In vitro assessment of 3 dentifrices containing fluoride in preventing demineralization of overdenture abutments and root surfaces

Goettsche, Zachary S.; Ettinger, Ronald L.; Wefel, James S.; Hogan, Mary M.; Harless, J.D.; Qian, Fang

doi:10.1016/j.prosdent.2014.01.031

Cited by 6 publications

(6 citation statements)

References 13 publications

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“…Rough denture surfaces accumulate more plaque and oral proteins, promoting microbial colonization and proliferation. Adhesion of C. albicans is promoted by rough surfaces and has been shown to play an important role in the pathogenesis of DS [36,37]. In the present study, incorporating MPC at its highest weight percentage of 4.5% did not influence the roughness measurements compared with the control group with 0% MPC.…”

Section: Discussioncontrasting

confidence: 49%

“…In addition, it was previously shown that fluctuations in environmental pH can influence microbial growth and survival [36]. Lactic acid produced by cariogenic bacteria can also cause tooth demineralization, especially in over-denture abutments and root surfaces [37]. For that reason, the effect of adding MPC into HIPA resin on solution pH was investigated.…”

Section: Discussionmentioning

confidence: 99%

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Antibiofilm and Protein-Repellent Polymethylmethacrylate Denture Base Acrylic Resin for Treatment of Denture Stomatitis

et al. 2021

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Candida albicans (C. albicans) biofilm is a common etiological factor in denture stomatitis. The purpose of this study was to investigate the effects of incorporating 2-methacryloyloxyethyl phosphorylcholine (MPC) as a protein repellent into a new high-impact denture acrylic (HIPA) resin on the surface roughness, solution pH, and C. albicans biofilm adhesion to the denture base. The new acrylic denture resin base was formulated by mixing MPC into HIPA resin at mass fractions of 1.5%, 3%, and 4.5%. Surface roughness was measured using a Mitutoyo surface roughness tester. C. albicans biofilm growth and viability were assessed via colony forming unit counts. The pH of the biofilm growth medium was measured using a digital pH meter. Adding MPC to the HIPA resin at percentages of 1.5% and 3% increased the roughness values significantly (P < 0.05), while adding 4.5% MPC resulted in no difference in roughness values to that of the control group (P > 0.05). All experimental groups demonstrated neutral pH values (pH @ 7) and were not significantly different from each other (P > 0.05). Incorporating 2-methacryloyloxyethyl phosphorylcholine at 4.5% resulted in a significant (@1 log) colony-forming unit reduction compared with the control group with 0% MPC (P < 0.05). A fungal-retarding denture acrylic resin was developed through the incorporation of MPC for its protein-repelling properties. This newly developed denture acrylic material has the potential to prevent oral microbial infections, such as denture stomatitis.

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Section: Discussioncontrasting

confidence: 49%

Section: Discussionmentioning

confidence: 99%

Antibiofilm and Protein-Repellent Polymethylmethacrylate Denture Base Acrylic Resin for Treatment of Denture Stomatitis

et al. 2021

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“…However, the pHc procedure, by simulating de-remineralisation cycles, is generally accepted and employed in dental research due to the technically simple method and reproducible results [51]. The demineralisation cycles correspond to the period in which teeth are exposed to bacterial acids, while the remineralisation cycles correspond to the remineralising action of saliva between the acidic exposures [52]. Several variations in the pHc procedure have been applied that influence the resulting lesions, such as immersion/exposure times, temperature, solution agitation, pH, and duration (days).…”

Section: Discussionmentioning

confidence: 99%

Chemical, Microstructural and Morphological Characterisation of Dentine Caries Simulation by pH-Cycling

et al. 2021

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In vitro simulation of natural caries is of great importance in dental research for the development of more effective clinical treatments. The pH-cycling (pHc) procedure consists of a dynamic caries process with alternating de-remineralisation periods. The current research aims to evaluate the effects of the pHc procedure on mineral dentine properties in comparison with sound dentine and natural residual caries. For this purpose, dentine slices from human third molars were submitted to cycling periods of 14 and 28 days. The chemical composition, morphological and microstructural properties of the dentine samples were examined by infrared and Raman spectroscopies, X-ray diffraction, and scanning electron microscopy techniques. In addition, the depth of the demineralisation front was evaluated by Masson’s trichrome (MT) staining. The results showed that the pHc procedure led to notable changes in the mineral composition and the crystalline characteristics with respect to sound dentine and some extent to natural caries. The MT results revealed that pHc 28 yields a deeper lesion than pHc 14, simulating potential progression of natural caries. The results of this study provide a better understanding of the mechanisms of demineralisation that could occur in an in vivo environment and provide a standardised substrate similar to natural residual caries.

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“…For varnishes containing NaF plus TCP, the remineralizing effect for enamel (and dentin) varied between significantly inferior [31], as good as [30,32] and significantly superior [33] when compared with NaF (without TCP). Regarding the anti-caries effect of dentifrices containing 5000 ppm F − plus TCP, only surrogate outcomes as photomicrographs [34] have been used in vitro. However, in situ, a significantly higher mineral gain could be observed for dentifrices containing 5000 ppm F − plus TCP when compared with dentifrices containing solely 5000 ppm F − [35].…”

Section: Discussionmentioning

confidence: 99%

Influence of highly concentrated fluoride dentifrices on remineralization characteristics of enamel in vitro

et al. 2018

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In vitro assessment of 3 dentifrices containing fluoride in preventing demineralization of overdenture abutments and root surfaces

Cited by 6 publications

References 13 publications

Antibiofilm and Protein-Repellent Polymethylmethacrylate Denture Base Acrylic Resin for Treatment of Denture Stomatitis

Antibiofilm and Protein-Repellent Polymethylmethacrylate Denture Base Acrylic Resin for Treatment of Denture Stomatitis

Chemical, Microstructural and Morphological Characterisation of Dentine Caries Simulation by pH-Cycling

Influence of highly concentrated fluoride dentifrices on remineralization characteristics of enamel in vitro

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