In-vitro investigation of anti-acne properties of Mangifera indica L. kernel extract and its mechanism of action against Propionibacterium acnes

Poomanee, Worrapan; Chaiyana, Wantida; Mueller, Monika; Viernstein, Helmut; Khunkitti, Watcharee; Leelapornpisid, Pimporn

doi:10.1016/j.anaerobe.2018.05.004

Cited by 45 publications

(59 citation statements)

References 43 publications

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“…These infections generate purulent material forming abscesses and can cause minor infections of the skin and soft tissues and invasive infections such as: infections of the central nervous system, respiratory, gastrointestinal and urinary tract, bacteraemia and osteomyelitis. [16][17][18][19][20] In the present investigation the antibacterial activity of different mango leaf extracts on S. aureus strain ATCC 6538 was evaluated, the ethanolic and hydroalcoholic extracts were used at 50% and 100% dilutions on bacterial cultures, using the diffusion method from Kirby-Bauer wells and it was found that in effect the four dilutions have extremely sensitive activity, there are significant differences between them and in comparison with the positive control (chlorhexidine 0.12%). The results obtained in this research agree with similar studies carried out by other authors.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Antibacterial Activity of the Ethanol Extract vs Hydroalcoholic Extract of the Leaves of Mangifera indica L. (Mango) in Different Concentrations: An In Vitro Study

Cardenas

Mendoza

Chiong

et al. 2020

The Journal of Contemporary Dental Practice

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Aim: To compare the in vitro antibacterial activity of different types of hydroalcoholic extracts of the leaves of the Mangifera indica L. (mango) plant on the strain of Staphylococcus aureus ATCC 6538™. Materials and methods: This study was experimental in vitro and determined the antibacterial activity of four dilutions: Mangifera indica L. ethanol extract (MEE) and Mangifera indica L. hydroalcoholic extract (MHE) at 50% and 100% on cultures of S. aureus ATCC 6538™ comparing with the positive control (chlorhexidine 0.12%) and negative (alcohol 96°) in Mueller Hinton agar cultures using the Kirby-Bauer diffusion method for each study group and incubating the cultures at 37°C for 24 hours.Results: It was found that the 50% and 100% MEE had a smaller size of the inhibitory halo of 21.3 ± 0.5 and 24.1 ± 0.8 mm, respectively. In addition, with respect to the 50% and 100% MHE, it was found that they had a higher antibacterial activity of 24.6 ± 0.5 and 33.5 ± 1.2 mm, respectively. Conclusion: Mango leaf extracts are potent antibacterial, proving 100% MHE to be more effective, thus confirming the presence of active constituents in medicinal plants. Clinical significance: This research has a great clinical applicability due to the opening of research lines that prove the usefulness of these extracts in the therapeutic control of certain oral diseases.

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Section: Discussionmentioning

confidence: 99%

Comparison of the Antibacterial Activity of the Ethanol Extract vs Hydroalcoholic Extract of the Leaves of Mangifera indica L. (Mango) in Different Concentrations: An In Vitro Study

Cardenas

Mendoza

Chiong

et al. 2020

The Journal of Contemporary Dental Practice

View full text Add to dashboard Cite

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“…The anti-microbial agent erythromycin (15 μg/disc) was included as a standard control. Zone of inhibition in mm was measured to compare the anti-microbial activity of plant extracts [6][7][8][9][10][11][12][13].…”

Section: Animalmentioning

confidence: 99%

“…A positive control, containing media with 0.1ml inoculum was maintained to indicate the growth promotion capacity of the media. Test samples of Propionibacterium acnes were incubated under anaerobic condition in an anaerobic jar (Hi-Media) with gas pack for 48h [8,[9][10][11][12][13][14][15].…”

Section: Determination Of Minimum Inhibitory Concentrationmentioning

confidence: 99%

Polyherbal anti acne gel containing extracts of Mangifera indica and Syzygium cumini seeds: bioassay guided activity against Propionibacterium acne

2019

Biointerface Res Appl Chem

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Mangifera indica and Sygygium cumini seeds are rich sources of secondary metabolites and a sustainable cost effective biomaterial. An effective herbal therapy for topical affliction, Acne using such material will prove to be a good alternative to costly and clinically significant antibiotics. The aim of the study was to develop topical polyherbal gel from Mangifera indica and Syzygium cumini for the treatment of acne vulgaris. Plant materials were extracted in methanol and fractionated in different polarity solvents. These fraction were evaluated for antibacterial activity against Propionibacterium acne (P. acne) in-vitro. The most effective fraction was formulated as gel. The formulated gel was evaluated for physico chemical parameters, irritancy, antiacne activity and stability. Methanolic extract was the most active in-vitro against Propionibacterium acne (MTCC 1951). The fabricated gel showed non-stickiness and no irritancy. It showed comparable efficacy as that of clindamycin gel as shown by histopathological study. It also showed the comparable antiacne activity as that of clindamycin gel shown in acne induced wistar albino rats. The formulated gel was stable over a period of 6 months at accelerated stability conditions. It was concluded from the study that methanolic extract of Mangifera indica and Syzygium cumini seeds can be formulated in an aqueous based gel system for topical therapy of mild Acne vulgaris to obtained similar efficacy as that of antibacterial gel (clindamycin) taken as reference standard without its side effects.

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“…Soap Pod helps in getting rid of skin infections and diseases due to its antibacterial properties [8]. Soap pod extracts has been demonstrated to have in vitro antioxidant and anti-tyrosinase activities [9]. Kaffir lime possesses antioxidant, antimicrobial, antibacterial properties and the major compounds are sabinene, β-pinene, limonene, α-pinene, camphene, myrcene, terpinen-4-ol, α-terpineol, linalool, terpinolene and citronellal [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

“…The external mass transfer resistance is negligible [20,21]. Equation (9) can be reduced to the following form:…”

Section: Fick's Law Modelmentioning

confidence: 99%

Chemical Profiling Analysis and Identification the Bioactivities of Herbal Compress Extracts

et al. 2018

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Abstract. The traditional Thai herbal compress is composed of six different types of herbs including Ginger (Zingiber cassumunar), Turmeric (Curcuma longa Linn.), Soap Pod (Acacia concinna), Kaffir lime (Citrus hystrix), Lemongrass (Cymbopogon citratus), and Tamarind (Tamarindus indica Linn.). Herbal compress is used in treatment of Thai traditional massage to relieve the body pain and muscle strains. The objective of this work is to perform chemical profiling and extraction modelling of herbal compress obtained from solvent extraction method. The kinetic models, The second order and Fick's second law, representing the extraction behaviors of bioactive compounds were constructed to fit with experimental data of solvent extraction. Under tested condition, the extraction equilibrium was reached after 360 min and the second-order model gives the best fit for the experimental data with high coefficients of correlation (R 2 = 0.9927). Additionally, chemical profiling analysis showed that the amounts and variations of bioactive components in drying-pretreated herbal compress were more abundant than that of untreated sample. This finding could be applied further for preparation and production of traditional Thai herbal compress in the industrial scale.

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In-vitro investigation of anti-acne properties of Mangifera indica L. kernel extract and its mechanism of action against Propionibacterium acnes

Cited by 45 publications

References 43 publications

Comparison of the Antibacterial Activity of the Ethanol Extract vs Hydroalcoholic Extract of the Leaves of Mangifera indica L. (Mango) in Different Concentrations: An In Vitro Study

Comparison of the Antibacterial Activity of the Ethanol Extract vs Hydroalcoholic Extract of the Leaves of Mangifera indica L. (Mango) in Different Concentrations: An In Vitro Study

Polyherbal anti acne gel containing extracts of Mangifera indica and Syzygium cumini seeds: bioassay guided activity against Propionibacterium acne

Chemical Profiling Analysis and Identification the Bioactivities of Herbal Compress Extracts

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