In vitro Efficacy of Herbal Extracts against Eimeria tenella

Zaman, M. A.; Iqbal, Zafar; Abbas, Rao Zahid; Ehtisham-ul-Haque, Syed

doi:10.17957/ijab/14.0008

Cited by 16 publications

(4 citation statements)

References 10 publications

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“…However, no positive result was observed. Arfan Zaman et al (2015) in vitro evaluated the effect of Curcuma longa leaves, Artemisia absinthium seeds, and Saussurea lappa roots on the sporulation of Eimeria tenella: the extract of C. longa had the highest inhibitory effect. Fatemi et al (2015) compared the effect of different Artemisia annua extracts on the sporulation rate of E. acervulina, E. necatrix, and E. tenella oocysts.…”

Section: Discussionmentioning

confidence: 99%

Influence of temperature on sporulation of Eimeria arloingi and Eimeria perforans oocysts

Boyko

Shendryk

Rudyk

et al. 2021

Regul. Mech. Biosyst.

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Eimeriosis of farm animals is one of the most widespread parasitic diseases in the world. In the conditions of the steppe zone of Ukraine Eimeria perforans is more common in rabbits and E. arloingi in sheep and goats. Study of factors which influence the development of these protists on the soil surface is one of the major challenges for veterinarians working for large livestock companies and fighting against eimeriosis. Environmental temperature is able to change the speed of sporulation of oocysts Eimeria. Five values of temperature (15, 20, 25, 30, and 35 °C) were used in a laboratory experiment in vitro. At 15 °C, the process of sporulation of E. arloingi and E. perforans in 100% of cases ended on the eighth day. With increase in temperature to 35 °C, the duration of sporulation decreased to three days. When the temperature was 30 °C the completion of sporulation was observed in more than 50% of the oocysts of E. arloingi on the second day, and for E. perforans on the third day. High-speed sporulation at elevated temperatures under conditions of global warming can result in the increasing spread of eimeriosis among wild and domestic animals.

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Section: Discussionmentioning

confidence: 99%

Influence of temperature on sporulation of Eimeria arloingi and Eimeria perforans oocysts

Boyko

Shendryk

Rudyk

et al. 2021

Regul. Mech. Biosyst.

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“…The parasite then invades and undergoes intracellular reproduction in the intestinal epithelium. Chickens infected with coccidiosis have systemic symptoms such as anorexia, bloody diarrhea, weight loss, and death in chicks that are severely infected (Zaman et al, 2015). Of chickens infected with Eimeria spp., 20 % are clinical and 5 % are sub-clinical.…”

Section: Introductionmentioning

confidence: 99%

The effects of infectious dosages on endogenous phage and the excretion of Eimeria tenella oocysts of infected chicken

Dung,

Nguyen,

Nguyen

et al. 2024

VIS

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This study was conducted to evaluate the effects of four dosages of oocyst inoculation (1×102, 1×103, 1×104, and 1×105 oocysts/chick) on oocyst patterns in feces, lesion score, and the endogenous phase of Eimeria tenella in the tissue of infected chickens. Oocysts in feces were collected daily from 4 to 10 day-post-infection (dpi). Chickens were killed at 0, 3, 5, and 10 dpi to evaluate the lesion score and the endogenous phage in the tissue by hematoxylin and eosin staining. The results showed that chickens in the highest dosage group discharged oocysts the earliest (5 dpi), while oocysts were detected in the other 3 groups 1 day later (6 dpi). The results of the histopathological examination showed that the time to detect the development stages of E. tenella in the tissue was similar among the experimental groups. Specifically, the asexual stages (1st and 2nd schizonts) were detected at 3 dpi, and immature oocysts were found in the cecum tissue at 5 dpi in all experimental groups. Overall, the results indicated that the oocyst dosages do not affect the replication of E. tenella in intestinal epithelial cells but may influence the excretion of oocysts from the intestinal tissue.

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“…Phytochemicals from different types of botanical elements have been explored as sustainable alternatives to management of coccidiosis (Hady and Zaki, 2012). A wide variety of herbal extracts have been shown to have anti-parasitic activity, while others can enhance the immune system and growth performance, thereby helping the host to overcome coccidiosis infection (Zaman et al, 2015;Debbou-Iouknane et al, 2019). Among the plant extracts, bromelain obtained from pineapples (Ananas comosus) has been shown in a previous In vitro study, to have high activity against Eimeria spp.…”

Section: Introductionmentioning

confidence: 99%

Assessment of anticoccidial efficacy of chitosan nanoencapsulated bromelain against coccidia in naturally infected goats in Kenya

Daiba¹,

Ngotho²,

Kagira³

et al. 2023

Afr. J. Biotechnol.

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The current study assessed the anticoccidial efficacy of chitosan nanoencapsulated bromelain (CNB) against coccidiosis in goats. Bromelain was extracted from the pineapple peels using standard methods while oral solution of CNB was prepared using standard manufacturing methods. The in vivo study was done on fifteen healthy male goats naturally infected with coccidia. The goats were divided into three groups consisting of three treatment groups (90 and 270 mg/Kg CNB, Diclazuril, 5 mg/Kg). The drugs were administered orally for 3 days. Fecal Oocyst Counts (FOC) determined using the modified McMaster technique. The goats were observed for clinical signs on daily basis while body weight was recorded weekly. The level of packed cell volume (PCV), aspartate aminotransferases (AST), alanine aminotransferases (ALT), urea, and creatinine were assessed weekly. At the end of the study, goats were euthanized and gross pathology and histopathology conducted. The results showed that at day 28 post-treatment there was a significantly reduction of FOC of 98.42 and 82.30% for Diclazuril and 270 mg/Kg treatment groups, respectively. The reduction of FOC percentage was significantly higher (p ≤ 0.01) in Diclazuril group than that in 270 mg/Kg. During the monitoring period, there was no mortality or clinical signs observed in the goats. The PCV, AST, ALT, creatinine and urea were in normal ranges for goats. There were no pathological lesions on the goat organs. In conclusion, CNB had high anticoccidial efficacy and was safe for use in goats. Strategies to improve the efficacy of this potential drug should be further investigated.

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In vitro Efficacy of Herbal Extracts against Eimeria tenella

Cited by 16 publications

References 10 publications

Influence of temperature on sporulation of Eimeria arloingi and Eimeria perforans oocysts

Influence of temperature on sporulation of Eimeria arloingi and Eimeria perforans oocysts

The effects of infectious dosages on endogenous phage and the excretion of Eimeria tenella oocysts of infected chicken

Assessment of anticoccidial efficacy of chitosan nanoencapsulated bromelain against coccidia in naturally infected goats in Kenya

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