In vitro study on the antimicrobial activity of eleven essential oils against oral cavity microbiota

Somantri, R U; Sugiarto, _; Iriani, E S; Sunarti, T C

doi:10.1088/1755-1315/1063/1/012025

Cited by 3 publications

(1 citation statement)

References 29 publications

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“…Diterpenes having four isoprene units are shown by the formula of C 20 H 32 ( Somantri et al., 2022 ). They are widely found in nature and are defined as compounds having various pharmacological activities ( Kemboi et al., 2021 ).…”

Section: Secondary Metabolitesmentioning

confidence: 99%

Production of secondary metabolites using tissue culture-based biotechnological applications

et al. 2023

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Plants are the sources of many bioactive secondary metabolites which are present in plant organs including leaves, stems, roots, and flowers. Although they provide advantages to the plants in many cases, they are not necessary for metabolisms related to growth, development, and reproduction. They are specific to plant species and are precursor substances, which can be modified for generations of various compounds in different plant species. Secondary metabolites are used in many industries, including dye, food processing and cosmetic industries, and in agricultural control as well as being used as pharmaceutical raw materials by humans. For this reason, the demand is high; therefore, they are needed to be obtained in large volumes and the large productions can be achieved using biotechnological methods in addition to production, being done with classical methods. For this, plant biotechnology can be put in action through using different methods. The most important of these methods include tissue culture and gene transfer. The genetically modified plants are agriculturally more productive and are commercially more effective and are valuable tools for industrial and medical purposes as well as being the sources of many secondary metabolites of therapeutic importance. With plant tissue culture applications, which are also the first step in obtaining transgenic plants with having desirable characteristics, it is possible to produce specific secondary metabolites in large-scale through using whole plants or using specific tissues of these plants in laboratory conditions. Currently, many studies are going on this subject, and some of them receiving attention are found to be taken place in plant biotechnology and having promising applications. In this work, particularly benefits of secondary metabolites, and their productions through tissue culture-based biotechnological applications are discussed using literature with presence of current studies.

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Section: Secondary Metabolitesmentioning

confidence: 99%

Production of secondary metabolites using tissue culture-based biotechnological applications

et al. 2023

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Biological production and application of secondary metabolites and other medicinal products

Pathak

2025

Medicinal Biotechnology

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Microfluidic and impedance analysis of rosemary essential oil: implications for dental health

Joseph,

Petrović,

Ibrahim

et al. 2024

BioMed Eng OnLine

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Background Oral health is closely linked to systemic conditions, particularly non-communicable diseases (NCDs), which can exacerbate oral issues. Essential oils (EOs) have emerged as potential alternatives for oral health due to their antibacterial, anti-inflammatory, and antioxidant properties. Among these, rosemary essential oil (REO) shows promise due to its various biological activities. This study investigates the potential of REO in dental applications using microfluidic devices and electrochemical impedance spectroscopy (EIS) to analyze the electrical properties of REO in artificial saliva (AS) mixtures. Results The study demonstrated significant variations in impedance across different REO concentrations and their mixtures with AS. Higher impedance was observed in REO mixtures, particularly at lower frequencies, indicating distinct electrical properties compared to pure AS. The impedance of REO was influenced by its concentration, with a 1% REO solution showing higher impedance than a 4% solution, possibly due to micelle formation and changes in dielectric properties. Additionally, microfluidic devices enabled precise control over fluid interactions and real-time monitoring, offering valuable insights into REO's behavior in a simulated oral environment. The impedance data demonstrated significant differences in REO–AS mixtures, highlighting potential interactions critical for oral care applications. Conclusions Rosemary essential oil exhibits unique electrical properties, making it a promising candidate for dental applications, particularly in preventing and treating oral diseases. Microfluidic devices enhance the accuracy and reliability of studying REO's interactions with AS, providing a robust platform for future dental research. The findings suggest that REO could be effectively incorporated into oral care products, offering a natural alternative for combating oral pathogens, reducing inflammation, and protecting against oxidative stress. Future research should focus on clinical trials to validate these findings and explore the synergistic effects of REO with other essential oils.

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In vitro study on the antimicrobial activity of eleven essential oils against oral cavity microbiota

Cited by 3 publications

References 29 publications

Production of secondary metabolites using tissue culture-based biotechnological applications

Production of secondary metabolites using tissue culture-based biotechnological applications

Biological production and application of secondary metabolites and other medicinal products

Microfluidic and impedance analysis of rosemary essential oil: implications for dental health

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