In-vitro corrosion and bioactivity behavior of tailored calcium phosphate-containing zinc oxide coating prepared by plasma electrolytic oxidation

Bordbar‐Khiabani, Aidin; Ebrahimi, Sema; Yarmand, Benyamin

doi:10.1016/j.corsci.2020.108781

Cited by 44 publications

(18 citation statements)

References 78 publications

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“…This review does not cover these topics and they can be found elsewhere [ 51 ]. In recent years, plasma electrolytic oxidation (PEO) method has been studied for improving metallic implants’ corrosion resistance [ 52 ]. In this method, the micro-porous oxide layers are grown on a metallic substrate during oxidation process [ 52 ].…”

Section: Conventional Drug-eluting Implantsmentioning

confidence: 99%

“…In recent years, plasma electrolytic oxidation (PEO) method has been studied for improving metallic implants’ corrosion resistance [ 52 ]. In this method, the micro-porous oxide layers are grown on a metallic substrate during oxidation process [ 52 ]. The porous oxide layer can act as a polymer-free drug delivery platform [ 53 ].…”

Section: Conventional Drug-eluting Implantsmentioning

confidence: 99%

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Recent Advancements in Metallic Drug-Eluting Implants

et al. 2023

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Over the past decade, metallic drug-eluting implants have gained significance in orthopedic and dental applications for controlled drug release, specifically for preventing infection associated with implants. Recent studies showed that metallic implants loaded with drugs were substituted for conventional bare metal implants to achieve sustained and controlled drug release, resulting in a desired local therapeutic concentration. A number of secondary features can be provided by the incorporated active molecules, including the promotion of osteoconduction and angiogenesis, the inhibition of bacterial invasion, and the modulation of host body reaction. This paper reviews recent trends in the development of the metallic drug-eluting implants with various drug delivery systems in the past three years. There are various types of drug-eluting implants that have been developed to meet this purpose, depending on the drug or agents that have been loaded on them. These include anti-inflammatory drugs, antibiotics agents, growth factors, and anti-resorptive drugs.

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Section: Conventional Drug-eluting Implantsmentioning

confidence: 99%

Section: Conventional Drug-eluting Implantsmentioning

confidence: 99%

Recent Advancements in Metallic Drug-Eluting Implants

et al. 2023

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“…Therefore, when a composite is exposed to biodegradation tests, bioactivity will also be exhibited in SBF, and degradation will be affected, simulating better in vivo conditions. A composite's in vivo examination is not only limited to the release of drugs but also extended to its bioactivity [149,150].…”

Section: In Vitro and In Vivo Drug Release Studiesmentioning

confidence: 99%

Sol-gel: Uncomplicated, routine and affordable synthesis procedure for utilization of composites in drug delivery: Review

Azadani

Sabbagh²,

Salehi

et al. 2021

jcc

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“…As an effective, rapid, and low-cost method, surface modification technologies, such as the sol-gel method, electrochemical deposition, plasma spraying, micro-arc oxidation (MAO), and hydrothermal treatment (HT), have been established to optimize the corrosion property and biocompatibility of alloys [19][20][21][22][23][24][25][26]. Among these technologies, MAO is a simple, effective, and rapid method for improving the corrosion properties of alloys [27,28].…”

Section: Introductionmentioning

confidence: 99%

Corrosion and Biocompatibility of Pure Zn with a Micro-Arc-Oxidized Layer Coated with Calcium Phosphate

et al. 2021

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Recent studies have indicated a great demand to optimize the biocompatibility properties of pure Zn as an implant material. For this purpose, CaZn2(PO4)2·2H2O (CaZnP) was prepared using hydrothermal treatment (HT) combined with micro-arc oxidation (MAO) on pure Zn substrate to generate biodegradable implants. The polarization test and electrochemical impedance spectroscopy indicated that the MAO1−HT coating could modulate the corrosion behavior of MAO1 by filling the crevice between the coating and the substrate. Immersion test evaluation revealed that the osteogenic properties of MAO1−HT coating were better than that of pure Zn substrate, as evidenced by the molar ratio of Ca and P, which increased after soaking in simulated body fluid (SBF) for up to 10 days. In addition, L-929 cells cultured in the 100%, 50%, and 25% extracts of MAO1−HT coated samples exhibited excellent cytocompatibility. Meanwhile, cell adhesion was promoted on the surface with high roughness generated during MAO and HT processes. In summary, the calcified coatings improved biocompatibility and adjusted the degradation rates of pure Zn, broadening the application of Zn alloys.

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In-vitro corrosion and bioactivity behavior of tailored calcium phosphate-containing zinc oxide coating prepared by plasma electrolytic oxidation

Cited by 44 publications

References 78 publications

Recent Advancements in Metallic Drug-Eluting Implants

Recent Advancements in Metallic Drug-Eluting Implants

Sol-gel: Uncomplicated, routine and affordable synthesis procedure for utilization of composites in drug delivery: Review

Corrosion and Biocompatibility of Pure Zn with a Micro-Arc-Oxidized Layer Coated with Calcium Phosphate

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