2017
DOI: 10.1016/j.tiv.2017.04.002
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In vitro safety and efficacy evaluations of a complex botanical mixture of Eugenia dysenterica DC. (Myrtaceae): Prospects for developing a new dermocosmetic product

Abstract: In the context of developing a new natural product-based cosmetic, the in vitro efficacy and safety evaluations of a complex botanical mixture based on Eugenia dysenterica leaf hydroalcoholic extract (EDE) (2.5-1000μg/mL) were carried out. Chromatographic analysis demonstrated the presence of the tannin (ellagic acid) and flavonoids (quercetin and gallic acid) which characterize the EDE as a polyphenol-rich mixture. Using HFF-1 fibroblasts, it was shown that EDE promoted cell regeneration after UVA exposure. I… Show more

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Cited by 33 publications
(34 citation statements)
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“…In line with this context, there are numerous studies on the safety of cosmetics. In other words, studies allied with the risks and regulations of trace harmful chemicals [16,20,21,23] and the association between organic/natural ingredients and the safety of cosmetics [24] (some of them argue that organic and natural cosmetics lead to positive effect on consumers' purchase intentions [12,13,25] but on the other hand, contrary to general belief, there are many reports that natural cosmetic ingredients are not free from toxicity [26,27]) are visible. However, researches based on consumers' perception of quality and their trust in accessible information of safety data to them actually and their purchase intentions related to the safety of cosmetics of consumers are rare.…”
Section: Introductionmentioning
confidence: 99%
“…In line with this context, there are numerous studies on the safety of cosmetics. In other words, studies allied with the risks and regulations of trace harmful chemicals [16,20,21,23] and the association between organic/natural ingredients and the safety of cosmetics [24] (some of them argue that organic and natural cosmetics lead to positive effect on consumers' purchase intentions [12,13,25] but on the other hand, contrary to general belief, there are many reports that natural cosmetic ingredients are not free from toxicity [26,27]) are visible. However, researches based on consumers' perception of quality and their trust in accessible information of safety data to them actually and their purchase intentions related to the safety of cosmetics of consumers are rare.…”
Section: Introductionmentioning
confidence: 99%
“…The effective quantum yield of PSII (ΦPSII) and the electron transport rate (ETR) were higher in plants grown with between 50 to 200 mg dm −3 N and 200 mg dm⁻ 3 P ( Figure 2). The ΦNPQ showed a dramatic increase in E. dysenterica plants exposed to 400 mg dm⁻ 3 N and was reduced in plants exposed to 600 mg dm⁻ 3 P (Figure 2). Gas exchange traits in E. dysenterica seedlings grown at varying rates of nitrogen and phosphorus.…”
Section: Physiological Traitsmentioning
confidence: 99%
“…The ratio between shoot dry matter (SDM) and root dry matter (RDM) (SDM/RDM) increased only at the highest N rate ( Figure 3). P at 200 mg dm⁻ 3 produced higher values of H (Figure 3), whereas the highest values of SD, TDM and SDM/RDM in E. dysenterica seedlings were observed at P rates between 200 and 600 mg dm⁻ 3 (Figure 3). (Table S2).…”
Section: Morphological Traitsmentioning
confidence: 99%
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“…The microbiological and sensorial characteristics have encouraged the commercialization of cagaita jelly (ARRUDA et al, 2016) and cagaita wine (OLIVEIRA et al, 2011). As one of the Brazilian Cerrado native plants, the cagaita tree has bioactive compounds with great potential to be exploited (BOLZANI et al, 2012;NOVAES et al, 2013;CORREIA et al, 2016), namely due to its antioxidant effects (ROCHA et al, 2013;MOREIRA et al, 2017). A peptide extracted from the pulp (NCBI accession P86708.1) can be used as a new compound in laxatives (LIMA et al, 2010).…”
Section: Introductionmentioning
confidence: 99%