In Vitro Comparison of Second- and Third-generation Dual-source CT for Coronary Stent Visualization at Different Tube Potentials

Gassenmaier, Tobias; Petri, Nils; Allmendinger, Thomas; Flohr, Thomas; Weng, Andreas Max; Kunz, Andreas Steven; Petritsch, Bernhard; Voelker, Wolfram; Bley, Thorsten Alexander

doi:10.1016/j.acra.2016.03.011

Cited by 7 publications

(4 citation statements)

References 19 publications

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“…This better imaging quality on third-generation CT may improve lesion detectability, although we did not assess this in the current study. Previously, image quality on third-generation CT was reported to be better than that on second-generation CT with respect to contrast-enhanced imaging [33,36,37] and stent lumen visibility [32]. Regarding contrast-enhanced CT, the availability of high tubecurrent on third-generation CT provides noise reduction, thus resulting in improvement of the CT image quality, particularly at the low tube-voltage used on contrast-enhanced CT [38].…”

Section: Discussionmentioning

confidence: 99%

“…In particular, third-generation CT includes new detectors with integrated electronics with contacting technology to reduce the distance between the photodiode and the analog-to-digital converter electronics; this can reduce noise and artifact [30,31]. The image quality of third-generation CT has been reported to show improvements in angiography [28], coronary stent visualization [32], and truncal cancer imaging [33]. However, improvement in the image quality of pediatric unenhanced head CT has been little evaluated.…”

Section: Introductionmentioning

confidence: 99%

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Improved Imaging Quality of the Pediatric Brain on Third-Generation CT

Niwa¹,

Okazaki²,

Hara³

et al. 2020

BJSTR

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Background: Third-generation computed tomography (CT) has advances in detector efficiency, and newer iterative reconstruction (IR) algorithms Objective: To retrospectively compare pediatric brain imaging quality between second-and third-generation CT.Methods: Image quality was compared between second-and third-generation CT in 51 pairs of age-matched children (age range, 0-5 years) with no abnormal findings. CT images were reconstructed using filtered back-projection (FBP) and IR. The contrastto-noise ratio (CNR) and signal-to-noise ratio (SNR) were calculated at the lentiform nucleus (LN) and white matter (WM). Imaging contrast at the gray-WM interface was rated by two readers. Results:The CNR and SNR of the LN and WM were significantly higher on thirdgeneration CT than on second-generation CT (mean CNR, 2.51 vs 2.12, p < 0.001; mean SNR for LN, 15.13 vs 12.71, p < 0.001; mean SNR for WM, 12.27 vs 11.12, p = 0.012) when FBP was used. With FBP, both readers rated visually assessed grey-white matter contrast as better on third-generation CT than on second-generation CT (p ≤ 0.002). With IR, the CNR and SNR were significantly higher than with FBP on both generation CT scanners (p < 0.001). The LN CNR was significantly higher on third-generation CT than on second-generation CT (mean, 16.79 vs 15.13, p < 0.001). With IR, visual assessments on third-generation CT were generally better than on second-generation CT. Conclusion:Imaging quality of the pediatric brain was better on third-generation CT than on second-generation CT. IR may be effective on CT scanners of both generations.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Improved Imaging Quality of the Pediatric Brain on Third-Generation CT

Niwa¹,

Okazaki²,

Hara³

et al. 2020

BJSTR

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“…When choosing lower tube voltages, stent lumen visibility is slightly reduced. 23 We have measured the image noise; however, we think that the coronary flow of the heart model contributes to the artefacts, thus rendering this parameter non-valid.…”

Section: Discussionmentioning

confidence: 99%

Influence of cardiac motion on stent lumen visualization in third generation dual-source CT employing a pulsatile heart model

Petri¹,

Gassenmaier²,

Allmendinger³

et al. 2017

The British Journal of Radiology

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Objective: To detect an in-stent restenosis, an invasive coronary angiography is commonly performed. Owing to the risk associated with this procedure, a non-invasive method to detect or exclude an in-stent restenosis is desirable. The purpose of this study was to evaluate the influence of cardiac motion on stent lumen visibility in a third-generation dualsource CT scanner (SOMATOM Force; Siemens Healthcare, Forchheim, Germany), employing a pulsatile heart model (CoroSim®; Mecora, Aachen, Germany). Methods: 13 coronary stents with a diameter of 3.0 mm were implanted in plastic tubes filled with a contrast medium and then fixed onto the pulsatile phantom heart model. The scans were performed while the heart model mimicked the heartbeat. Coronary stents were scanned in an orientation parallel to the scanner z-axis. The evaluation of the stents was performed by employing a medium sharp convolution kernel optimized for vascular imaging. Results: The mean visible stent lumen was reduced from 65.6 6 5.7% for the stents at rest to 60.8 6 4.4% for the stents in motion (p-value: ,0.001). Conclusion: While the difference in lumen visibility between stents in motion and at rest was significant, the use of this third-generation dual-source CT scanner enabled a high stent lumen visibility under the influence of cardiac motion. Whether this translates into a clinical setting has to be evaluated in further patient studies. Advances in knowledge: The employed modern CT scanner enables a high stent lumen visibility even under the influence of cardiac motion, which is important to detect or exclude an in-stent restenosis.

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“…Although imaging of stents in lower extremity PAD remains a compelling indication for PCD-CT, this topic is still hugely underrepresented in the literature, and systematic analyses that tap into the full potential of the new detector technology are warranted. Although stent imaging has traditionally been a favored application to test the performance of new detector generations, 4,9,[24][25][26][27] most studies comparing the potential of PCD-CT to EID-CTs rely on phantom studies. In clinical studies, where repeated scanning is prohibited by ethical and radiation protection constraints, comparative studies usually use matched cohorts.…”

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confidence: 99%

Photon-Counting Detector CT for Femoral Stent Imaging in an Extracorporeally Perfused Human Cadaveric Model

Hartung,

Gruschwitz,

Huflage

et al. 2023

Invest Radiol

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Background and Aims This study aims to compare the performance of first-generation dual-source photon-counting detector computed tomography (PCD-CT) to third-generation dual-source energy-integrating detector (EID-CT) regarding stent imaging in the femoral arterial runoff. Methods Continuous extracorporeal perfusion was established in 1 human cadaver using an inguinal and infragenicular access and peristaltic pump. Seven peripheral stents were implanted into both superior femoral arteries by means of percutaneous angioplasty. Radiation dose-equivalent CT angiographies (high-/medium-/low-dose: 10/5/3 mGy) with constant tube voltage of 120 kVp, matching iterative reconstruction algorithm levels, and convolution kernels were used both with PCD-CT and EID-CT. In-stent lumen visibility, luminal and in-stent attenuation as well as contrast-to-noise ratio (CNR) were assessed via region of interest and diameter measurements. Results were compared using analyses of variance and regression analyses. Results Maximum in-stent lumen visibility achieved with PCD-CT was 94.48% ± 2.62%. The PCD-CT protocol with the lowest lumen visibility (BV40: 78.93% ± 4.67%) performed equal to the EID-CT protocol with the best lumen visibility (BV59: 79.49% ± 2.64%, P > 0.999). Photon-counting detector CT yielded superior CNR compared with EID-CT regardless of kernel and dose level (P < 0.001). Maximum CNR was 48.8 ± 17.4 in PCD-CT versus 31.28 ± 5.7 in EID-CT (both BV40, high-dose). The theoretical dose reduction potential of PCD-CT over EID-CT was established at 88% (BV40), 83% (BV48/49), and 73% (BV59/60), respectively. In-stent attenuation was not significantly different from luminal attenuation outside stents in any protocol. Conclusions With superior lumen visibility and CNR, PCD-CT allowed for noticeable dose reduction over EID-CT while maintaining image quality in a continuously perfused human cadaveric model.

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In Vitro Comparison of Second- and Third-generation Dual-source CT for Coronary Stent Visualization at Different Tube Potentials

Cited by 7 publications

References 19 publications

Improved Imaging Quality of the Pediatric Brain on Third-Generation CT

Improved Imaging Quality of the Pediatric Brain on Third-Generation CT

Influence of cardiac motion on stent lumen visualization in third generation dual-source CT employing a pulsatile heart model

Photon-Counting Detector CT for Femoral Stent Imaging in an Extracorporeally Perfused Human Cadaveric Model

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