In vitro biosynthesis of human chorionic follicle stimulating hormone.

Synthesis of Proteins in the Placenta

“…Like the FSH of pituitary origin, but unlike hCG, hCFSH stimulates cell division in the ovary. Experiments using explants of early placentas incubated with 3H-proline and Ij|C-glutamate provided evidence of the independent synthesis of hCFSH and hCG [77]. For several decades reports have suggested that a substance with adrenocorticotropic activity can be isolated from human placentas, but the question has remained [78] as to whether the placental extracts might be contaminated by ACTH secreted by the maternal pituitary.…”