In vitro characterization of the digestive stress response and immunomodulatory properties of microorganisms isolated from smear-ripened cheese

Adouard, Nadège; Foligné, Benoît; Dewulf, Joëlle; Bouix, Marielle; Picque, Daniel; Bonnarme, Pascal

doi:10.1016/j.ijfoodmicro.2014.12.011

Cited by 13 publications

(4 citation statements)

References 39 publications

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“…Given the clear association of UC pathology with neutrophil accumulation, the ability of probiotics to regulate the recruitment, function, or apoptosis of neutrophils has the potential to greatly influence the disease course (Table 4). Beneficial effects of probiotics in limiting neutrophilassociated damage may stem from their ability to modulate the production of neutrophil chemotaxins and activators such as IL-17 and IL-8 (311)(312)(313)(314)(315)(316).…”

Section: Protective Mechanisms Of Probiotics Against Ulcerative Colitismentioning

confidence: 99%

Gleaning Insights from Fecal Microbiota Transplantation and Probiotic Studies for the Rational Design of Combination Microbial Therapies

et al. 2017

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SUMMARY Beneficial microorganisms hold promise for the treatment of numerous gastrointestinal diseases. The transfer of whole microbiota via fecal transplantation has already been shown to ameliorate the severity of diseases such as Clostridium difficile infection, inflammatory bowel disease, and others. However, the exact mechanisms of fecal microbiota transplant efficacy and the particular strains conferring this benefit are still unclear. Rationally designed combinations of microbial preparations may enable more efficient and effective treatment approaches tailored to particular diseases. Here we use an infectious disease, C. difficile infection, and an inflammatory disorder, the inflammatory bowel disease ulcerative colitis, as examples to facilitate the discussion of how microbial therapy might be rationally designed for specific gastrointestinal diseases. Fecal microbiota transplantation has already shown some efficacy in the treatment of both these disorders; detailed comparisons of studies evaluating commensal and probiotic organisms in the context of these disparate gastrointestinal diseases may shed light on potential protective mechanisms and elucidate how future microbial therapies can be tailored to particular diseases.

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Section: Protective Mechanisms Of Probiotics Against Ulcerative Colitismentioning

confidence: 99%

Gleaning Insights from Fecal Microbiota Transplantation and Probiotic Studies for the Rational Design of Combination Microbial Therapies

et al. 2017

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“…Such can occur without any detectable shift in taxa within the resident microbiota and are clearly strain specific. 14 These effects are not linked to either species or food type, even if some species have consistently demonstrated promising properties. 15,16 For example, specific Propionibacterium freundenreichii strains (found in Swiss-type cheeses such as Emmental) can display anti-inflammatory properties, 17 and certain Hafnia alvei strains (found in Camembert or Italian stretched curd cheeses) appear to help with obesity-related disorders.…”

Section: Food and Function Reviewmentioning

confidence: 99%

Underlying evidence for the health benefits of fermented foods in humans

et al. 2022

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“…Strains of Serratia marcescens (Db10, JUb9, SM25, SM38, and SM45) were kindly provided by Dr. Elizabeth Pradel (Institut Pasteur de Lille, Lille, France) [56]. Some cheese-derived Hafnia alvei strains (Gb01, E215, 920 and Grignon) have been described elsewhere [57]. Lastly, a few bacterial strains (nine Bifidobacterium species, four Cutibacterium acnes, two Enterobacter, two Hafnia alvei, and five Klebsiella) were sourced from historical clinical gut or fecal samples of human origin, from food, or as re-isolates from commercial probiotic products (Bb12 and Morinaga) held in a collection at the Faculty of Pharmacy of Lille (FPL collection), University of Lille, France.…”

Section: Bacterial Strains Collections and Culture Conditionsmentioning

confidence: 99%

Assessment of Pb(II), Cd(II), and Al(III) Removal Capacity of Bacteria from Food and Gut Ecological Niches: Insights into Biodiversity to Limit Intestinal Biodisponibility of Toxic Metals

et al. 2021

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Toxic metals (such as lead, cadmium, and, to a lesser extent, aluminum) are detrimental to health when ingested in food or water or when inhaled. By interacting with heavy metals, gut and food-derived microbes can actively and/or passively modulate (by adsorption and/or sequestration) the bioavailability of these toxins inside the gut. This “intestinal bioremediation” involves the selection of safe microbes specifically able to immobilize metals. We used inductively coupled plasma mass spectrometry to investigate the in vitro ability of 225 bacteria to remove the potentially harmful trace elements lead, cadmium, and aluminum. Interspecies and intraspecies comparisons were performed among the Firmicutes (mostly lactic acid bacteria, including Lactobacillus spp., with some Lactococcus, Pediococcus, and Carnobacterium representatives), Actinobacteria, and Proteobacteria. The removal of a mixture of lead and cadmium was also investigated. Although the objective of the study was not to elucidate the mechanisms of heavy metal removal for each strain and each metal, we nevertheless identified promising candidate bacteria as probiotics for the intestinal bioremediation of Pb(II) and Cd(II).

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In vitro characterization of the digestive stress response and immunomodulatory properties of microorganisms isolated from smear-ripened cheese

Cited by 13 publications

References 39 publications

Gleaning Insights from Fecal Microbiota Transplantation and Probiotic Studies for the Rational Design of Combination Microbial Therapies

Gleaning Insights from Fecal Microbiota Transplantation and Probiotic Studies for the Rational Design of Combination Microbial Therapies

Underlying evidence for the health benefits of fermented foods in humans

Assessment of Pb(II), Cd(II), and Al(III) Removal Capacity of Bacteria from Food and Gut Ecological Niches: Insights into Biodiversity to Limit Intestinal Biodisponibility of Toxic Metals

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