In vitro binding of bile acids by soy protein, pinto beans, black beans and wheat gluten

An In‐vitro Investigation of Selected Biological Activities of Hydrolysed Flaxseed (Linum usitatissimum L.) Proteins

“…Only a few studies have reported bile acid binding of proteins and their hydrolysates in-vitro, including soy protein, wheat gluten [39] lupin protein [9] and rapeseed protein. In a previous study, lupin protein isolate (1 mg/ ml, protein content 91.44%) was able to bind 55.8% SCDC, 54.4% SC, 40.9% STC, 63.9% SGC and 58.4% SDC.…”

In vitro binding of bile salts by lentil flours, lentil protein concentrates and lentil protein hydrolysates

“…Other studies have reported in vitro binding of bile acids and salts by lupin proteins and their hydrolysates (Yoshie-Stark & Wäsche, 2004), rapeseed proteins and their hydrolysates (Yoshie-Stark, Wada, & Wäsche, 2008), soy proteins (Choi, Adachi, & Utsumi, 2002;Higaki et al, 2006;Kahlon & Woodruff, 2002), wheat gluten (Kahlon & Woodruff, 2002) and enzymatic digests of buckwheat proteins (Ma & Xiong, 2009). In vitro bile acid-binding capacity was also demonstrated for some fruits and legumes (Kahlon, Chapman, & Smith, 2007;Kahlon & Shao, 2004;Kahlon & Smith, 2007a,b;Kahlon, Smith, & Shao, 2005;Kahlon & Woodruff, 2002). However, there are no reports in the literature on the bile acid binding properties of pulses such as lentils.…”

Nutritional Weight Loss Therapy with Cooked Bean Powders Regulates Serum Lipids and Biochemical Analytes in Overweight and Obese Dogs

“…In contrast, dry bean fiber has been shown to alter blood lipids by preventing micelle formation and preventing absorption of cholesterol and fatty acids making these compounds available for fermentation in the large intestine, and increasing the rate of removal of LDL [60]. In vitro studies have suggested that dry beans have a higher capacity for binding to bile acids than do soy proteins or wheat gluten [61,62] and rat studies have shown higher bile acid synthesis and excretion with whole bean diets [63,64]. Human studies have further demonstrated the interruption of the enterohepatic circulation of bile acids and increased excretion of acidic fecal sterols after prolonged bean consumption [65].…”