2024
DOI: 10.3390/biomedicines12122714
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In Vitro Models of Cardiovascular Disease: Embryoid Bodies, Organoids and Everything in Between

Theodora M. Stougiannou,
Konstantinos C. Christodoulou,
Dimos Karangelis

Abstract: Cardiovascular disease comprises a group of disorders affecting or originating within tissues and organs of the cardiovascular system; most, if not all, will eventually result in cardiomyocyte dysfunction or death, negatively impacting cardiac function. Effective models of cardiac disease are thus important for understanding crucial aspects of disease progression, while recent advancements in stem cell biology have allowed for the use of stem cell populations to derive such models. These include three-dimensio… Show more

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