In vitro study of the effects of fluoride-releasing dental materials on remineralization in an enamel erosion model

Zhou, San Ling; Zhou, Jun; Watanabe, Shigeru; Watanabe, Koji; Wen, Ling Ying; Xuan, Kun

doi:10.1016/j.jdent.2011.12.016

Cited by 80 publications

(92 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, a significant decrease was detected after an initial period of fluoride release. 13,22 An in vitro study with Clinpro XT (23) showed that resin-based desensitizers did not release sufficient levels of fluoride ions to produce a clinically remarkable impact. Further studies are necessary to evaluate whether fluoride release by these materials has a beneficial effect on relieving DH.…”

Section: Discussionmentioning

confidence: 99%

“…9 The recently available Clinpro TM XT (3M ESPE, Minnesota, USA) is a new paste-liquid that may be used as a site-specific, light-cured desensitizing agent. 10,11,12,13 Ion exchange with dental substrate inherent to GICs enhanced the development of these materials to obtain high fluoride release. 14 Since GICs may also release therapeutic doses of fluoride over time, the activity is an important feature to obstruct tubules in DH treatment.…”

Section: Introductionmentioning

confidence: 99%

“…14 Since GICs may also release therapeutic doses of fluoride over time, the activity is an important feature to obstruct tubules in DH treatment. 11,13,15,16 However, there is no consensus in the literature regarding to the clinical relevance of released fluorides by these materials. 17 The rapid reduction of DH and the long-term duration of these desensitizing effects are critical.…”

Section: Introductionmentioning

confidence: 99%

“…Previous studies reported that the effects of several desensitizing agents were not permanent because they did not properly adhere to the dentin surface. 6,8,13 However, a limited amount of data on the efficacy of desensitizers is available in the literature, especially for long-term assessments of at least 6-months follow-up. 2,4,18,19 Therefore, current randomized, split-mouth clinical trial evaluates and compares the desensitizing efficacy of Clinpro XT and conventional GIC (Vidrion R) in a 6-month follow-up.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Evaluation of dentin hypersensitivity treatment with glass ionomer cements: A randomized clinical trial

et al. 2017

View full text Add to dashboard Cite

A randomized, double-blind, split-mouth clinical trial was performed compared the desensitizing efficacy of the resin-modified glass ionomer cement (GIC) ClinproTM XT (3M ESPE, Minnesota, USA) and the conventional GIC Vidrion R (SS White, Gloucester, UK) in a 6-month follow-up. Subjects were required to have at least two teeth with dentin hypersensitivity. Teeth were divided at random into 2 groups, one group received Clinpro XT and the other conventional GIC Vidrion R. Treatments were assessed by tactile and air blast tests using Visual Analogue Scale (VAS) at baseline, after 20 minutes, and at 7, 15, 21, 30, 90 and 180 days post-treatment. Twenty subjects (152 teeth) were included. Both tests (tactile and air blast) showed a significant reduction of dentin hypersensitivity immediately after the application of Vidrion R and Clinpro XT (20 min). VAS scores obtained along the 6-month follow-up were statistically lower when compared to initial rates (p < 0.05). Both GIC were able to reduce dentin hypersensitivity up to 6-month post-treatment period without statistically significant differences among them (p > 0.05). Both cements provided satisfactory results in long-term dental sensitivity reduction.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of dentin hypersensitivity treatment with glass ionomer cements: A randomized clinical trial

et al. 2017

View full text Add to dashboard Cite

show abstract

“…As technology advances, white spot lesions must be treated with non-invasive techniques to prevent further disease progression and preserve the integrity of tooth structure [1][2][3]. Remineralization of tooth enamel is defined as the process whereby calcium and phosphate ions are supplied from an external source to promote ion-deposition-demineralized enamel crystals to produce mineral gain [4]. Speaking about mineralization, it is fundamental to use the term biomineralization when referring to its formation.…”

Section: Introductionmentioning

confidence: 99%

The Effects of Remineralization via Fluoride Versus Low-Level Laser IR810 and Fluoride Agents on the Mineralization and Microhardness of Bovine Dental Enamel

et al. 2018

View full text Add to dashboard Cite

Abstract:The objective of this study was to assess the mineralization and microhardness of bovine dental enamel surfaces treated with fluoride, tri-calcium phosphate, and infrared (IR) 810 laser irradiation. The study used 210 bovine incisors, which were divided into six groups (n = 35 in each): Group A: Untreated (control), Group B: Fluoride (Durapath-Colgate), Group C: Fluoride+Tri-calcium phosphate (Clin-Pro White-3 M), Group D: Laser IR 810 (Quantum), Group E: Fluoride+laser, and Group F: Fluoride+tri-calcium phosphate+laser). Mineralization was measured via UV-Vis spectroscopy for phosphorus and via atomic absorption spectroscopy for calcium upon demineralization and remineralization with proven agents. Microhardness (SMH) was measured after enamel remineralization. Mineral loss data showed differences between the groups before and after the mineralizing agents were placed (p < 0.05). Fluoride presented the highest remineralization tendency for both calcium and phosphate, with a Vickers microhardness of 329.8 HV0.1/11 (p < 0.05). It was observed that, if remineralization solution contained fewer minerals, the microhardness surface values were higher (r = −0.268 and −0.208; p < 0.05). This study shows that fluoride has a remineralizing effect compared with calcium triphosphate and laser IR810. This in vitro study imitated the application of different remineralizing agents and showed which one was the most efficient for treating non-cavitated injuries. This can prevent the progression of lesions in patients with white spot lesions.

show abstract

Amyloid‐Mediated Remineralization in Pit and Fissure for Caries Preventive Therapy

Yang

Guo

et al. 2022

Adv Healthcare Materials

Self Cite

View full text Add to dashboard Cite

The pits and fissures of teeth have high caries susceptibility, and sealing these areas is considered as an effective method to prevent caries. However, long-term caries prophylaxis cannot be maintained because of the negative effects derived from the technical sensitivity and disadvantages of sealing materials. Herein, a new strategy is proposed to occlude fossae by amyloid-mediated biomimetic remineralization. In contrast to conventional inward blocking from the outside of fossae, amyloid-mediated biomimetic mineralization delivers an amyloid-like protein nanofilm into the deepest zone of the fossae and induces the formation of remineralized enamel inside. Such assembly from lysozyme conjugated with poly (ethylene glycol) enriches the interface with strongly bonded ionsand directs in situ nucleation to achieve enamel epitaxial growth. Not only is the structure of the enamel-like crystalline hydroxyapatite layer but also its mechanical stability is similar to that of natural enamel. Furthermore, the layer shows good biocompatibility and antibacterial properties. On the basis of the findings, it is demonstrated that amyloid-like protein aggregation may provide an enamel remineralization strategy to modify the current clinically available methods of pit and fissure sealing and shows great promise in preventing caries.

show abstract

In vitro study of the effects of fluoride-releasing dental materials on remineralization in an enamel erosion model

Cited by 80 publications

References 45 publications

Evaluation of dentin hypersensitivity treatment with glass ionomer cements: A randomized clinical trial

Evaluation of dentin hypersensitivity treatment with glass ionomer cements: A randomized clinical trial

The Effects of Remineralization via Fluoride Versus Low-Level Laser IR810 and Fluoride Agents on the Mineralization and Microhardness of Bovine Dental Enamel

Amyloid‐Mediated Remineralization in Pit and Fissure for Caries Preventive Therapy

Contact Info

Product

Resources

About