed to evaluate the in vitro antisalmonellal and antioxidant properties of Tectona grandis, a medicinal plant commonly used in traditional Cameroonian medicine for the treatment of typhoid fever. Study Design: In vitro Antimicrobial and antioxidant analyses of plant extract using established protocols. Place and Duration of Study: Plant materiel collection at Loum (Moungo Division, Littoral region of Cameroon), identification at the National Herbarium of Cameroon, extraction of plant and all analyses at the Research Unit of Microbiology and Antimicrobial Substances, Department of Biochemistry, University of Dschang-Cameroon, between August 2018 and April 2019. Methodology: In vitro antisalmonellal activity of Tectona grandis extracts was evaluated by the liquid microdilution method as well as their antioxidant activity using by standard methods of H2O2 trapping, FRAP, DPPH radical trapping and OH radical trapping. Quantification test of total phenols and flavonoids and phytochemical screening of extract were also done. Results: The results showed that most of the Tectona grandis extracts had minimal inhibitory concentrations (MICs) ranging from 64 to 1024 μg/mL. Ethanolic extract, 70% ethanol extract and aqueous decoction are the most effective compared to aqueous extracts with activities between 64 and 128 μg/mL on the bacteria tested. Antioxidant tests showed that all extracts except macerated and aqueous infused extracts exhibited high DPPH trapping activities. The antioxidant activities of the extracts are proportionally linked in most cases to their flavonoid and total phenol contents at a concentration of 200 µg/mL. Aqueous decoction showed better H2O2 trapping activity at concentrations less than or equal to 25 µg/mL. Conclusion: These results show that the ethanolic extract and decocted aqueous of Tectona grandis leaves can be used as an alternative to treat salmonellosis.

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Section: In Vitro Antioxidant Activitiessupporting

confidence: 92%

In vitro Antisalmonellal and Antioxidant Activities of Leaves Extracts of Tectona grandis L. F. (Verbenaceae)

Kamsu

Tagne

Fodouop

et al. 2019

EJMP

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“…Specifically, it is rich in pharmacological activities, including antibacterial [7], anti-tumor [8], anti-oxidation [9], anti-allergy [10] and antiinflammatory [11]. At present, many studies in China, Brazil and Japan have focused on the bacteriostasis of Zingiberaceae with respect to food hygiene [12], human health [13], animal and plant disease prevention [14,15]. Through research report shows that many Zingiberaceae plants on Gram-positive bacteria and Gram-negative bacteria have obvious growth inhibition.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Anti-Bacterial and Anti-Fungal Activities of Extracts from Different Parts of 7 Zingiberaceae Plants

Wu¹,

Li²,

Li³

et al. 2023

Journal of Renewable Materials

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This study aimed to explore the anti-bacterial and anti-fungal activities of extracts from different parts of plants in the Zingiberaceae family. The inhibitory rate, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) of leaf and stem, and root and rhizome extracts from Alpinia katsumadai Hayata, Alpinia oxyphylla Miq × Alpinia henryi K. Schumann, Alpinia oblongifolia Hayata, Alpinia nigra (Gaertn.) Burtt, Amomum villosum Lour, Alpinia zerumbet (Pers.) Burtt. et Smith and Alpinia oxyphylla Miq were determined using the fungus cake method and double dilution method. The seven Zingiberaceae plants exhibited characteristic antibacterial activities against pathogenic bacteria and fungi. At a 1.5 mg mL −1 , A. zerumbet root and rhizome extracts exhibited strong inhibitory activity against S. aureus and E. coli, with 83.23% and 79.62%, respectively. In addition, A. zerumbet leaf and stem extracts had an inhibitory rate of 90.85% against P. aeruginosa. At the same concentration, the leaf and stem, root and rhizome extracts of A. katsumadai had the best antibacterial effect against F. oxysporum, with inhibition rates of 84.46% and 84.73%, respectively. Moreover, A. katsumadai and A. zerumbet leaf and stem extracts had the most significant antibacterial effect against S. aureus, with a MIC of 0.063 mg mL −1 . Thus, both A. katsumadai and A. zerumbet extracts had significant antibacterial activity. In addition, by comparing the inhibitory effect of extracts from different parts, it was found that the inhibitory rate and average inhibitory rate of extracts from leaf and stem were higher than those from root and rhizome. The chemical constituents of A. katsumadai and A. zerumbet, determined by the high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), revealed that citric acid (CA), alpinetin, and pinocembrin (PNCB) were the functional constituents yielding the antibacterial activity. Overall, A. katsumadai and A. zerumbet have the potential to be developed as new plant fungicides and bactericides. KEYWORDSZingiberaceae; pathogens; in vitro antibacterial activity; minimum inhibitory concentration (MIC); minimum bactericidal concentration (MBC); high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)

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Hepatoprotective and antioxidant effects of Commelina diffusa Burm extracts on gentamicin-induced liver damage in rats

SL¹,

Serges²,

Laure³

et al. 2020

JPBS

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Commelina diffusa is a plant rich in antioxidant compounds, used in traditional medicine to treat many diseases. This study aimed to evaluate the hepatoprotective and antioxidant activities of aqueous and methanolic extracts of Commelina diffusa. Total phenolic and flavonoids content of extracts were determined. Hepatotoxicity was induced in rats by administration of gentamicin (80 mg/kg, i.p.) once daily for 10 days. Simultaneously, extracts were given at doses of 100 and 200 mg/kg, p.o. At the end of treatment, body weight of rats was measured; blood and liver tissues were collected for biochemical and histopathological analysis. The results showed that aqueous and methanolic extracts of C. diffusa contain significant amounts of total phenols and flavonoids. These extracts significantly decreased (p<0.05 to p<0.001) liver weight, activity of transaminases and alkaline phosphatase and the levels of malondialdehyde, bilirubin, LDL cholesterol, triglycerides and total cholesterol. In contrast they significantly increased (p<0.05 to p< 0.01) the body weight of rats, the levels of HDL cholesterol, total protein, glutathione and the activity of catalase and superoxide dismutase. Histopathological examination revealed that extracts protected liver tissues against cell infiltration and centrolobular necrosis induced by gentamicin. These results suggest that Commelina diffusa could protect against hepatotoxic effects of gentamicin.

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In vitro Antisalmonellal and Antioxidant Activities of Extracts and Fractions of Curcuma longa L. Rhizomes (Zingiberaceae)

Cited by 6 publications

References 24 publications

In vitro Antisalmonellal and Antioxidant Activities of Leaves Extracts of Tectona grandis L. F. (Verbenaceae)

In vitro Antisalmonellal and Antioxidant Activities of Leaves Extracts of Tectona grandis L. F. (Verbenaceae)

In Vitro Anti-Bacterial and Anti-Fungal Activities of Extracts from Different Parts of 7 Zingiberaceae Plants

Hepatoprotective and antioxidant effects of Commelina diffusa Burm extracts on gentamicin-induced liver damage in rats

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