In vitro bioactivity of glass–ceramics of the CaMgSi2O6–CaSiO3–Ca5(PO4)3F–Na2SiO3 system with TiO2 or ZnO additives

Salman, S.M.; Salama, S.N.; Darwish, H.; Abo-Mosallam, H.A.

doi:10.1016/j.ceramint.2008.04.025

Cited by 28 publications

(15 citation statements)

References 15 publications

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“…9). These results confirm the formation of an apatite layer on the surface of WPC paste disc after immersion in SBF solution 30 . The X-ray diffraction (XRD) of the samples after immersion in SBF is shown in Fig.…”

Section: Bioactivity In Vitrosupporting

confidence: 77%

Untitled

Torkittikul¹,

Chaipanich²

2009

ScienceAsia

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Biomaterials containing calcium silicate have been widely used in dental and bone repaired applications. This study investigated mechanical and in vitro biological properties of ordinary and white Portland cement both of which are composed mainly of calcium silicates. The time of setting was determined using a Vicat needle. Compressive strength was measured at the age of 1, 3, and 7 days. The 1 day set Portland cement pastes were soaked in a simulated body fluid to investigate the ability of the material to form a bond with living bone tissue. X-ray diffraction traces of samples following immersion in simulated body fluid demonstrated that both cement pastes form a hydroxyapatite layer within 7 days but white Portland cement shows a noticeably higher amount of apatite crystal than that of ordinary Portland cement. Scanning electron micrographs reveal a clear presence of hydroxyapatite on the surface of white, but not in ordinary Portland cement. In addition, white Portland cement can achieve a compressive strength of 30 MPa within 24 h after curing in distilled water at human temperature.

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Section: Bioactivity In Vitrosupporting

confidence: 77%

Untitled

Torkittikul¹,

Chaipanich²

2009

ScienceAsia

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“…This decrease can be understood by taking into account the initial fast release of zinc ions to SBF solution, which changes the solution acidity [2,23]. It was also found that the enhanced release of zinc ions causes simultaneous decrease of both pH of the solution and amount of Si ions leached out from the sample as ZnO has been known as an amphoteric oxide that improves chemical durability by reducing the dissolution rate of glass-ceramic samples by decreasing the number of non-bridging oxygens [3,11].…”

Section: Aas Analysismentioning

confidence: 99%

“…The SBF solution was buffered to a pH value of 7.4 with Tris (hydroxymethyl) aminomethane (NH 2 C(CH 2 OH) 3 ) and 1M hydrochloric acid (HCL) at 37°C. All the glass-ceramic samples were soaked in above mentioned SBF under static condition at 37°C for different time periods 1, 7, 21, 24 and 30 days.…”

Section: In Vitro Bioactivity Analysismentioning

confidence: 99%

“…An increase in concentration of ZnO in glass and glass-ceramic system causes decline in apatite forming ability. The amount of ZnO to a base system, which may lower the bioactivity level, was defined as 5 % by S. M. Salman et al [3] while M. Kamitakahara et al [11] reported more than 0.7 % ZnO and A.K. Srivastava and R. Pyare 2012 findings suggested that more than 1 % ZnO content to base system lowered the bioactivity level.…”

Section: Introductionmentioning

confidence: 99%

“…The most useful property of glass-ceramics, which shows the ability of the material to form a direct bond to a living bone, is bioactivity [2]. Bioactivity is a spontaneous communication of materials in biological environment, which results in strong adhesion between tissue-implant interface [3].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

In vitro evaluation of bioactivity of SiO2-CaO-P2O5-Na2O-CaF2-ZnO glass-ceramics

Riaz

Zia

Saleemi

et al. 2014

Materials Science-Poland

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Zinc is an essential trace element that stimulates bone formation but it is also known as an inhibitor of apatite crystal growth. In this work addition of ZnO to SiO 2 -CaO-P 2 O 5 -Na 2 O-CaF 2 glass-ceramic system was made by conventional meltquenching technique. DSC curves showed that the addition of ZnO moved the endothermic and exothermic peaks to lower temperatures. X-ray diffraction analysis did not reveal any additional phase caused by ZnO addition and showed the presence of wollastonite and hydroxyapatite crystalline phases only in all the glass-ceramic samples. As bio-implant apatite forming ability is an essential condition, the surface reactivity of the prepared glass-ceramic specimens was studied in vitro in Kokubo's simulated body fluid (SBF) [1] with ion concentration nearly equal to human blood plasma for 30 days at 37°C under static condition. Atomic absorption spectroscopy (AAS) was used to study the changes in element concentrations in soaking solutions and XRD, FT-IR and SEM were used to elucidate surface properties of prepared glass-ceramics, which confirmed the formation of HCAp on the surface of all glass-ceramics. It was found that the addition of ZnO had a positive effect on bioactivity of glassceramics and made it a potential candidate for restoration of damaged bones.

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