In vitro suppression of porcine epidemic diarrhea virus by Panax notoginseng saponins: assessing antiviral potential

Hu, Yiyi; Li, Yunchuan; Zhu, Haodan; Wang, Dandan; Zhou, Junming; Ni, Yanxiu; Guo, Rongli; Fan, Baochao; Li, Bin

doi:10.1007/s00705-024-06020-8

Arch Virol

2024

DOI: 10.1007/s00705-024-06020-8

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In vitro suppression of porcine epidemic diarrhea virus by Panax notoginseng saponins: assessing antiviral potential

Yiyi Hu,

Yunchuan Li,

Haodan Zhu

et al.

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Advances research in porcine enteric coronavirus therapies and antiviral drugs

Liang,

Xu,

Pan

et al. 2024

Veterinary Quarterly

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The porcine enteric coronaviruses (PECs) currently reported include porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), and swine acute diarrhea syndrome coronavirus (SADS-CoV). In the absence of effective treatment, they can cause similar clinical characteristics including weight loss, sleepiness, vomiting, anorexia and fatal diarrhea in neonatal piglets, resulting in significant economic losses to the global pig industry. Although many studies on drugs for treating and combating PECs have been issued. There are still no specific drug targeting PECs and used in clinical production. Therefore, it is necessary to sort out and summarize the research on the treatment and anti PECs drugs, and further development of low toxicity and high efficiency drugs is needed. Here, we review the latest progress of anti PECs drugs, focus on the mechanism of anti PECs reaction of drug components, and try to clarify new strategies for effective control and elimination of PECs. These comprehensive and profound insights will help to further investigate, prevent and control the transmission of PECs infection.

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Advances research in porcine enteric coronavirus therapies and antiviral drugs

Liang,

Xu,

Pan

et al. 2024

Veterinary Quarterly

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show abstract

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In vitro suppression of porcine epidemic diarrhea virus by Panax notoginseng saponins: assessing antiviral potential

Cited by 1 publication

References 37 publications

Advances research in porcine enteric coronavirus therapies and antiviral drugs

Advances research in porcine enteric coronavirus therapies and antiviral drugs

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