In vitro studies on phytochemical evaluation and antimicrobial activity of Borassus flabellifer Linn against some human pathogens

Abstract

B. flabellifer exhibited higher rate of growth inhibition against some human pathogens, so it can be used for treatment of some infectious diseases. Further studies are being carried out to separate and purify the individual compounds that are present in seed coat of B. flabellifer by using various chromatographic techniques.

Biogenic synthesis of magnetic iron oxide nanoparticles using inedible borassus flabellifer seed coat: characterization, antimicrobial, antioxidant activity and in vitro cytotoxicity analysis

“…B.subtilis showed the maximum zone of inhibition of 18 mm, 24 mm and 26 mm at all the concentrations of 50 μg ml −1 , 100 μg ml −1 , 500 μg ml −1 respectively. This is in agreement to the previous literature where the extract alone showed highest activity against B.subtilis [28]. The larger zone of inhibition can be accredited to the synergistic activity of the iron oxide nanoparticles and the phytocomponents 50 14 11 17 18 9 9 100 20 18 19 24 11 10 500 23 20 22 26 15 13 coated on the nanoparticles [48].…”

“…Similar results for the presence of elemental composition from the extract have already been reported [47]. The phytochemical constituents in the seed coat extract have been screened for the presence of tannins, flavanoids, saponins, terpenoids, glycosides [28], whereas further investigation needs to be done in order to determine the elemental composition of the seed coat extract.…”

“…The radical scavenging activities of the nanoparticles can be imputed to the presence of bioactive components in the extract that possess good antioxidant activity and hence the surface functionalized iron oxide nanoparticles exhibit appreciable scavenging activity against free radicals [29]. The phytochemicals like flavanoid, tannins, saponnins, glycosides are known to be present in the extract and the free radical scavenging activity thus can be ascribed to the polyphenolic content present in the extract [28]. The green synthesized iron oxide nanoparticles hence can be a potential candidate in various biomedical applications due to their high cytocompatibilty and antioxidant activity.…”

Hydrogel Containing Borassus flabellifer L. Male Flower Extract for Antioxidant, Antimicrobial, and Anti-Inflammatory Activity

“…Wongmanit et al reported the antibacterial activity of B. flabellifer male flower ethanolic extract against Enterococcus faecalis and Staphylococcus aureus , but did not report the activity against Escherichia coli [ 22 ]. Alamelumangai et al reported that the methanolic and ethanolic seed coat of B. flabellifer extract at 50 mg/mL could inhibit the growth of Aspergillus brasiliensis and Bacillus subtilis [ 26 ]. Reshma et al isolated 2,3,4-trihydroxy-5-methylacetophenone from palm juice extract, which showed a broad-spectrum antibacterial activity against Escherichia coli, Mycobacterium smegmatis, Staphylococcus aureus, and Staphylococcus simulans [ 27 ].…”

GC-MS Analysis and Assessment of Antioxidant and Anthelmintic Potential of the Ethanolic Root Extract of Borassus flabellifer Linn.

“…18 Methanolic, ethanolic and aqueous seed extracts have antimicrobial activity. 19 Alcoholic root extract has hypoglycaemic activity 20 and methanolic leaves extract has anthelmintic activity. 21 Ethanolic flower extract has also been reported for anti-inflammatory activity, 22 ethanolic and aqueous seed extracts have diuretic activity, 23 whilst aqueous fruit extract has wound healing activity.…”