In vitro cultivation of Toxocara cati adult worms for production of eggs and evaluation of oviposition

Zibaei, Mohammad; Sadjjadi, Seyed Mahmoud; Sarkari, Bahador; Oryan, Ahmad; Uga, Shoji

doi:10.2478/s11687-009-0005-z

Cited by 3 publications

(2 citation statements)

References 17 publications

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“…The diagnosis is most established by confirmatory serological testing using an ELISA (enzyme linked-immunosorbent assay) that detecting IgG antibodies against TES ( Toxocara excretory-secretory) antigens (TES-ELISA). ES proteins from second stage T. canis or T. cati larvae maintained in vitro form the substrate for ELISA [ 71 , 72 ]. The sensitivity and specifity have been estimated to be approximately 78.0% and 92.0% for T. canis and 97.0% and 96.7% for T. cati , respectively [ 73 - 75 ].…”

Section: Laboratory Diagnosismentioning

confidence: 99%

Helminth Infections and Cardiovascular Diseases: Toxocara Species is Contributing to the Disease

Zibaei

2016

CCR

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Toxocariasis is the clinical term used to describe human infection with either the dog ascarid Toxocara canis or the feline ascarid Toxocara cati. As with other helminths zoonoses, the infective larvae of these Toxocara species cannot mature into adults in the human host. Instead, the worms wander through organs and tissues, mainly the liver, lungs, myocardium, kidney and central nervous system, in a vain attempt to find that, which they need to mature into adults. The migration of these immature nematode larvae causes local and systemic inflammation, resulting in the “larva migrans” syndrome. The clinical manifestations of toxocariasis are divided into visceral larva migrans, ocular larva migrans and neurotoxocariasis. Subclinical infection is often referred to as covert toxocariasis. One of the primary causes of death all around the world is cardiovascular disease that accounted for up to 30 percent of all-cause mortality. Cardiovascular disease and more precisely atherosclerotic cardiovascular disease, is predicted to remain the single leading cause of death (23.3 million deaths by 2030). A-quarter of people presenting the disease does not show any of the known cardiovascular risk factors. Therefore, there is considerable interest in looking for novel components affecting cardiovascular health, especially for those that could improve global cardiovascular risk prediction. This review endeavours to summarize the clinical aspects, new diagnostic and therapeutic perspectives of toxocaral disease with cardiovascular manifestations.

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Section: Laboratory Diagnosismentioning

confidence: 99%

Helminth Infections and Cardiovascular Diseases: Toxocara Species is Contributing to the Disease

Zibaei

2016

CCR

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“…Despite the poor hygiene and inappropriate anthelmintic treatments in dogs in rural settings, environmental contamination with Toxocara eggs is common in outdoor parks of urban and suburban settings [4,8,9]. Human beings as paratenic hosts become infected by ingestion of embryonated eggs in soil, from contaminated vegetables and fruits or consuming raw or undercooked meat and viscera of infected paratenic hosts including chicken, calves and lambs [7,[10][11][12].…”

Section: Editorialmentioning

confidence: 99%