In vitro human skin barrier perturbation by oleic acid: Thermal analysis and freeze fracture electron microscopy studies

Tanojo, Hanafi; Geest, Anita Bos-van; Bouwstra, Joke A.; Junginger, Hans E.; Boodé, Harry E.

doi:10.1016/s0040-6031(97)00063-4

Cited by 61 publications

(21 citation statements)

References 30 publications

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“…Oleic acid is incorporated into skin lipid, disrupts molecular packaging and alters the level of hydration, thus allowing drug penetration [28]. It has also been described that at high concentrations oleic acid can exist as a separate phase within the lipid bilayers [29,30]. Our results confirm that it can work synergistically with ethanol and glycerol, as proposed by other authors [31].…”

Section: In-vitro Permeation Studysupporting

confidence: 89%

Skin Permeation of Zidovudine from Crosslinked Chitosan Film Containing Terpene Enhancers for Transdermal Use

Singh¹

2013

IOSR-JPBS

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Section: In-vitro Permeation Studysupporting

confidence: 89%

Skin Permeation of Zidovudine from Crosslinked Chitosan Film Containing Terpene Enhancers for Transdermal Use

Singh¹

2013

IOSR-JPBS

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“…SC was isolated by trypsin digestion as described earlier ( 50 ). This procedure does not affect the lipid organization in SC ( 51 ).…”

Section: Biopsy and Small Angle X-ray Diffraction Measurementsmentioning

confidence: 99%

Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients

Janssens

Smeden

Gooris

et al. 2012

Journal of Lipid Research

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397

433

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“…The local severity of uninvolved AE skin was evaluated by local SCORing Atopic Dermatitis (Stalder and Taieb, 1993) and was 0 for all patients. SC was isolated by trypsin digestion (Tanojo et al, 1997) and analyzed by small-angle X-ray diffraction using a microfocus beam (European Synchrotron Radiation Facility, Grenoble, France), similarly as described elsewhere (Bras et al, 2003). The CER composition was examined in SC harvested by tape stripping uninvolved regions from the ventral forearm (PPS tape, Nichiban, Tokyo, Japan) close to the region of the biopsy.…”

Section: To the Editormentioning

confidence: 99%

Lamellar Lipid Organization and Ceramide Composition in the Stratum Corneum of Patients with Atopic Eczema

Janssens

Smeden

Gooris

et al. 2011

Journal of Investigative Dermatology

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109

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Isolation of a Microsporum canis gene family encoding three subtilisin-like proteases expressed in vivo. J Invest Dermatol 119:830-5 Gonzalez A, Sierra R, Cardenas ME et al. (2009) Physiological and molecular characterization of atypical isolates of Malassezia furfur. Quantitative culture of Malassezia species from different body sites of individuals with or without dermatoses. Med Mycol 39:243-51 Naldi L, Rebora A (2009) Clinical practice. Seborrheic dermatitis. N Engl J Med 360:387-96 Oh BH, Lee YW, Choe YB et al. (2010) Epidemiologic study of Malassezia yeasts in seborrheic dermatitis patients by the analysis of 26S rDNA PCR-RFLP. Ann Dermatol 22:149-55 Ran Y, Yoshiike T, Ogawa H (1993) Lipase of Malassezia furfur: some properties and their relationship to cell growth. J Med Vet Mycol 31:77-85 Staib P, Kretschmar M, Nichterlein T et al. (1999) Host-induced, stage-specific virulence gene activation in Candida albicans during infection. Mol Microbiol 32:533-46 Tajima M, Sugita T, Nishikawa A et al. (2008) Molecular analysis of Malassezia microflora in seborrheic dermatitis patients: comparison with other diseases and healthy subjects. J Invest Dermatol 128:345-51 Xu J, Saunders CW, Hu P et al. (2007) Dandruffassociated Malassezia genomes reveal convergent and divergent virulence traits shared with plant and human fungal pathogens. Proc Natl Acad Sci USA

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In vitro human skin barrier perturbation by oleic acid: Thermal analysis and freeze fracture electron microscopy studies

Cited by 61 publications

References 30 publications

Skin Permeation of Zidovudine from Crosslinked Chitosan Film Containing Terpene Enhancers for Transdermal Use

Skin Permeation of Zidovudine from Crosslinked Chitosan Film Containing Terpene Enhancers for Transdermal Use

Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients

Lamellar Lipid Organization and Ceramide Composition in the Stratum Corneum of Patients with Atopic Eczema

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