In vitro degradation and mechanical integrity of Mg–Zn–Ca alloy coated with Ca-deficient hydroxyapatite by the pulse electrodeposition process☆

Porous magnesium-based scaffolds for tissue engineering

“…Although hydroxyapatite has exceptional biocompatibility, bioactivity properties, and similar chemical and structural nature as bone, it suffers from high brittleness and low strength which limits its application in load bearing conditions [55]. Therefore, utilizing biodegradable magnesium scaffolds with appropriate mechanics, coated with hydroxyapatite to enhance corrosion resistance, and to enhance bone forming ability can be a promising scaffold for bone tissue engineering in load bearing applications [56]. Different techniques such as sputtering process, electrophoretic deposition, sol-gel process, and biomimetic deposits can be used to coat metallic surfaces by hydroxyapatite.…”

“…Different techniques such as sputtering process, electrophoretic deposition, sol-gel process, and biomimetic deposits can be used to coat metallic surfaces by hydroxyapatite. However, due to the poor heat resistance of magnesium, none of these techniques can be used efficiently for hydroxyapatite coating of magnesium scaffolds since a high temperature treatment will be required to densify the coating [56].…”

“…Therefore, one of the promising options to surface modify magnesium scaffolds is using electrochemical deposition which includes low deposition temperature and is capable of creating uniform coatings with controlled thickness and chemical composition [56][57][58].…”

“…Incorporating Zn element in contents of less than 3% can improve the corrosion resistance [60] and the mechanical properties of magnesium scaffolds [56,61].…”

Hydroxyapatite coating on AZ91 magnesium alloy via sol-gel method

“…Günümüz biyomalzeme uygulamalarının gözde konusu kemiğin kimyasal yapısı ve mekanik özellikleriyle doğrudan benzeyen Magnezyum alaşımlarıdır [1]- [5]. Özellikle yoğunluğu ve elastik modülü, 1.74-2 g/cm 3 ve 41-45 GPa olup kemiğinkine çok yakındır (1.8-2.1 g/cm 3 , 3-20 GPa) [6].…”