In vitro evaluation of Pt-coated electrospun nanofibers for endovascular coil embolization

Kim, Min Woo; An, Seongpil; Seok, Hyunjun; Jung, Hyunchul; Park, Dong Hyuk; Yarin, Alexander L.; Yoon, Sam S.

doi:10.1016/j.actbio.2019.10.015

Cited by 2 publications

(2 citation statements)

References 25 publications

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“…Figure shows the process used for fabricating copper (Cu) microfibers via the combined electrospinning and electroplating techniques. ,− First, an electrospinning solution comprising 8 wt % polyacrylonitrile (PAN, (C 3 H 3 N) n , M w = 150 kDa, Sigma-Aldrich) and N , N -dimethyl formamide (DMF, 99.8%, Sigma-Aldrich) was prepared by dissolving PAN in DMF and then magnetically stirring the mixed solution at room temperature (20 °C) for 24 h. Thereafter, the fully dissolved 8 wt % PAN solution was electrospun using a syringe pump (Legato 100, KDS) and a DC power supply (EL20P2, Glassman High Voltage Inc.). The electrospinning parameters are listed in Table .…”

Section: Methodsmentioning

confidence: 99%

Transparent Metallized Microfibers as Recyclable Electrostatic Air Filters with Ionization

Kim

Seok

et al. 2020

ACS Appl. Mater. Interfaces

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Air-quality control remains a major environmental concern as polluted air is a threat to public safety and health in major industrialized cities. To filter pollutants, fibrous filters employing electrostatic attraction have been widely used. However, such air filters suffer from some major disadvantages, including low recyclability and a significant pressure drop owing to clogging and a high packing density. Herein, we developed ionization-assisted electrostatic air filters consisting of nonwoven nanofibers. Ionization of particulate matter (PM) using air ionization enhanced the electrostatic attraction, thereby promoting efficient filtration. Metallization of the fibers facilitated strong electrical attraction and the consequent capture of PM of various sizes. The low packing density of the metallized fibers also facilitated efficient filtration of the PM, even at low driving pressures, which in turn reduced the energy consumption of the air-filtration device.

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Section: Methodsmentioning

confidence: 99%

Transparent Metallized Microfibers as Recyclable Electrostatic Air Filters with Ionization

Kim

Seok

et al. 2020

ACS Appl. Mater. Interfaces

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“…Thus, this material always comprises spinnerets to transfer electrostatic energy to the working fluid. Whole-metal spinnerets are commonly connected to a power supply through an alligator clip [ 44 , 45 , 46 ]. However, the metal spinneret and clip could similarly disperse electrostatic energy to the environment through the atmosphere, especially in humid weather.…”

Section: Introductionmentioning

confidence: 99%

Energy-Saving Electrospinning with a Concentric Teflon-Core Rod Spinneret to Create Medicated Nanofibers

et al. 2020

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Although electrospun nanofibers are expanding their potential commercial applications in various fields, the issue of energy savings, which are important for cost reduction and technological feasibility, has received little attention to date. In this study, a concentric spinneret with a solid Teflon-core rod was developed to implement an energy-saving electrospinning process. Ketoprofen and polyvinylpyrrolidone (PVP) were used as a model of a poorly water-soluble drug and a filament-forming matrix, respectively, to obtain nanofibrous films via traditional tube-based electrospinning and the proposed solid rod-based electrospinning method. The functional performances of the films were compared through in vitro drug dissolution experiments and ex vivo sublingual drug permeation tests. Results demonstrated that both types of nanofibrous films do not significantly differ in terms of medical applications. However, the new process required only 53.9% of the energy consumed by the traditional method. This achievement was realized by the introduction of several engineering improvements based on applied surface modifications, such as a less energy dispersive air-epoxy resin surface of the spinneret, a free liquid guiding without backward capillary force of the Teflon-core rod, and a smaller fluid–Teflon adhesive force. Other non-conductive materials could be explored to develop new spinnerets offering good engineering control and energy savings to obtain low-cost electrospun polymeric nanofibers.

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In vitro evaluation of Pt-coated electrospun nanofibers for endovascular coil embolization

Cited by 2 publications

References 25 publications

Transparent Metallized Microfibers as Recyclable Electrostatic Air Filters with Ionization

Transparent Metallized Microfibers as Recyclable Electrostatic Air Filters with Ionization

Energy-Saving Electrospinning with a Concentric Teflon-Core Rod Spinneret to Create Medicated Nanofibers

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